Biologically and Mechanically Biocompatible Titanium Alloys

Niinomi, Mitsuo

doi:10.2320/matertrans.l-mra2008828

Cited by 182 publications

(111 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Among the traditional metallic biomaterials, titanium and its alloys are the most attractive due to their high specific strength, excellent biocompatibility and superior corrosion resistance [2][3][4]. However, these advantages are not enough to avoid failure risks of bone implants, because there are three main issues to be solved, stress shielding effect, biological safety and bioactivity.…”

Section: Introductionmentioning

confidence: 99%

Preparation and bioactive surface modification of the microwave sintered porous Ti-15Mo alloys for biomedical application

Zhang

Bao

et al. 2017

Sci. China Mater.

View full text Add to dashboard Cite

Biomedical porous Ti-15Mo alloys were prepared by microwave sintering using ammonium hydrogen carbonate (NH 4 HCO 3 ) as the space holder agent to adjust the porosity and mechanical properties. The porous Ti-15Mo alloys are dominated by β-Ti phase with a little α-Ti phase, and the proportion of α and β phase has no significant difference as the NH 4 HCO 3 content increases. The porosities and the average pore sizes of the porous Ti-15Mo alloys increase with increase of the contents of NH 4 HCO 3 , while all of the compressive strength, elastic modulus and bending strength decrease. However, the compressive strength, bending strength and the elastic modulus are higher or close to those of natural bone. The surface of the porous Ti-15Mo alloy was further modified by hydrothermal treatment, after which Na 2 Ti 6 O 13 layers with needle and flake-like clusters were formed on the outer and inner surface of the porous Ti-15Mo alloy. The hydrothermally treated porous Ti-15Mo alloy is completely covered by the Ca-deficient apatite layers after immersed in SBF solution for 14 d, indicating that it possesses high apatiteforming ability and bioactivity. These results demonstrate that the hydrothermally treated microwave sintered porous Ti15Mo alloys could be a promising candidate as the bone implant.

show abstract

Section: Introductionmentioning

confidence: 99%

Preparation and bioactive surface modification of the microwave sintered porous Ti-15Mo alloys for biomedical application

Zhang

Bao

et al. 2017

Sci. China Mater.

View full text Add to dashboard Cite

show abstract

“…The inertness seems to make Ti and Ti-alloy a perfect material for implants. However, ill effects such as osteomalacia, allergic reaction and peripheral neuropathy were still found in Ti-alloy implanted bodies, which were likely due to the release of aluminium and vanadium from the alloy [1,3,46]. The development of new generation of Ti-alloys (b-titanium alloys) is now in progress.…”

Section: Titanium-based Alloymentioning

confidence: 99%

State of the art of bioimplants manufacturing: part I

Kang

Fang

2018

Adv. Manuf.

View full text Add to dashboard Cite

Bioimplants are becoming increasingly important in the modern society due to the fact of an aging population and associated issues of osteoporosis and osteoarthritis. The manufacturing of bioimplants involves an understanding of both mechanical engineering and biomedical science to produce biocompatible products with adequate lifespans. A suitable selection of materials is the prerequisite for a long-term and reliable service of the bioimplants, which relies highly on the comprehensive understanding of the material properties. In this paper, most biomaterials used for bioimplants are reviewed. The typical manufacturing processes are discussed in order to provide a perspective on the development of manufacturing fundamentals and latest technologies. The review also contains a discussion on the current measurement and evaluation constraints of the finished bioimplant products. Potential future research areas are presented at the end of this paper.

show abstract

“…Titanium and its alloys are widely used in biomedical applications, because of their low specific weight, low elastic modulus, high specific strength, excellent biocompatibility, and high corrosion resistance [1,2]. Pure titanium (CP Ti), Ti-6Al-4V alloys, TiNi alloys, and Ti6Al-7Nb alloys have been successfully employed in clinical applications [3].…”

Section: Introductionmentioning

confidence: 99%

Preparation and Characterization of Ti-10Mo Alloy by Mechanical Alloying

Gao

Luo

et al. 2012

Metallogr. Microstruct. Anal.

View full text Add to dashboard Cite

In the present study, Ti-10Mo alloy was fabricated by mechanical alloying and subsequently consolidated by powder metallurgy techniques. The structural evolution of the powder blends with various milling durations, and the sintered alloys with different holding times, were characterized by x-ray diffraction, scanning electron microscopy, and light microscopy. The results revealed that the size of powder particles decreased with increasing milling time. In addition, only the sintered alloy using powders milled for 5 h exhibited both a-phase and b-phase. When the milling time increased to greater than 40 h, TiN phase gradually formed, which suppressed the a-phase to b-phase transformation. Furthermore, the effects of the sinter holding time on the Vickers hardness and the corrosion behavior of Ti-10Mo alloys was also investigated. The results showed that the Vickers hardness increased with increasing sinter holding time; after sintering the alloy for 5 h, the samples exhibited acceptable corrosion resistance.

show abstract

Biologically and Mechanically Biocompatible Titanium Alloys

Cited by 182 publications

References 25 publications

Preparation and bioactive surface modification of the microwave sintered porous Ti-15Mo alloys for biomedical application

Preparation and bioactive surface modification of the microwave sintered porous Ti-15Mo alloys for biomedical application

State of the art of bioimplants manufacturing: part I

Preparation and Characterization of Ti-10Mo Alloy by Mechanical Alloying

Contact Info

Product

Resources

About