Justification of Traditional Uses of  (Shatavari) - A Miracle Herb

Karim, Samira; Islam, Md. Shariful; Tasnim, Zarin; Laboni, Farhina Rahman; Julie, Azima Sultana; Labu, Zubair Khalid

doi:10.2174/1874847301704010036

Cited by 2 publications

(2 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Positive control streptokinase [23,24] was used for the assessment of thrombolytic activity which was exhibited significant percent of clot lysis (average value, 65.15 ± 0.16%), whereas, the negative control was showed negligible (average value, 8.20 ± 0.16%) percent of clot lysis. The percentages of clot lysis by seven leaves extract were observed in the following order namely, Uncaria cordata (27.36 ± 0.23%), Antidesma cuspidatum (21.64 ± 0.25%), Scaphium macropodum (20.74 ± 0.43%), Uncaria acida (19.90 ± 0.43%), Piper porphyrophyllum (12.88 ± 0.33%) respectively.…”

Section: Thrombolytic Activitymentioning

confidence: 99%

Cytotoxic Activity on Brine Shrimp, MCF-7 Cell Line and Thrombolytic Potential: Seven Different Medicinal Plant Leaves Extract

Azad¹,

Jainul²,

Labu³

2018

J. Sci. Res.

View full text Add to dashboard Cite

The aim of our study was to find out the preliminary cytotoxic and thrombolytic effect of the seven selected medicinal plant leaves extract. In cytotoxic activity, out of the seven leaves extract three of them exhibited stronger brine shrimp lethality with LC 50 122.548 (Uncaria acida), 170.861 (Leea indica) and 175.469 (Piper porphyrophyllum) μg /mL respectively, and on MCF-7 cell line, they also exhibited moderate cytotoxic activity with different concentration of the extract of the same plant leaves such as,Uncaria acida (72.31, 56.22, 38.12 and 9.24%), Leea indica (67.31, 58.22, 43.12 and 15.24%), Piper porphyrophyllum (65.88, 48.12, 40.12 and 21.34%). In thrombolytic assessments, all the leaves extract showed moderate (considering > 20% moderate; **p < 0.01; *p < 0.05) clot lysis activity, but among the extracts, Uncaria cordata (27.36 ± 0.10%) showed the highest and Stachytarpheta indica the lowest (6.14 ± 0.20%) percent clot lysis as compared with the standard streptokinase (65.15 ± 0.16%). This study was conducted to legalize the folkloric use of seven medicinal plant leaves.

show abstract

Section: Thrombolytic Activitymentioning

confidence: 99%

Cytotoxic Activity on Brine Shrimp, MCF-7 Cell Line and Thrombolytic Potential: Seven Different Medicinal Plant Leaves Extract

Azad¹,

Jainul²,

Labu³

2018

J. Sci. Res.

View full text Add to dashboard Cite

show abstract

“…The clear supernatant was decanted, and remaining RBC cells were undertaken for membrane stabilizing activity. Finally, cellular components (0.5 ml erythrocyte suspension, 5 ml hypotonic solution, and 50 mM NaCl in 10 mM sodium phosphate buffered saline) were well mixed for in vitro membrane stabilizing assay [29].…”

Section: Sample Preparation For Membrane Stabilization Assaymentioning

confidence: 99%

Potentiality of Crataeva nurvala bark in the management of thrombosis and membrane stabilization in the rural area, Bangladesh.

Uddin¹,

Laboni²,

Karim³

et al. 2018

Appl Med Res

Self Cite

View full text Add to dashboard Cite

Aim: Crataeva nurvala (C. nurvala) is a medicinally active plant, potentially used as traditional means of treating many health ailments such as prostatitis, prostate enlargement, inflammatory conditions, heart disease, thyroid and endocrine disorder, and urinary tract infection, respectively, in the rural region of Tangail, Jamalpur, Sherpur, and Barishal district since primitive era. In our concurrent research, the bark of this plant was undertaken in order to justify its folkloric history of thrombolytic, membrane stabilizing activity in vitro model, and for the quantification of total phenol content. Methods: The concentrated methanol extract partitioned into different fractions showed different amount of yield like 18.2 g of petroleum ether, 13 g of carbon tetrachloride, 11.1 g of chloroform, and 9.9 g of aqueous, respectively, then all of the fractioned extracts were employed to investigate folkloric uses of thrombolytic and membrane stabilizing potential in vitro models. Results: In the extrapolation of thrombolytic assay, petroleum ether fractioned exhibit the highest percent of clot lysis (27.36% ± 0.10%) activity compared with other fractioned and extract. Crude methanolic extract profoundly inhibited the breakdown of erythrocytes membrane (65.79% ± 0.40%)-induced by hypnotic solution and heat. On the other hand, acetylsalicylic acid (reference standard) resulted in 83.147% ± 0.39% inhibition of clot lysis. Alternatively, aqueous soluble fraction exposed slightly higher level of membrane stabilizing activity provoked by heat-induced hemolysis (75.3 ± 0.39). Conclusions:The present study was investigated to confirm the medicinal value of C. nurvala bark as a thrombolytic and membrane stabilizing agent. ARTICLE HISTORY

show abstract

Justification of Traditional Uses of (Shatavari) - A Miracle Herb

Cited by 2 publications

References 15 publications

Cytotoxic Activity on Brine Shrimp, MCF-7 Cell Line and Thrombolytic Potential: Seven Different Medicinal Plant Leaves Extract

Cytotoxic Activity on Brine Shrimp, MCF-7 Cell Line and Thrombolytic Potential: Seven Different Medicinal Plant Leaves Extract

Potentiality of Crataeva nurvala bark in the management of thrombosis and membrane stabilization in the rural area, Bangladesh.

Contact Info

Product

Resources

About