Isolation of mimengoside B, a triterpenoid saponin from Buddleja madagascariensis

Emam, Ahmed M.; Moussa, Ayman S.; Faure, Robert; Élias, Riad; Balansard, G.

doi:10.1016/s0378-8741(97)00095-0

Cited by 6 publications

(4 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…One example of such a prodrug is a derivative of 1, mimengoside B, consisting of a sugar moiety linked to an aglycon which is a derivative of 1. It is believed to be the cause of the therapeutic properties of the infusion of leaves of Buddleja madagascariensis, a species related to Buddleja saligna used in the treatment of asthma, coughs and bronchitis (Emam et al, 1997). Other previous studies have found oleanolic acid-containing saponins to possess broad-spectrum anti-fungal activity (Favel et al, 1994).…”

Section: Resultsmentioning

confidence: 99%

Anti-mycobacterial activity of five plant species used as traditional medicines in the Western Cape Province (South Africa)

Bamuamba

Gammon

Meyers

et al. 2008

Journal of Ethnopharmacology

View full text Add to dashboard Cite

Section: Resultsmentioning

confidence: 99%

Anti-mycobacterial activity of five plant species used as traditional medicines in the Western Cape Province (South Africa)

Bamuamba

Gammon

Meyers

et al. 2008

Journal of Ethnopharmacology

View full text Add to dashboard Cite

“…Their structures were identified as crocusatin M (1), 8 crocusatin C (2), 9 acacetin (3), 10 lariciresinol (4), 11 pinoresinol (5), 11 syringaresinol (6), 12 mimengoside B (7), 13,14 and songarosaponin A (8)…”

Section: Resultsmentioning

confidence: 99%

Chemical Constituents fromBuddleja officinalisand Their Inhibitory Effects on Nitric Oxide Production

Park

Lee

et al. 2016

Nat Prod Sci

View full text Add to dashboard Cite

-Bioactivity-guided fractionation of a methanolic extract of Buddleja officinalis led to the isolation of two monoterpenes, crocusatin M (1), crocusatin C (2), a flavonoid, acacetin (3), three lignans, lariciresinol (4), pinoresinol (5), and syringaresinol (6), and two triterpenoidal saponins, mimengoside B (7) and songarosaponin A (8). The structures of isolates were identified based on 1D-, 2D-NMR, and MS data analysis. All isolates were tested for their inhibition on LPS-induced NO production in RAW 264.7 cells. As a result, mimengoside B (7) and songarosaponin A (8) showed a mild inhibitory activity of NO production.

show abstract

“…It was branched from about 10-15 cm above the ground level. The whole plant was covered with glandular and eglandular trichome responsible for reduction in water lose making the plants drought resistance (Figure 1) (Emam et al, (1997). Leaves were simple, lanceolate showed the opposite decussate phyllotaxy (Fig.…”

Section: Vegetative Charactersmentioning

confidence: 99%

“…can reproduce from stem fragments and is capable of resprouting quickly after a fire (Flora Base, 2010). The species was identified by mimengoside B, a triterpenoid saponin, in its leaves and is useful to treat asthma, coughs, and bronchitis and for dyeing clothes (Emam et al, 1997). The leaves show diuretic activity due to presence of the flavonoid and iridoid content (Houghton & Mensah,1999).…”

Section: Introductionmentioning

confidence: 99%

Morphological, anatomical and preliminary phytochemical characterization of Buddleja madagascariensis Lam.

Dobriyal

Guleri

Singh

2021

View full text Add to dashboard Cite

Buddleja madagascariensis Lam. is a perennial invasive shrub distributed in tropical and sub-tropical regions of the world. The present study was conducted on morphological, anatomical and phytochemical characterization of Buddleja madagascariensis and the results revealed that plant height varied from about 188-191 cm, and the whole plant was covered with trichome which may be glandular and eglandular and unicellular or, multicellular. Inflorescence was terminal and axillary in position, thyrsoid panicle. Anatomical and histo-chemical studies of the transverse section of various parts of the plant revealed the presence of steller tissues, starch in cortical and pith region. Phytochemical analysis of the crude extract showed the presence of carbohydrates, proteins, saponins, flavonoids, phenolic compounds and tannins. But alkaloids, glycosides and free amino acids were absent. Thus, characterization of plants on the basis of these parameters could be used as tools to distinguish the crude drugs of plants from adulterants, used in the preparation of traditional medicines and used as diagnostic keys. Also, it is useful in the future for revealing the importance of plants and phytochemical resources for the conservation of resources.

show abstract

Isolation of mimengoside B, a triterpenoid saponin from Buddleja madagascariensis

Cited by 6 publications

References 2 publications

Anti-mycobacterial activity of five plant species used as traditional medicines in the Western Cape Province (South Africa)

Anti-mycobacterial activity of five plant species used as traditional medicines in the Western Cape Province (South Africa)

Chemical Constituents fromBuddleja officinalisand Their Inhibitory Effects on Nitric Oxide Production

Morphological, anatomical and preliminary phytochemical characterization of Buddleja madagascariensis Lam.

Contact Info

Product

Resources

About