Isolation of an oleanane-type saponin active from<i>Bellis perennis</i>through antitumor bioassay-guided procedures

Karakaş, Fatma Pehlivan; Şöhretoğlu, Didem; Liptaj, Tibor; Štujber, Michal; Türker, Arzu Uçar; Marák, Jozef; Çalış, İhsan; Yalçın, Funda Nuray

doi:10.3109/13880209.2013.874461

Cited by 13 publications

(8 citation statements)

References 18 publications

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“…Bellis perennis L. (Asteraceae), called Nvwangju, is an herbaceous perennial plant known as a traditional wound herb. It has been used for the treatment of bruises, broken bones, wounds, headaches, the common cold, stomach aches, eye diseases, eczema, skin boils, gastritis, diarrhea, bleeding, rheumatism, inflammation, and infections of the upper respiratory tract in traditional medicine [ 10 ].…”

Section: Introductionmentioning

confidence: 99%

Analysis of Floral Volatile Components and Antioxidant Activity of Different Varieties of Chrysanthemum morifolium

Liu

Aobulikasimu·Nuerbiye

Cheng

et al. 2017

Molecules

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This study investigated the volatile flavor compounds and antioxidant properties of the essential oil of chrysanthemums that was extracted from the fresh flowers of 10 taxa of Chrysanthemum morifolium from three species; namely Dendranthema morifolium (Ramat.) Yellow, Dendranthema morifolium (Ramat.) Red, Dendranthema morifolium (Ramat.) Pink, Dendranthema morifolium (Ramat.) White, Pericallis hybrid Blue, Pericallis hybrid Pink, Pericallis hybrid Purple, Bellis perennis Pink, Bellis perennis Yellow, and Bellis perennis White. The antioxidant capacity of the essential oil was assayed by spectrophotometric analysis. The volatile flavor compounds from the fresh flowers were collected using dynamic headspace collection, analyzed using auto thermal desorber–gas chromatography/mass spectrometry, and identified with quantification using the external standard method. The antioxidant activities of Chrysanthemum morifolium were evaluated by DPPH and FRAP assays, and the results showed that the antioxidant activity of each sample was not the same. The different varieties of fresh Chrysanthemum morifolium flowers were distinguished and classified by fingerprint similarity evaluation, principle component analysis (PCA), and cluster analysis. The results showed that the floral volatile component profiles were significantly different among the different Chrysanthemum morifolium varieties. A total of 36 volatile flavor compounds were identified with eight functional groups: hydrocarbons, terpenoids, aromatic compounds, alcohols, ketones, ethers, aldehydes, and esters. Moreover, the variability among Chrysanthemum morifolium in basis to the data, and the first three principal components (PC1, PC2, and PC3) accounted for 96.509% of the total variance (55.802%, 30.599%, and 10.108%, respectively). PCA indicated that there were marked differences among Chrysanthemum morifolium varieties. The cluster analysis confirmed the results of the PCA analysis. In conclusion, the results of this study provide a basis for breeding Chrysanthemum cultivars with desirable floral scents, and they further support the view that some plants are promising sources of natural antioxidants.

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Section: Introductionmentioning

confidence: 99%

Analysis of Floral Volatile Components and Antioxidant Activity of Different Varieties of Chrysanthemum morifolium

Liu

Aobulikasimu·Nuerbiye

Cheng

et al. 2017

Molecules

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“…Bauhinia variegate possessed anticancer effect against Dalton's ascitic lymphomas, skin papilloma, human epithelial larynx cancer, human breast cancer (HBL-100) cells and N-nitrosodiethylamine induced experimental liver tumor in rats (91)(92)(93)(94)(95) . Bellis perennis showed cytotoxicity in potato disc tumor induction bioassay (96)(97)(98) . Betula alba possessed anticancer effects against neuroblastoma, rabdomyosarcoma-medulloblastoma, glioma, thyroid, breast, lung, colon carcinoma, leukemia, multiple myeloma, ovarian carcinoma, cervical carcinoma, glioblastoma multiforme, A431 (skin epidermoid carcinoma), A2780 (ovarian carcinoma), HeLa (cervix adenocarcinoma) and MCF7 (breast adenocarcinoma), liver metastatic murine colon 26-L5 carcinoma cells, WI-38 fibroblast cells, VA-13 malignant tumor cells and K562 tumor cell line (99)(100)(101)(102)(103)(104) .…”

Section: Plants With Anticancer Effectsmentioning

confidence: 99%

Natural sources as promising future anticancer therapies - A review

Thuwaini¹

2022

GSC Biol. and Pharm. Sci.

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“…También se ha reportado su actividad antiinflamatoria, antipirética, antiespasmódica, astringente, depurativa, diurética, expectorante, mucolítica, disolvente, tónica y vulneraria (Duke et al, 2002). Se han identificado en sus flores saponinas triterpénicas de tipo oleanano, flavonoides y poliacetilenos en extractos (Avato et al, 1997;Costa Marques et al, 2013;Morikawa et al, 2015) y se ha demostrado su actividad antihiperlipidémica, antitumoral, reductora de la glucosa en sangre, fotoprotectora e inmunomoduladora en los queratinocitos de la piel, reductora de la pérdida de sangre posparto, promotora de la síntesis de colágeno en fibroblastos dérmicos, antioxidante, inhibidora de la acetilcolinesterasa y antimicrobiana (Avato et al, 1997;Oberbauma et al, 2005;Morikawa et al, 2010;Costa Marques et al, 2013; Pehlivan Karakas et al, 2014;Morikawa et al, 2015;Haselgrübler et al, 2018;Souza de Carvalho et al, 2021). Sturms et al, 1905: t. 9;Cabrera, 1971: 19, fig.…”

Section: Usos Y Propiedadesunclassified

Primer registro de la especie exótica Bellis perennis (Asteraceae, Astereae) en la Provincia de Buenos Aires, centro de Argentina

Vercelli

Scaramuzzino

Goyenetche

2022

LIL

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Bellis perennis (Asteraceae, Astereae), especie de uso ornamental y maleza de cultivos agrícolas, se encuentra naturalizada en diferentes partes del mundo. Hasta el momento, en Argentina solo había sido registrada en el extremo sur, en las provincias patagónicas de Chubut y Tierra del Fuego e Islas del Atlántico sur, incluyendo las islas Malvinas. Se comunica la presencia de esta especie exótica en la Provincia de Buenos Aires, en los partidos de Azul y Olavarría, constituyendo el primer registro para el centro de Argentina en su área pampeana. Se describe, se ilustra con fotografías y se presentan nuevas observaciones respecto a su distribución y hábitat.

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Isolation of an oleanane-type saponin active fromBellis perennisthrough antitumor bioassay-guided procedures

Abstract: Through antitumoral bioassay-guided fractionation and isolation procedures, 1 was isolated from the active fraction of B. perennis. The detailed NMR data of compound 1 is given for the first time.

Cited by 13 publications

References 18 publications

Analysis of Floral Volatile Components and Antioxidant Activity of Different Varieties of Chrysanthemum morifolium

Analysis of Floral Volatile Components and Antioxidant Activity of Different Varieties of Chrysanthemum morifolium

Natural sources as promising future anticancer therapies - A review

Primer registro de la especie exótica Bellis perennis (Asteraceae, Astereae) en la Provincia de Buenos Aires, centro de Argentina

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