Japanese research and development on metallic biomedical, dental, and healthcare materials

Niinomi, Mitsuo; Hanawa, Takao; Narushima, Takayuki

doi:10.1007/s11837-005-0076-3

Cited by 56 publications

(41 citation statements)

References 75 publications

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“…10) Shape memory -type titanium alloys exhibit superelastic behaviors because they exhibit pseudo-elastic behavior. Among these alloys, approximately 6% elastic strain was reportedly obtained in one of the Ti-NbAl system alloys by controlling its texture.…”

Section: Newly Formedmentioning

confidence: 99%

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Biologically and Mechanically Biocompatible Titanium Alloys

Niinomi

2008

Mater. Trans.

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184

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Nb, Ta, and Zr are the favorable nontoxic and allergy-free alloying elements suitable for use in titanium alloys for biomedical applications. Low-rigidity titanium alloys composed of nontoxic and allergy-free elements are receiving considerable attention. The advantage of low-rigidity titanium alloys in the healing of bone fracture and bone remodeling is successfully proven by using tibia of rabbit as a fracture model. Ni-free superelastic and shape memory titanium alloys for biomedical applications are being actively developed. The mechanical properties such as fatigue and fretting fatigue are important from the viewpoint of mechanical properties, which may be collectively referred to as mechanical biocompatibilities in the broad sense, in addition to the rigidity, i.e. Young's modulus. Bioactive surface modifications of titanium alloys for biomedical applications are very important for achieving further biocompatibility.

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Section: Newly Formedmentioning

confidence: 99%

“…Research and development of bioactive ceramic surface modifications for improving the biocompatibility of titanium alloys is also increasing 10) because titanium alloys are classified as bioinert from the view point of the patterns of osteogenesis.…”

Section: Introductionmentioning

confidence: 99%

Biologically and Mechanically Biocompatible Titanium Alloys

Niinomi

2008

Mater. Trans.

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184

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“…high strength, low elastic modulus and large plastic deformation. It has been reported that the greatest amount of bcc β phase within alloy matrix contribute to these phenomena (1) . Meanwhile, the other peculiar metallic material is also reported by rapid solid solidification form liquid metal state.…”

Section: Introductionmentioning

confidence: 99%

Characterization of Surface Properties, Osteoblast Cell Culture in Vitro and Processing with Flow-Viscosity of Ni-Free Ti-Based Bulk Metallic Glass for Biomaterials

Oak

Hwang

Park

et al. 2009

JBSE

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Ni-free type Ti-based metallic glass evaluated in this study has imposing performances for biomaterials that is based on high bulk forming ability (BFA) for implantable materials, superior specific strength, low Young's modulus as hard tissue replacements and excellent workability. Especially, surface characteristics of Ti-based bulk metallic glass for corrosion resistance exhibit a high potential for application to be used as dental implants in the oral cavity. We also made an examination of chemical stability for human cell test with osteoblasts (SaOS2) in vitro. Results of the good biocompatibility and high glass forming ability evaluated in this study are expected to increase utility value for biomedical application

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“…5) Therefore, titanium can potentially be used as a source material for the electrode of a totally implantable FES system. Fatigue properties of fine-diameter wires made of titanium materials under biological conditions should be elucidated in order to use them in an FES electrode.…”

Section: Introductionmentioning

confidence: 99%

Fatigue Behaviors of Ultra Fine Wires of β-Type and α-Type Titanium Alloys

et al. 2009

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Fatigue behaviors of ultra fine wires of -type Ti-14Mo-3Nb-1.5Zr alloy and -type Ti-10Zr alloy and -type CP (commercially pure) titanium with diameters in the range of 35-100 mm were investigated by rotating-bending fatigue testing in 1 mass% lactic acid solution maintained at 310 K. The maximum number of cycles during fatigue testing was 10 7 . The -type Ti-14Mo-3Nb-1.5Zr alloy wires showed a clear fatigue limit. On the other hand, the -type Ti-10Zr alloy wire and -type CP titanium wire did not show a clear fatigue limit, and their fatigue strengths gradually decreased with decreasing maximum bending stress. The fatigue limit of a -type Ti-14Mo-3Nb-1.5Zr alloy wire with a polished surface was greater than 50% of its tensile strength, while the fatigue limits of titanium wires with as-drawn surfaces were less than 50% of their tensile strengths. Surface defects that were introduced during the cold drawing process of the wires might act as crack origins of the fatigue fracture. Therefore, surface polishing is an effective technique for improving fatigue properties of titanium wires. The elution of metallic ions from the wires into the 1 mass% lactic acid solution was suppressed at a very low level during fatigue testing of all the investigated titanium wires.

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Japanese research and development on metallic biomedical, dental, and healthcare materials

Cited by 56 publications

References 75 publications

Biologically and Mechanically Biocompatible Titanium Alloys

Biologically and Mechanically Biocompatible Titanium Alloys

Characterization of Surface Properties, Osteoblast Cell Culture in Vitro and Processing with Flow-Viscosity of Ni-Free Ti-Based Bulk Metallic Glass for Biomaterials

Fatigue Behaviors of Ultra Fine Wires of β-Type and α-Type Titanium Alloys

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Japanese research and development on metallic biomedical, dental, and healthcare materials

Cited by 56 publications

References 75 publications

Biologically and Mechanically Biocompatible Titanium Alloys

Biologically and Mechanically Biocompatible Titanium Alloys

Characterization of Surface Properties, Osteoblast Cell Culture in Vitro and Processing with Flow-Viscosity of Ni-Free Ti-Based Bulk Metallic Glass for Biomaterials

Fatigue Behaviors of Ultra Fine Wires of &beta;-Type and &alpha;-Type Titanium Alloys

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Fatigue Behaviors of Ultra Fine Wires of β-Type and α-Type Titanium Alloys