Keratosis lichenoides chronica mimicking verrucous secondary syphilis

Jayaraman, Anu G; Pomerantz, David K.; Robinson‐Bostom, Leslie

doi:10.1067/s0190-9622(03)00894-6

Cited by 16 publications

(12 citation statements)

References 7 publications

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“…Nail dystrophy occurs in 30% of patients, including yellow discolouration, thickening, ridging of the nail plate and hyperkeratosis in nail bed. 7 Our patient also had nail dystrophy.…”

Section: Reportmentioning

confidence: 54%

“…Differential diagnosis includes lichen planus, pityriasis lichenoides et varioliformis acuta, mycosis fungoides and connective tissue diseases. [5][6][7] Our patient initially had skin lesions and histological and immunological findings (antineutrophil antibodies, IgG in the dermoepidermal layer) suggesting a connective tissue disease, possibly lupus erythematosus. Multiple skin biopsies from several sites were taken to reach the correct diagnosis.…”

Section: Reportmentioning

confidence: 90%

“…It is resistant to topical therapy and usually does not show improvement after systemic steroids, antimalarials, sulphones, tetracycline, erythromycin, superficial radiotherapy, anthralin, tretinoin, chloroquine sulphate, topical tar preparations, methotrexate, gold or ciclosporin. 6,7 However, photochemotherapy 5,8 and retinoids may benefit some patients with or without the addition of tacalcitol, an active form of vitamin D3. 6,9,10 We obtained a small improvement after in our patient using PUVA therapy.…”

Section: Reportmentioning

confidence: 99%

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Keratosis lichenoides chronica: a diagnostic and therapeutic challenge.

et al. 2006

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“…Nail dystrophy occurs in 30% of patients, including yellow discolouration, thickening, ridging of the nail plate and hyperkeratosis in nail bed. 7 Our patient also had nail dystrophy.…”

Section: Reportmentioning

confidence: 54%

Section: Reportmentioning

confidence: 90%

Section: Reportmentioning

confidence: 99%

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Keratosis lichenoides chronica: a diagnostic and therapeutic challenge.

et al. 2006

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“…Th e following therapeutic modalities proved to be ineffi cient: systemic and topical corticosteroids, systemic antimalarials, diaminodiphenylsulfone, tetracyclines, cyclosporine, methotrexate (90,91). Various results were obtained with systemic administration of acitretin, isotretinoin, etretinate, psoralen ultraviolet A radiation (PUVA), retinoids combined with PUVA or with narrow-band ultraviolet B radiation (NB-UVB) (4), as well as topical calcipotriol (89,98) and NB-UVB monotherapy (106).…”

Section: Patients Reported Under a Controversial Diagnosis Of Keratosmentioning

confidence: 99%

Keratosis Lichenoides Chronica – a Case Report and Literature Review

Paravina

Cvetanović²,

Kostov³

et al. 2014

Serbian Journal of Dermatology and Venereology

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linear and reticular red to purple papules with white scaly surface. Before the appearance of skin lesions, the patient's history was unremarkable and he denied taking any medications. He was treated under the diagnosis of psoriasis vulgaris, and lichen verrucosus. In 2014, he underwent phimosis surgery. Th ere was no family history of skin conditions. ExaminationOn admission, the patient presented with symmetrical generalized eruptions of erythemolivid to dark livid papules and nodules with a keratotic surface, in a solitary, linear or reticular pattern on the lower lateral parts of the trunk and along the extremities ( Figures 1-3); the infi ltrated lesions were prominent, verrucous and hyperkeratotic. Mild erythematosquamous lesions were present on the face. Solitary erythematous papules on erythematous base T he idea for this paper on keratosis lichenoides chronica (KLC) was born after the fi rst visit of a patient with an unusual clinical picture resembling both psoriasis and lichen planus, but also distinct from them, posing a diagnostic and therapeutic dilemma. After a consultation with Prof. Danilo Stevanović, whom we hereby wish to thank, and repeated histopathological examinations, the diagnosis of keratosis lichenoides chronica was confi rmed. Papers of Böer (1) Case report Case historyWe report a 40-year old man who developed skin lesions on the trunk and extremities more than 10 years earlier: asymptomatic, symmetrically distributed AbstractKeratosis lichenoides chronica represents a distinct entity, a rare disease of unknown etiology and pathogenesis, with clinical manifestations which, although typical, require extensive differential diagnosis. The course of the disease is chronic, progressive, and it is resistant to various treatment options, so despite variations in the clinical picture it is really easier to diagnose than to treat. This is a case report of a male patient in whom the diagnosis of keratosis lichenoides chronica was based on typical clinical picture, repeated biopsies and histopathological findings, course of the disease and poor response to any therapy.

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“…The treatment of KLC is a matter of debate. Topical and systemic corticosteroids, anti‐malarials, dapson, tetracycline, cyclosporine and methotrexate have been shown to be ineffective in most reported cases 6,7 . Oral acitretin, isotretinoin, etretinate, psoralen and ultraviolet A (PUVA), retinoid PUVA and topical calcipotriol have been utilized with mixed results 6,8 .…”

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confidence: 99%