Justicia pectoralis Jacq: , Acanthaceae: preparation and characterisation of the plant drug including chromatographic analysis by HPLC-PDA

Fonseca, Francisco Noé da; Silva, Aline Holanda; Leal, Luzia Kalyne Almeida Moreira

doi:10.1590/s0102-695x2010005000049

Cited by 22 publications

(16 citation statements)

References 15 publications

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“…Chemical composition. Coumarins (mainly coumarin and umbelliferone); flavonoids (e.g., quercetin, kaempferol, swertisin, and derivatives) (Lino et al, 1997;Oliveira et al, 2000); lignans (e.g., justicidin B) (Joseph et al, 1988).…”

Section: Hedera Helix L -Araliaceae (Leaves)mentioning

confidence: 99%

COVID-19: Is There Evidence for the Use of Herbal Medicines as Adjuvant Symptomatic Therapy?

et al. 2020

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Background: Current recommendations for the self-management of SARS-Cov-2 disease (COVID-19) include self-isolation, rest, hydration, and the use of NSAID in case of high fever only. It is expected that many patients will add other symptomatic/adjuvant treatments, such as herbal medicines. Aims: To provide a benefits/risks assessment of selected herbal medicines traditionally indicated for "respiratory diseases" within the current frame of the COVID-19 pandemic as an adjuvant treatment. Method: The plant selection was primarily based on species listed by the WHO and EMA, but some other herbal remedies were considered due to their widespread use in respiratory conditions. Preclinical and clinical data on their efficacy and safety were collected from authoritative sources. The target population were adults with early and mild flu symptoms without underlying conditions. These were evaluated according to a modified PrOACT-URL method with paracetamol, ibuprofen, and codeine as reference drugs. The benefits/risks balance of the treatments was classified as positive, promising, negative, and unknown. Results: A total of 39 herbal medicines were identified as very likely to appeal to the COVID-19 patient. According to our method, the benefits/risks assessment of the herbal medicines was found to be positive in 5 cases (Althaea officinalis, Commiphora molmol, Glycyrrhiza glabra, Hedera helix, and Sambucus nigra), promising in 12 cases (Allium sativum, Andrographis paniculata, Echinacea angustifolia, Echinacea purpurea, Eucalyptus globulus essential oil, Justicia pectoralis, Magnolia officinalis, Mikania glomerata, Pelargonium sidoides, Pimpinella anisum, Salix sp, Zingiber officinale), and unknown for the rest. On the same grounds, only ibuprofen resulted promising, but we could not find compelling evidence to endorse the use of paracetamol and/or codeine. Conclusions: Our work suggests that several herbal medicines have safety margins superior to those of reference drugs and enough levels of evidence to start a clinical

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Section: Hedera Helix L -Araliaceae (Leaves)mentioning

confidence: 99%

COVID-19: Is There Evidence for the Use of Herbal Medicines as Adjuvant Symptomatic Therapy?

et al. 2020

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“…oscilação das respostas em função da dinamização conforme verificado e discutido em muitas pesquisas (Kolisko & Kolisko, 1978;Andrade, 2000;Armond et al, 2005). Segundo Duarte et al (2005), o preparado homeopático isoterápico Mentrasto causa alteração no teor de óleo essencial de plantas de mentrasto (Ageratum conyzoides L.), sendo verificado o fenômeno da oscilação das respostas em função da dinamização.…”

Section: Resultado E Discussãounclassified

Crescimento e produção de cumarina em plantas de chambá (Justicia pectoralis Jacq.) tratadas com isoterápico

Andrade

Casali

Cecon

2012

Rev. bras. plantas med.

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Crescimento e produção de cumarina em plantas de chambá (Justicia pectoralis Jacq.) tratadas com isoterápico Palavras-chave: Justicia pectoralis, homeopatia, dinamizaçõesABSTRACT: Growth and production of coumarin in the plants of chambá (Justicia pectoralis Jacq.) treated with isoterapic. The studied aimed to evaluate the responses to dynamizations of Justicia isoterapic in growth and coumarin production in Justicia pectoralis. The studies were carried out at the Universidade Federal de Viçosa. The statistical design was completely randomized, with four replicates and six treatments, 24 experimental plots, one plant per pot. The treatment were dynamizations 3CH, 6CH, 12CH, 18CH, 24CH and 30CH Justicia isoterapic. The applications of the treatments begun are planting seedlings, the aerial part being sprayed, at weekly intervals. After four months of planting, the plants were harvested. Were evaluated fresh and dry matter of stem and leaves, fresh and dry matter of inflorecense, and fresh and dry matter total. Were weighed samples on 200 mg of leaves and stems of dried plants. The samples were properly stored at quimical analyses. The quantification of coumarin (1-2 benzopyrone) in the samples was done in High Resolution Liquid Chromatography. The fresh matter of leaves and stems, the fresh matter total and a production of coumarin varied as a function of dynamization of isoterapic. The results confirm the effect of homeopathics preparations in the plants demonstrating that homeopathy in vegetables even in the Equality Law has potential effect.

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“…Para umidade, o limite máximo recomendado é 14% (Fonseca et al 2010). Para cinzas totais e ácido-insolúveis, a Farmacopeia Vegetal Britânica -British Herbal Pharmacopeia (1990) recomenda limites máximos de 15% e 5% respectivamente.…”

Section: Discussionunclassified

Caracterização farmacognóstica de Piper arboreum var. arboreum e P. tuberculatum (Piperaceae)

et al. 2016

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RESUMOPiper arboreum Aubl. var. arboreum e P. tuberculatum Jacq. (Piperaceae), conhecidas como pimenta-longa, são comercializadas como produtos tradicionais fitoterápicos e, frequentemente, identificadas erroneamente, não havendo relatos sobre controle de qualidade dessas espécies. O objetivo do trabalho foi preparar e caracterizar drogas vegetais foliares e caulinares dessas espécies para estabelecer-lhes parâmetros de autenticidade botânica e grau de pureza para o controle de qualidade. Foram utilizados métodos padrões para o preparo e análises estrutural e físico-química das drogas vegetais. São caracteres diagnósticos macroscópicos para distinguir as drogas vegetais íntegras: tamanho, forma, cor, sabor, textura, características da superfície de fratura e da secção transversal e os padrões de venação foliar. São caracteres diagnósticos para distinguir as drogas vegetais pulverizadas: padrões de cutícula e cera epicuticular, tipos de tricoma e espessamento parietal dos elementos traqueais e a forma do hilo dos grãos de amido. Emergências são marcadores morfológicos chave para as drogas vegetais de P. tuberculatum. Os valores dos parâmetros físico-químicos foram similares nas drogas vegetais das espécies, exceto o de cinzas ácido-insolúveis que foi maior nas drogas vegetais caulinares de P. arboreum var. arboreum. As maiores concentrações de metais ocorreram nas drogas vegetais de P. arboreum var. arboreum. As concentrações mais elevadas foram de Al, Cu, Mn e V e as mais baixas de Cd, Co e Hg. Os resultados obtidos poderão ser utilizados como parâmetros de controle de qualidade para as drogas vegetais de ambas as espécies. PALAVRAS-CHAVE: Pimenta-longa, Produtos tradicionais fitoterápicos, Farmacognosia, Metais tóxicos, ICP-OES. Pharmacognostical characterization of Piper arboreum var. arboreum and P. tuberculatum (Piperaceae)ABSTRACT Piper arboreum Aubl. var. arboreum and P. tuberculatum Jacq. (Piperaceae), both known as "pimenta-longa", are frequently misidentified. Despite the fact that both species are sold as traditional phytotherapeutic products, there are no reports on their quality control. The aim of this study was to prepare and characterize leaf and stem herbal drugs of both species using standard methods aiming to establish parameters for botanical authentication and purity degree for their quality control. Size, shape, color, taste, texture, fracture surface and transection characteristics, and leaf venation patterns are macroscopic diagnostic characters useful to distinguish the herbal drugs when they are not powdered. The following characters are useful for diagnostic purposes of the powdered herbal drugs: cuticular and epicuticular wax patterns, types of trichomes, and wall thickening of the tracheary elements, and shape of the hilum of the starch grains. Emergences are key morphological markers for P. tuberculatum herbal drugs. Physicochemical parameter values were similar in herbal drugs of both species, except acid-insoluble ash value which was higher in the P. arboreum var. arboreum stem her...

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Justicia pectoralis Jacq: , Acanthaceae: preparation and characterisation of the plant drug including chromatographic analysis by HPLC-PDA

Cited by 22 publications

References 15 publications

COVID-19: Is There Evidence for the Use of Herbal Medicines as Adjuvant Symptomatic Therapy?

COVID-19: Is There Evidence for the Use of Herbal Medicines as Adjuvant Symptomatic Therapy?

Crescimento e produção de cumarina em plantas de chambá (Justicia pectoralis Jacq.) tratadas com isoterápico

Caracterização farmacognóstica de Piper arboreum var. arboreum e P. tuberculatum (Piperaceae)

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