“…This study revealed an association of energy drink to a QT shortening and increase in a HR percent augmentation, which is consistent with a growing concern of the suspected arrhythmogenic effect of these beverages, which is supported by some case reports of energy drink-related congenital long QT syndrome [57], cardiac arrest [58,59], QTc interval prolongation [60], Brugada syndrome [61] and atrial fibrillation [62,63]. Caffeine is one of the main components that increases QT variability during sleep, which suggests that excessive caffeine intake results in adverse cardiovascular reactions in vulnerable subjects [64].…”