Keratosis Lichenoides Chronica – a Case Report and Literature Review

Abstract

linear and reticular red to purple papules with white scaly surface. Before the appearance of skin lesions, the patient's history was unremarkable and he denied taking any medications. He was treated under the diagnosis of psoriasis vulgaris, and lichen verrucosus. In 2014, he underwent phimosis surgery. Th ere was no family history of skin conditions. ExaminationOn admission, the patient presented with symmetrical generalized eruptions of erythemolivid to dark livid papules and nodules with a keratotic surface, in a solitary, linear or reticular pattern on the lower lateral parts of the trunk and along the extremities ( Figures 1-3); the infi ltrated lesions were prominent, verrucous and hyperkeratotic. Mild erythematosquamous lesions were present on the face. Solitary erythematous papules on erythematous base T he idea for this paper on keratosis lichenoides chronica (KLC) was born after the fi rst visit of a patient with an unusual clinical picture resembling both psoriasis and lichen planus, but also distinct from them, posing a diagnostic and therapeutic dilemma. After a consultation with Prof. Danilo Stevanović, whom we hereby wish to thank, and repeated histopathological examinations, the diagnosis of keratosis lichenoides chronica was confi rmed. Papers of Böer (1) Case report Case historyWe report a 40-year old man who developed skin lesions on the trunk and extremities more than 10 years earlier: asymptomatic, symmetrically distributed AbstractKeratosis lichenoides chronica represents a distinct entity, a rare disease of unknown etiology and pathogenesis, with clinical manifestations which, although typical, require extensive differential diagnosis. The course of the disease is chronic, progressive, and it is resistant to various treatment options, so despite variations in the clinical picture it is really easier to diagnose than to treat. This is a case report of a male patient in whom the diagnosis of keratosis lichenoides chronica was based on typical clinical picture, repeated biopsies and histopathological findings, course of the disease and poor response to any therapy.

Nekam's disease

“…KLC, also known as Nekam's disease, is a rare mucocutaneous skin disease of unknown etiology with 128 cases reported in the literature till date[4] and very few from India.…”

“…concluded KLC as a chronic, progressive disease, easy to diagnose despite its variations in presentation but very difficult to treat. [4] Ruiz-Maldonado et al . compared 8 cases of pediatric onset KLC with that of adult onset and opined that the former represent a subset of the latter with special genetic and clinical characteristics such as facial erythematous and purpuric macules, eyebrow, and eyelash alopecia.…”