Morusalba is a fast-growing shrub or medium-sized tree with a straight, cylindrical trunk. Medicinally, whole plants, leaves, fruits, branches, and roots have been employed. Google Scholar, PubMed, Scopus, and Web of Science were used to search for relevant material on the phytochemical components and pharmacologic and mechanism of action of the Morus alba. This was reviewed to assess important updates about Morus alba. The fruits of Morus alba have traditionally been used as an analgesic, anthelmintic, antibacterial, anti-rheumatic, diuretic, hypotensive, hypoglycemia, purgative, restorative, sedative tonic, and blood stimulant. Various plant parts were used as a cooling, sedating, diuretic, tonic, and astringent agent to treat nerve disorders. The plant contained tannins, steroids, phytosterols, sitosterol, glycosides, alkaloids, carbohydrates, proteins, and amino acids, as well as saponins, triterpenes, phenolics, flavonoids, benzofuran derivatives, anthocyanins, anthraquinones, glycosides, vitamins, and minerals. Previous pharmacological research identified antimicrobial, anti-inflammatory, immunological, analgesic, antipyretic, antioxidant, anti-cancer, antidiabetic, gastrointestinal, respiratory, cardiovascular, hypolipidemic, anti-obesity, dermatological, neurological, muscular, and protecting effects. This study looked at Morus alba’s traditional uses, chemical components, and pharmacological effects.
Cancer is the second leading cause of death worldwide. The alternative natural therapies are required as they considered to have less toxic side effects compared to current chemotherapy. In the current review Web Science, PubMed, Scopus and Science Direct, were searched to provide information about medicinal plants that have shown anticancer activity against various forms of cancer.
In the current work, the widespread of IgG and IgM antibodies to TORCH (Toxoplasma gondii, Rubella virus, Cytomegalovirus, Herpes simplex virus) agents were investigated in women with Bad Obstetric History (BOH). The study was conducted on 120 aborted women age (15-40) years who visited Public Health Center in Ibn -Ghazwan and Basra hospital in Basra city, from October 2019 to March 2020. Forty normal women (age matched) were taken as control. IgG and IgM Abs of infections, were tested with used (TORCH) kit IgG and IgM ELISA and VIDAS technique ELFA (Enzyme Linked Fluorescent Assay) by used Vidas instrument (BioMerieux /France).it is automated immunoassay system. The results showed that the overall of TORCH infection was (75%). This rate contributed the following rates (94.2%, 75.8%, 48.3%, 30.8% and 15%) for Rubella, HSV -1, T. gondii, CMV and HSV-2 respectively. Relationship between aborted women age distribution was important especially women aging from 36-40 years with strongly significant variation between age groups of HSV-2 only (P˂ 0.003).Regarding frequency of TORCH IgG positive according to gestational periods of pregnancy, it did not appear any statistical significant variations between the trimester groups of all TORCH IgG infections, except CMV IgG infection (P˂ 0.04). Residential distribution with type of infection according IgM Antibodies shows that most infection occurred in urban area in all agents except in Toxoplasmainfections, which formed 82.7% in rural area.
The prevalence of obesity was worldwide increase in the last 60 years. Obesity represented one of the public health problems, it markedly increased the incidence of many diseases: fatty liver, type 2 diabetes, hypertension, ischemic heart diseases, sleep apnea, osteoporosis, dementia, tumors and many other disorders. Recent reviews showed that many medicinal plants possesses anti-obesity effect. In the current review, PubMed, Web Science, Science Direct, Research gate, Academia.edu and Scopus were searched to verify the hypolipidemic and anti-obesity activities of Morus alba.
Background and aims: Angina pectoris is the discomfort felt when the heart muscle does not receive enough oxygen. The definition of stable angina is the presence of symptoms only with exertion. Chest pain, or its angina equivillant, is a defining feature, and it is relieved by rest or nitroglycerin when exercise is ceased. Often, this is one of the first symptoms or warning indications of underlying coronary disease. The proinflammatory state is believed to aggravate endothelial dysfunction by activating endothelial cells, releases cytokines and chemokines, which may be crucial in the atherosclerotic plaque formation which is the primary cause of angina pectoris. We studied the value of some cytokines and cardiac markers as a diagnostic and follow up markers in patients with stable angina. Methodology: The study was carried out on 50 patients diagnosed with stable angina pectoris, who visited Nasiriya Heart Center throughout the period from December 2021 to April 2022, and 20 age matched healthy person. IL-1β, IL-5, IL-6, IL-8 were assayed at baseline (hospital admission), 1 day and 1 week post-PCI by an enzyme-linked immunosorbent assay (ELISA). In addition, Troponin I (cTnl) was determined by using monoclonal cTnI-specific antibody.
Background and aims: Angina pectoris is the discomfort felt when the heart muscle does not receive enough oxygen. The definition of stable angina is the presence of symptoms only with exertion. Chest pain, or its angina equivillant, is a defining feature, and it is relieved by rest or nitroglycerin when exercise is ceased. Often, this is one of the first symptoms or warning indications of underlying coronary disease. The proinflammatory state is believed to aggravate endothelial dysfunction by activating endothelial cells, releases cytokines and chemokines, which may be crucial in the atherosclerotic plaque formation which is the primary cause of angina pectoris. We studied the value of some cytokines and cardiac markers as a diagnostic and follow up markers in patients with stable angina. Methodology: The study was carried out on 50 patients diagnosed with stable angina pectoris, who visited Nasiriya Heart Center throughout the period from December 2021 to April 2022, and 20 age matched healthy person. IL-1β, IL-5, IL-6, IL-8 were assayed at baseline (hospital admission), 1 day and 1 week post-PCI by an enzyme-linked immunosorbent assay (ELISA).
Sickle cell anemia (SCD) is one of the important health problems in Basrah, southern Iraq. which is probably the most common known hereditary blood disorder. patients with sickle cell disorders often suffer from chronic hemolytic anemia, which causes bone marrow hyperplasia too. The present study aimed to evaluate the severity of bone impairment in different types of sickle cell anemia in patients. Patients with SCA (n=120) 60 males and 60 females were on follow up in the Basra center for Hereditary Blood Disease, who were included in this study and age and sex matched healthy persons (n=60) as controls. biomarkers had important role in many biological processes. measure serum levels of different biomarkers such as; BCTx, BSAP, CRP, DPD, IGF-1, OT, TRACP-5b, FER, IGFBPT, Intact (iPTH), Ostase, PINP and serum Ca+. Using Kruskal-Wallis test as statistical test, markers in sickle cell anemia and control groups. The results showed were statistical significant differences among the groups of patients included in this study and control group for all the biomarkers that were measured (P=0.0001). Conclusion: The compound heterozygous(Hb SC Hb S/β-thal, ) are less severe than the homozygous genotype (HbSS).
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