Isolation of two antigens from Trypanosoma evansi that are partially responsible for its cross-reactivity with Trypanosoma vivax

Camargo, Rocío; Uzcanga, Graciela L.; Bubis, José

doi:10.1016/j.vetpar.2004.01.022

Cited by 24 publications

(22 citation statements)

References 30 publications

(44 reference statements)

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“…In addition, the farm owners in this study reported occurrence of a large amount of leaches during the rainy season, which could increase the risk of T. evansi transmission since these worms could be vectors and reservoirs of this protozoan (CAMARGO, 2004). Presence of wild reservoirs, such as capybaras and coatis, is frequently reported by locals from the properties visited during this study.…”

Section: Discussionmentioning

confidence: 79%

“…The transmission of T. evansi occurs through blood-sucking vectors, especially tabanids and flies of the genus Stomoxys, hematophagous bats (Desmodus rotundus), and, probably, ticks and leaches (CAMARGO et al, 2004;CARREIRA, 2005). In South America, wild animals, especially capybaras (Hidrochoerus hidrochaeris) and ring-tailed coatis (Nasua nasua), are considered important T. evansi reservoirs.…”

Section: Introductionmentioning

confidence: 99%

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Reemerging of natural infection by Trypanosoma evansi in horses in Arari, Marajó Island, Brazil

et al. 2016

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Section: Discussionmentioning

confidence: 79%

Section: Introductionmentioning

confidence: 99%

Reemerging of natural infection by Trypanosoma evansi in horses in Arari, Marajó Island, Brazil

et al. 2016

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“…Além disso, o surto iniciou no verão, época com maior número desses insetos. T. evansi pode ser transmitido mecanicamente por insetos hematófagos das famílias Tabanidae e Stomoxidae (Stomoxis niger, S. taeniatus e S. calcitrans) (Hoare 1972), entretanto, é interessante observar que carrapatos têm sido sugeridos como vetores na transmissão de T. evansi e T. vivax (Camargo et al 2004). Isso levanta a possibilidade de um carrapato estar envolvido na transmissão de T. evansi de capivaras para os eqüinos.…”

Section: Discussão Discussão Discussão Discussão Discussãounclassified

Surtos de tripanossomíase por Trypanosoma evansi em eqüinos no Rio Grande do Sul: aspectos epidemiológicos, clínicos, hematológicos e patológicos

et al. 2005

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Additionally, around 80 mares were sent to Farm A to be bred. Of those, 66 became ill and 56 died after being returned to their farms of origin. Twenty one horses clinically affected by the disease were observed. Clinical signs included loss of weight (despite voracious appetite), lethargy, incoordination and instability of hindlimbs, atrophy of the large muscles of the hindlimbs, muscle weakness and paleness of mucosae. Specimens of T. evansi were detected in the blood drawn from four affected horses. Normocytic normochromic anemia with PCVs ranging from 15 to 31%, leucocytosis due to lymphocytosis associated to large atypical lymphocytes was observed in several affected horses. High levels of antibodies against T. evansi were detected in the serum of six horses from Farm A. Eight horses presented encephalic neurological signs such as circling, ataxia, blindness, excitation, falls, listlessness, proprioception deficits and head tilt. One horse assumed a "dogseating position". Necropsy findings included muscle atrophy, enlargement and lymphoid hyperplasia of the spleen and lymphnodes, edema and softening of the white and grey matter of the brain. Histologically, an overwhelming necrotizing panencephalitis was observed in the seven horses with encephalic signs. This panencephalitis was characterized by marked edema, demyelination and necrosis and perivascular infiltrates of 6-10 layers of lymphocytes and plasm cells affecting both the white and gray matter. Several plasm cells in the inflammatory infiltrate contained numerous eosinophilic globules in their cytoplasm (Mott cells). Similar histological lesions were observed in the spinal cord of the horse with the "dog-seating position". The brains of five horses with the encephalic signs were submitted to immunohistochemistry stain by the streptavidinbiotin technique. In all of those five brains moderate to abundant specimens of T. evansi in the perivascular spaces and neuropile were marked by the specific antibody. Epidemiological, clinical, hematological, and pathological aspects of equine trypanosomiasis caused by T. evansi are discussed.

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“…Another possibility for positive serological reactions would be crossed reactions with other trypanosomes endemic for cattle in the Pantanal region, such as T. theileri and T. evansi. Nevertheless, the first species does not show crossed reaction with T. vivax (Luckins 1977), but the latter Trypanosoma species has antigens that induce antibodies which display cross-reactions with T. vivax (Camargo et al 2004). However, the reduced level of cross-reactions in the ELISA test used with sera of animals infected with T. evansi (Madruga et al 2006) and the low prevalence of this haemoprotozoan in the Brazilian and Bolivian Pantanal (Franke et al 1994, Dávila et.…”

Section: Interaction Of Factors Related To Environment and Host Determentioning

confidence: 99%

Trypanosoma vivax infection dynamics in a cattle herd maintained in a transition area between Pantanal lowlands and highlands of Mato Grosso do Sul, Brazil

Martins¹,

Madruga²,

Koller³

et al. 2008

Pesq. Vet. Bras.

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relevant economical impact due to weight loss, abortion and mortality. Cattle moved from the Pantanal to adjacent areas of this ecosystem for breeding and fattening is a common feature. Therefore an epidemiological study on breeding cows in the transition area between Pantanal lowland and adjacent highlands of Mato Grosso do Sul was performed to determine the T. vivax infection dynamics and outbreak risk. Three experimental groups were formed: Group 1 consisted of cows parasitologically negative by the Woo test and in the enzyme-linked immunosorbent assay for T. vivax antibody detection (Tv-ELISA-Ab); Group 2 parasitologically negative and positive in the Tv-ELISA-Ab; and in Group 3 cows were parasitologically positive and with positive reactions in the Tv-ELISAAb. During 24 months, the cows' dislodgment between the above established groups was monitored by Woo test and Tv-ELISA-Ab exams. The tabanid population was also monitored and the highest number occurred during the rainy season. Although parasitemias were detected only in the first four samplings of the experimental period, the cows could be considered as trypanotolerant, because no clinical signs were observed. Despite the higher T. vivax incidence during the dry season, no disease symptoms were seen. Even though T. vivax epidemiological situation in the herd was characterized as endemic with seasonal variation, the probability of outbreaks was null within the conditions of the study.

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Isolation of two antigens from Trypanosoma evansi that are partially responsible for its cross-reactivity with Trypanosoma vivax

Cited by 24 publications

References 30 publications

Reemerging of natural infection by Trypanosoma evansi in horses in Arari, Marajó Island, Brazil

Reemerging of natural infection by Trypanosoma evansi in horses in Arari, Marajó Island, Brazil

Surtos de tripanossomíase por Trypanosoma evansi em eqüinos no Rio Grande do Sul: aspectos epidemiológicos, clínicos, hematológicos e patológicos

Trypanosoma vivax infection dynamics in a cattle herd maintained in a transition area between Pantanal lowlands and highlands of Mato Grosso do Sul, Brazil

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