Kidney Transplantation: Single Center Experience

Sozener, Ulas; Eker, Tevfik; Ersöz, Sadık

doi:10.14744/semb.2018.09794

Cited by 3 publications

(5 citation statements)

References 19 publications

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“…This is similar to figures reported in Indonesia, where ESRD was caused by DM in 26% of the patients [15]. However, studies conducted in other countries reported a significantly lower percentage compared to the present study [16,17,19]. These differences are probably related to early screening, patients' compliance to medications, and lifestyle modification.…”

Section: Discussionsupporting

confidence: 86%

“…In the present study, the main cause of ESRD was hypertension, which was found in 117 (35%) patients. Similar figures were reported in studies conducted in Indonesia and Turkey where hypertension was reported in 37.4% and 47% of the patients, respectively [15,16]. In comparison, studies conducted in Australia and the United States of America (USA) found that hypertension was the cause of ESRD in only 4.4% and 5.4% of the patients, respectively [17,18].…”

Section: Discussionsupporting

confidence: 82%

“…Likewise, a local study conducted in Jeddah, one of the largest cities in the country, reported similar values with 77.3% of kidney transplants being from living donor transplants and 22.7% from deceased donor transplants [20]. In other studies conducted in Turkey and Indonesia, nearly all recipients received kidneys from living donors [16,17], while other studies did not report the involvement of cadaveric transplants in their kidney transplant programs [17][18][19]. This could be attributed to the superiority of living donor transplants over deceased donor transplants and living donor transplants being more available in some countries compared to others.…”

Section: Discussionmentioning

confidence: 64%

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Incidence Rate and Predictors of Delayed Graft Function Among Adult Kidney Transplant Recipients at a Tertiary Care Hospital in Riyadh, Saudi Arabia

Almisfer¹,

Qasim²,

Alqahtani³

et al. 2021

Cureus

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BackgroundDelayed graft function (DGF) is the most common early postoperative complication of renal transplantation. The occurrence of DGF can lead to both early and late devastating consequences on the allograft's survival. The risk of developing this complication can increase with certain factors that are related to both the donor and the recipient. In the present study, we aimed to detect the incidence rate of DGF among patients attending a tertiary care hospital in Riyadh, Saudi Arabia, and to investigate potential predictors of DGF. Materials and methodsThis retrospective chart review was conducted at King Abdulaziz Medical City (KAMC), a tertiary care hospital in Riyadh, Saudi Arabia. The inclusion criteria were all patients, 18 years or older, who had renal transplantation from January 1, 2016, to March 31, 2020. Patients who had a second renal transplant, or renal transplantation in a different hospital and were followed up at KAMC were excluded. Patients' medical records were accessed using the BESTCare electronic system to obtain the patients' demographic data. A Chisquare test was used to test for the association between a predictor and a delay in graft function. ResultsA total of 344 patients were enrolled in the present study, approximately half of whom were males (56.6%, n=189). Around one-half (49.4%) were aged between 40 and 64 years. The most common cause of renal failure was hypertension, which was found in 117 (35%) patients, followed by diabetes mellitus (DM) in 94 (28.1%) patients. Most organ donors 258 (77.2%) were alive. A total of 23 (6.9%) participants developed DGF. Mycophenolate mofetil (MMF) was found to be significantly associated with DGF (P < 0.001). Those who took MMF (5.9%) had a significantly lower rate of DGF compared to those who did not (36.4%). A significantly higher rate of DGF was seen in patients whose transplants were taken from deceased donors (15.5%) compared to living donor transplants (3.9%). Gender, age, body mass index (BMI), recipient blood type, donor blood type, and cause of renal failure were not associated with DGF. ConclusionsOnly 6.9% of the study's participants exhibited DGF. The observed rate was lower than the ones detected in the literature. Those who took MMF had a significantly lower rate of DGF compared to those who did not. Transplants of deceased donors (15.5%) showed a significantly higher rate of DGF. Larger multicenter studies are required to further investigate DGF in a region with a high prevalence of organ failure and a higher need for transplantations, such as Saudi Arabia.

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Section: Discussionsupporting

confidence: 86%

Section: Discussionsupporting

confidence: 82%

Section: Discussionmentioning

confidence: 64%

See 1 more Smart Citation

Incidence Rate and Predictors of Delayed Graft Function Among Adult Kidney Transplant Recipients at a Tertiary Care Hospital in Riyadh, Saudi Arabia

Almisfer¹,

Qasim²,

Alqahtani³

et al. 2021

Cureus

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“…It has been demonstrated to provide improvements in both graft and patient survival in comparison to transplantation from a deceased donor[ 1 ]. Pre-emptive transplantation, which occurs prior to the recipient’s requirement for dialysis, has demonstrated improvements in patient and graft survival in comparison to implantation after the commencement of dialysis[ 2 , 3 ]. The cumulative benefit of pre-emptive live donor transplantation should provide tangible benefits.…”

Section: Introductionmentioning

confidence: 99%

Pre-emptive live donor kidney transplantation-moving barriers to opportunities: An ethical, legal and psychological aspects of organ transplantation view

Dellen¹,

Burnapp²,

Citterio³

et al. 2021

WJT

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Live donor kidney transplantation (LDKT) is the optimal treatment modality for end stage renal disease (ESRD), enhancing patient and graft survival. Pre-emptive LDKT, prior to requirement for renal replacement therapy (RRT), provides further advantages, due to uraemia and dialysis avoidance. There are a number of potential barriers and opportunities to promoting pre-emptive LDKT. Significant infrastructure is needed to deliver robust programmes, which varies based on socio-economic standards. National frameworks can impact on national prioritisation of pre-emptive LDKT and supporting education programmes. Focus on other programme’s components, including deceased kidney transplantation and RRT, can also hamper uptake. LDKT programmes are designed to provide maximal benefit to the recipient, which is specifically true for pre-emptive transplantation. Health care providers need to be educated to maximize early LDKT referral. Equitable access for varying population groups, without socio-economic bias, also requires prioritisation. Cultural barriers, including religious influence, also need consideration in developing successful outcomes. In addition, the benefit of pre-emptive LDKT needs to be emphasised, and opportunities provided to potential donors, to ensure timely and safe work-up processes. Recipient education and preparation for pre-emptive LDKT needs to ensure increased uptake. Awareness of the benefits of pre-emptive transplantation require prioritisation for this population group. We recommend an approach where patients approaching ESRD are referred early to pre-transplant clinics facilitating early discussion regarding pre-emptive LDKT and potential donors for LDKT are prioritized for work-up to ensure success. Education regarding pre-emptive LDKT should be the norm for patients approaching ESRD, appropriate for the patient’s cultural needs and physical status. Pre-emptive transplantation maximize benefit to potential recipients, with the potential to occur within successful service delivery. To fully embrace preemptive transplantation as the norm, investment in infrastructure, increased awareness, and donor and recipient support is required.

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“…[ 2 ] Kidney transplantation is the most important treatment for end-stage renal failure. [ 3 ] Although renal transplant patients are a high-risk patient group due to the immunosuppressive drugs they have taken and comorbid diseases, heart valve surgeries can be performed with acceptable mortality and morbidity. [ 4 ] We present a case who underwent tricuspid ring annuloplasty (TRA) before being followed up with renal transplantation and then successfully performed redo tricuspid valve replacement (TVR) and pulmonary valve replacement (PVR).…”

mentioning

confidence: 99%

Redo Tricuspid and Pulmonary Valve Replacement with On-X in Renal Transplant Patient: A Case Report

Beyazal

2024

Sisli Etfal

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Surgical treatment is recommended in patients with symptomatic severe tricuspid regurgitation and pulmonary regurgitation. Although renal transplant patients are a high-risk patient group for cardiac surgery, heart valve surgeries can be performed successfully. There are a limited number of studies published on this subject in the literature. Therefore, we present a case who underwent tricuspid ring annuloplasty (TRA) before being followed up with renal transplantation and then successfully performed redo tricuspid valve replacement (TVR) and pulmonary valve replacement (PVR).

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Kidney Transplantation: Single Center Experience

Cited by 3 publications

References 19 publications

Incidence Rate and Predictors of Delayed Graft Function Among Adult Kidney Transplant Recipients at a Tertiary Care Hospital in Riyadh, Saudi Arabia

Incidence Rate and Predictors of Delayed Graft Function Among Adult Kidney Transplant Recipients at a Tertiary Care Hospital in Riyadh, Saudi Arabia

Pre-emptive live donor kidney transplantation-moving barriers to opportunities: An ethical, legal and psychological aspects of organ transplantation view

Redo Tricuspid and Pulmonary Valve Replacement with On-X in Renal Transplant Patient: A Case Report

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