KARAKTERISASI DAN SKRINING FITOKIMIA DAUN PIRDOT (Saurauia vulcani Korth.)

Gurning, Kasta; Simanjuntak, Helen Anjelina

doi:10.31604/eksakta.v5i2.98-105

Cited by 7 publications

(6 citation statements)

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“…The examination of ash content aims to provide an overview of the internal and external mineral content derived from the initial process of raw materials to become simpler. Determination of total ash content is carried out to determine the level of inorganic compounds in simplicity, such as metals K, Ca, Na, Pb, and Hg [21]. The results of the examination of ash content obtained a value of 6.96%.…”

Section: Examination Of Simplicity Powder Characteristicsmentioning

confidence: 99%

Phytochemical Screening of Phaleria macrocarpa (Scheff.) Boerl.) and Antibacterial Activity Test of Ethanol Extract Against Staphylococcus aureus Bacteria

Rizki

Harahap

Sitorus

2023

International Journal of Science, Technology & Management

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Phaleria macrocarpa is known as one of the medicinal plants in Indonesia. Almost all parts of the plant have chemical content that is useful for being used as medicine. The growing use of crown plants by the community for various diseases requires a series of tests to obtain traditional medicine preparations that are safe for human use. The purpose of this study was to identify the content of secondary metabolite compounds (alkaloids, flavonoids, saponins, tannins, steroids, triterpenoids, and glycosides) and the antibacterial activity of Staphylococcus aureus with the good method because the good method has the advantage that it is easier to measure the area of the inhibition zone formed because an antibacterial activity is not only on the upper surface of nutrient agar but also at the bottom. The results of phytochemical screening showed that the flesh of Phaleria macrocarpa (Scheff). The results of testing the antibacterial activity of an ethanol extract of crown Phaleria macrocarpa (Scheff) fruit flesh (Boerl) were positive for alkaloids, flavonoids, glycosides, saponins, tannins, and steroids. Boerl.) showed effective results at a concentration of 40 mg/ml against Staphylococcus aureus bacteria with an inhibition zone diameter of 14 mm; the antibacterial activity was categorized as strong.

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Section: Examination Of Simplicity Powder Characteristicsmentioning

confidence: 99%

Phytochemical Screening of Phaleria macrocarpa (Scheff.) Boerl.) and Antibacterial Activity Test of Ethanol Extract Against Staphylococcus aureus Bacteria

Rizki

Harahap

Sitorus

2023

International Journal of Science, Technology & Management

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“…Skrining fitokimia bertujuan untuk mengidentifikasi golongan senyawa metabolit sekunder yang terkandung dalam ekstrak atau simplisia sebagai penentu potensi aktivitasnya sebagai obat (12).…”

Section: Skrining Fitokimaunclassified

Potensi Penghambatan Enzim Αlfa-Glukosidase dan Tes Toleransi Glukosa Oral (TTGO) Ektrak Daun Dadap Serep (Erythrina subumbrans (Hassk) Merr.)

Susilawati

Astuti

Suprijono

2023

JFI

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Abstrak: Tanaman dadap serep memiliki kandungan flavonoid yang berpotensi dapat menurunkan kadar glukosa dalam darah dan mengurangi penyerapan glukosa di usus. Tujuan penelitian untuk mengetahui aktivitas penghambatan enzim α-glukosidase dan pengaruh pemberian Ekstrak Etanol Daun Dadap Serep (EEDDS) terhadap kadar glukosa darah tikus putih jantan galur wistar serta dosis efektifnya. Metode penelitian menggunakan metode in vitro dengan penghambatan enzim α-glukosidase dan metode in vivo Tes Toleransi Glukosa (TTGO) dengan induksi amylum manihot menggunakan 25 ekor tikus yang dibagi menjadi 5 kelompok dengan dosis EEDDS 100, 200, dan 400 mg/kgBB, kemudian diukur kadar glukosa darahnya selama 120 menit. Hasil penelitian inhibisi enzim α-glukosidase EEDDS menunjukkan nilai % inhibisi paling baik yaitu 41,81% pada 100 ppm dan nilai % inhibisi terendah pada 10 ppm yaitu 13,33% dengan nilai IC50 sebesar 146,30 ppm dimana termasuk kategori lemah dalam menghambat α-glukosidase. Hasil penelitian TTGO induksi amylum manihot, EEDDS 400 mg/KgBB memiliki efek penurunan kadar glukosa darah secara signifikan pada T60 sampai T120. . Kesimpulan pada penelitian ini adalah ekstrak etanol daun dadap serep mempunyai potensi sebagai antihiperglikemia secara in vitro maupun in vivo.

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“…The ash content examination aims to provide an overview of internal and external mineral content originating from the initial process of raw materials to become dried powder [19]. Determination of total ash content carried out to determine the levels of inorganic compounds in dried powder, for example metals K, Ca, Na, Pb, and Hg [20]. The results of the examination of the ash content obtained a value of 1.69%.…”

Section: 10mentioning

confidence: 99%

“…These results indicate a low ash content where the internal mineral content in Solanum mauritianum Scop leaves is quite low. Acid insoluble ash content indicates the presence of mineral or metal contamination that is not soluble in acid [20]. The yield of acid insoluble ash content in dried powder was 0.69%.…”

Section: 10mentioning

confidence: 99%

Phytochemical Screening and Antibacterial Activity Ethanolic Extract of Solanum mauritianum Scop Leaves Against Staphylococcus aureus and Pseudomonas aeruginosa

Masfria

Sitorus

2022

International Journal of Science, Technology & Management

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According to the Karo people, Solanum mauritianum Scop leaves are widely used as traditional medicine, which is used topically to treat sprains, wounds, and bruises because of their high phenol content. The purpose of this study was to identify the content of secondary metabolites (alkaloids, flavonoids, saponins, tannins, steroids, triterpenoids, and glycosides) that inhibit the antibacterial activity of Staphylococcus aureus and Pseudomonas aeruginosa by the diffusion method using paper discs from the ethanolic extract of Solanum mauritianum Scop leaves. The results of phytochemical screening showed that Solanum mauritianum Scop leaves were positive for alkaloids, flavonoids, glycosides, saponins, tannins, and steroids. Results The antibacterial activity test of the ethanolic extract of Solanum mauritianum Scop leaves showed effective results at a concentration of 80 mg/mL on Staphylococcus aureus with an inhibition zone diameter of 14.54 ± 0.13 mm. Meanwhile, Pseudomonas aeruginosa showed effective results at a concentration of 300 mg/mL with an inhibition zone diameter of 15.70 ± 0.09 mm. Both bacteria showed activity in the strong category. Conclusion The ethanolic extract of Solanum mauritianum Scop leaves has antibacterial activity against both test bacteria with a strong category

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KARAKTERISASI DAN SKRINING FITOKIMIA DAUN PIRDOT (Saurauia vulcani Korth.)

Cited by 7 publications

References 0 publications

Phytochemical Screening of Phaleria macrocarpa (Scheff.) Boerl.) and Antibacterial Activity Test of Ethanol Extract Against Staphylococcus aureus Bacteria

Phytochemical Screening of Phaleria macrocarpa (Scheff.) Boerl.) and Antibacterial Activity Test of Ethanol Extract Against Staphylococcus aureus Bacteria

Potensi Penghambatan Enzim Αlfa-Glukosidase dan Tes Toleransi Glukosa Oral (TTGO) Ektrak Daun Dadap Serep (Erythrina subumbrans (Hassk) Merr.)

Phytochemical Screening and Antibacterial Activity Ethanolic Extract of Solanum mauritianum Scop Leaves Against Staphylococcus aureus and Pseudomonas aeruginosa

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