Kimura disease is a rare chronic inflammatory disorder of unknown cause, primarily seen in young Asian males. The disease is characterized by painless subcutaneous swelling, blood and tissue eosinophilia and raised IgE levels. Early diagnosis of Kimura’s disease may spare the patient from unnecessary invasive diagnostic procedure. We describe a case of Kimura disease in a 14-year old male presenting with left submandibular swelling and also provide a brief review of the literature.

Epithelioid angiosarcoma (EA) is a subtype of angiosarcoma which is a rare tumor of endothelial origin. Here, we report a case of 15-year-old boy who presented with soft tissue mass lesion in the parotid region mimicking as a benign parotid tumor. Cytology was suggestive of inflammatory swelling. Patient underwent superficial parotidectomy along with the wide excision of the swelling. On histopathology, it was diagnosed as EA. To the best of our knowledge this is the first case report of epithelioid angiosarcoma of the masseter.

Myopericytoma is a benign tumor that shows a pericytic line of differentiation. The lesion is generally located in the dermis and subcutaneous tissue and has a predilection for distal extremities, but may be found in any part of the body. We present a case of 48-year old male who came with painful swelling in right middle finger for the past 2 years. Histopathology showed proliferation of spindle-shaped cells exhibiting a hemangio-pericytomatous pattern with various sized vessels lined by flattened endothelium and surrounded by a concentric arrangement of spindle-shaped cells. Tumor cells showed membranous positivity for smooth muscle actin but negative for desmin and CD34. Hence diagnosis of intravenous myopericytoma was established.

A 53-year-old male patient presented with a diffuse neck swelling since one month, associated with dyspepsia and dyspnoea. On examination the swelling was fixed, had diffuse margins, was hard in consistency and measured 8x6 cm . A right upper cervical lymph node enlargement was also noted which was mobile, firm in consistency, non tender and measured 2x2 cm. Thyroid function tests revealed high serum free T4 (2.06 ng/dl) and low serum TSH (0.016 mU/ml). Serum calcitonin was <2.0 pg/ ml. Ultrasound neck showed diffuse enlargement of predominantly right lobe of thyroid which was replaced by hyperechoic mass lesion AbSTRACTAnaplastic Thyroid Carcinoma (ATC) is a relatively uncommon highly malignant tumour originating from the follicular cells of thyroid gland having poor prognosis. It accounts for 2% to 5% of all thyroid carcinomas and patients typically present with a rapidly growing anterior neck mass with aggressive symptoms. A 53-year-old male presented with diffuse neck swelling measuring 8x6 cm and right cervical lymph node measuring 2x2 cm since one month which was associated with dyspepsia and dyspnoea. Ultrasound and Contrast Enhanced Computed Tomography (CECT) neck revealed enlarged right lobe of thyroid and multiple enlarged cervical lymph nodes with soft tissue density nodules in bilateral lungs. Fine Needle Aspiration (FNA) from the swelling revealed giant cell, spindle cell and squamoid pattern. Focal areas showed follicular epithelial cells arranged in repeated microfollicular pattern suggesting an underlying follicular neoplasm. FNAC smears from the lymph node also revealed similar findings. Based on the cytomorphological and radiological findings, final diagnosis of ATC probably arising from underlying follicular carcinoma with cervical lymph node and lung metastasis was given. FNAC leads to prompt and definitive diagnosis, so that therapy can be initiated as soon as possible for better outcome. Multimodality therapy (surgery, external beam radiation, and chemotherapy) is the mainstay of treatment.

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