Jatropha dioica, an Aztec plant with promising pharmacological properties: A systematic review

Abstract

Few pharmacological and toxicological studies have been conducted to demonstrate the usefulness and safety of using the Jatropha dioica extract. The aim of this study was to update the state of the art on the chemical composition, pharmacology, and toxicology of the species J. dioica, to find new possible applications. A search of different databases was carried out on the internet, specifically in Science Direct, PubMed, EBSCO, SCOPUS, Web of Science and Springer Link, with the keyword being "Jatropha dioica". Despite the limited results with regard to the plant toxicity, it was shown that the extract to use is innocuous. In addition, it was found that J. dioica could be employed as an antioxidant, antibiotic, antifungal, or antiviral agent. Although promising, more scientific research is needed to further validate the ethno pharmacological use of the J. dioica extracts.

Hydroethanolic extracts from Bauhinia guianensis : a study on acute toxicity in Zebrafish embryos and adults

“…Therefore, knowing the toxicity of biologically active agents can initiate the formulation of valuable and promising hypotheses for the development of new drugs (Calixto 2003 ; Agustina et al. 2020 ).…”

Antioxidant Effect of Jatropha dioica Extract on Immunoreactivity of Claudin 2 in the Kidney of Rats with Induced Diabetes

“…We resulted in the latter with the highest quantification of polyphenols. 31 Therefore, this study aimed to evaluate the effect of the hydroalcoholic extract of the JD root on the morphology of renal tissue in diabetic rats. In addition, the immunoreactivity of claudin 2 (CLDN 2) within the same tissue was evaluated since it is believed that the extracts of JD have a protective behavior on the cells.…”

Content of polyphenolic compounds, flavonoids, antioxidant activity and antibacterial activity of Jatropha dioica hydroalcoholic extracts against Streptococcus mutans

“…It owes its name to the fact that it secretes a latex that turns red when in contact with the environment. This plant contains active biological constituents such as polyphenols, flavonoids and terpenes, to which antimicrobial, antioxidant and antifungal activity have been attributed (Ramírez‐Moreno et al ., 2020; Macedo et al ., 2022).…”