2016
DOI: 10.1111/aos.13086
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Juxtapapillary choroid is thinner in normal‐tension glaucoma than in healthy eyes

Abstract: Decreased microvascular circulation in the ONH as a result of juxtapapillary choroidal thinning could be an important part of the pathogenesis of optic nerve damage in NTG.

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Cited by 35 publications
(54 citation statements)
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“…These findings concur with the notion that thinning of the choroid might originate in vascular insufficiency of the choroidal vasculature. [24][25][26][27][28] Meanwhile, CVI did not show any significant relationship with RNFL thickness, VF MD, or PSD. These findings may add to the literature that choroidal thickness, which may reflect the choroidal vasculature, is not associated with the presence or severity of glaucoma.…”
Section: Discussionmentioning
confidence: 80%
See 1 more Smart Citation
“…These findings concur with the notion that thinning of the choroid might originate in vascular insufficiency of the choroidal vasculature. [24][25][26][27][28] Meanwhile, CVI did not show any significant relationship with RNFL thickness, VF MD, or PSD. These findings may add to the literature that choroidal thickness, which may reflect the choroidal vasculature, is not associated with the presence or severity of glaucoma.…”
Section: Discussionmentioning
confidence: 80%
“…[28][29][30] On the other hand, given that the study subjects were matched by age and VF MD according to the main purpose of this study (i.e., to evaluate CVI according to MvD_P), the generalizability of the current results to the general population of glaucoma patients might be limited. Given that the pathogenic role of the choroidal structure in the pathogenesis of glaucoma is controversial, 3,[26][27][28][29][30][31][32][33] further studies with large numbers of study subjects are required to better elucidate the relationships among the key factors (i.e., glaucoma severity, choroidal thickness, CVI, and MvD_P).…”
Section: Discussionmentioning
confidence: 99%
“…The JPCT was measured in radial B-scan images obtained using the SS-OCT device (DRI OCT Triton, Topcon), as described previously 11. In brief, the JPCT was measured at the 24 meridians from the 12 radial scan images, using the manual calliper and drawing tool of the IMAGEnet six software (V.1.21).…”
Section: Methodsmentioning
confidence: 99%
“…, ; Lee et al. ). For central serous choroidopathy and polypoidal choroidal vasculopathy, an abnormal thick subfoveal choroid has become a conditio sine qua non for making the diagnosis, to cite only a few examples (Imamura et al.…”
Section: Introductionmentioning
confidence: 99%
“…As the landmark study by Spaide and colleagues showing the use of the enhanced depth imaging mode to visualize the choroid, the assessment of the choroid has become a mainstay for the diagnosis of choroidal and retinal diseases (Spaide et al 2008;Fujiwara et al 2009;Imamura et al 2009;Ikuno et al 2010;Gupta et al 2015aGupta et al , 2016Lee et al 2016). For central serous choroidopathy and polypoidal choroidal vasculopathy, an abnormal thick subfoveal choroid has become a conditio sine qua non for making the diagnosis, to cite only a few examples Chung et al 2011).…”
Section: Introductionmentioning
confidence: 99%