Isolation of Acinetobacter species and their antimicrobial resistance pattern in an Intensive Care Unit (ICU) of a tertiary care hospital in Dhaka, Bangladesh

Nahar, Azizun; Anwar, Shaheda; Saleh, Ahmed Abu; Miah, Md. Ruhul Amin

doi:10.3329/bjmm.v6i1.19352

Cited by 6 publications

(6 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Another study inHFRCMCH in 2013 showed most isolates were from blood followed by respiratory tract 17 . In BSMMU, 50% Acinetobacter species were isolated from blood (central venous catheter and peripheral blood) which was similar to our study 18 . Another study conducted in Karachi showed 44% of organisms were solely from blood 19 .In BIRDEM hospital; Acinetobacter species were isolated from Blood 18.4%, urine 4.7% and respiratory secretion 40.9% 18 .…”

Section: Introductionsupporting

confidence: 89%

“…In BSMMU, 50% Acinetobacter species were isolated from blood (central venous catheter and peripheral blood) which was similar to our study 18 . Another study conducted in Karachi showed 44% of organisms were solely from blood 19 .In BIRDEM hospital; Acinetobacter species were isolated from Blood 18.4%, urine 4.7% and respiratory secretion 40.9% 18 . Acinetobacter colonization has been reported from the respiratory tract (41%) followed by urinary tract (25.5%), wound (20%) and blood (12.7%) in a study conducted in India 20 .…”

Section: Introductionsupporting

confidence: 89%

“…High level of resistance was recorded in Ampicilin 92% and low level was in imepenem about 55%. A study conducted in BSMMU showed Ceftriaxone resistance was 100%, Amikacin resistance was 68.4% and imepenem resistance was 66.7% 18 . A study from BIRDEM hospital in 2010 reported ceftriaxone resistance was 98.2%, amikacin resistance was 81.4%, and imepenem resistance was 72.4% 23.…”

Section: Resultmentioning

confidence: 99%

See 2 more Smart Citations

Isolation of Acinetobacter species and their antimicrobial resistance pattern in a tertiary care hospital in Dhaka, Bangladesh

Ferdous¹,

Murshed²,

Shahnaz³

et al. 2017

Bangladesh J Med Microbiol

View full text Add to dashboard Cite

Acinetobacter species are important opportunistic and nosocomial pathogens capable of causing both community and health careassociated infections (HAIs). The clinical specimens obtained from patients admitted in Holy Family Red Crescent Medical College and Hospital (HFRCMCH) from July 2013 to June 2015. All laboratory works were performed in department of microbiology and immunology of HFRCMCH. The infection rate was maximum in blood (67.7%) followed by urine (12.9%), tracheal aspirate (8.8%) and wound swab (3.32%). Most of the Acinetobacter were isolated from Intensive care unit (ICU) and Neonatal intensive care unit ( NICU). Acinetobacter displayed higher resistance to many antibiotics like Ampicillin which showed 96% resistance, Ceftriaxone 72%, Amikacin 72%, Imipenem 55%, Meropenem 60%, Tetraclycline 64%, Ciprofloxacin 60% and Cotrimoxazole showed 38% resistance. In conclusion, there was a high resistant rate to available and common antibiotics. It seems that infection control strategies may help to control the evolving problem of Acinetobacter infections and prevent an epidemic nosocomial life threatening infections.Bangladesh J Med Microbiol 2016; 10 (1): 18-21

show abstract

Section: Introductionsupporting

confidence: 89%

Section: Introductionsupporting

confidence: 89%

Section: Resultmentioning

confidence: 99%

See 1 more Smart Citation

Isolation of Acinetobacter species and their antimicrobial resistance pattern in a tertiary care hospital in Dhaka, Bangladesh

Ferdous¹,

Murshed²,

Shahnaz³

et al. 2017

Bangladesh J Med Microbiol

View full text Add to dashboard Cite

show abstract

“…Many authors have reported A. lwoffii as a drug susceptible organism as compared to A. baumannii. [36][37][38] All isolates of S. maltophilia were resistant towards ceftazidime, cefepime, imipenem and meropenem. However, it was found that only 26.6% isolates were resistant to piperacillintazobactum and 13.3% towards gentamicin and amikacin.…”

Section: Resultsmentioning

confidence: 99%

Prevalence and antibiogram of nonfermenting gram negative bacilli isolates obtained from various clinical samples in a tertiary care hospital, Bathinda, Punjab, India

Kaur¹,

Gill²,

Singh³

2018

Int J Res Med Sci

View full text Add to dashboard Cite

Background: Non-fermenting gram-negative bacilli (NFGNB) have emerged as important healthcare associated pathogens in recent years. Infections caused by these bacteria are almost always secondary to some predisposing factors in patients such as burns, prolonged antimicrobial therapy, immunosuppression etc. The Objectives of the study was to be carried out with an objective to identify NFGNB upto genus and species level and study their antimicrobial sensitivity/ resistance pattern so that empiric therapy could be selected accordingly.Methods: A total of 2261 clinical samples were collected from patients admitted in ICU and different wards of the hospital. All samples were processed according to standard microbiological procedures. Identification of NFGNB upto genus and species level was done by various biochemical tests. Antimicrobial susceptibility testing was done by Kirby Bauer disc diffusion method results were interpreted in accordance with clinical laboratory standards institute guidelines.Results: In this study, 365 NFGNB were obtained accounting for their prevalence of 16.1%. P. aeruginosa was the commonest NFGNB isolated in this study accounting for 52.6%, A. baumannii was the second common NFGNB isolated (31.7%). Other NFGNB isolates were obtained with a lesser frequency. P. aeruginosa isolates were highly sensitive to polymyxin B and colistin followed by imipenem. Most of the A. baumannii isolates were multidrug resistant.Conclusions: This study gives an alarming sign towards high prevalence of multi drug resistant NFGNB in our hospital. Therefore, improved antibiotic stewardship and strict protocols for hand washing need to be implemented to prevent emergence and spread of multidrug resistant NFGNB in health care settings.

show abstract

“…In Bangladesh, AB was isolated from a third of clinical samples from the intensive care unit (ICU) of a university hospital in 2010, and two-thirds of the isolates were resistant to carbapenems (106). In a seven-center study on Gram-negative bloodstream infections conducted between March 2009 and February 2010 in Sri Lanka, approximately 40% of 71 AB isolates were resistant to the carbapenems (107).…”

Section: South Asiamentioning

confidence: 99%

Carbapenem-Resistant Acinetobacter baumannii and Enterobacteriaceae in South and Southeast Asia

et al. 2017

View full text Add to dashboard Cite

SUMMARY Carbapenem-resistant Gram-negative bacteria, in particular the Acinetobacter baumannii-calcoaceticus complex and Enterobacteriaceae, are escalating global public health threats. We review the epidemiology and prevalence of these carbapenem-resistant Gram-negative bacteria among countries in South and Southeast Asia, where the rates of resistance are some of the highest in the world. These countries house more than a third of the world's population, and several are also major medical tourism destinations. There are significant data gaps, and the almost universal lack of comprehensive surveillance programs that include molecular epidemiologic testing has made it difficult to understand the origins and extent of the problem in depth. A complex combination of factors such as inappropriate prescription of antibiotics, overstretched health systems, and international travel (including the phenomenon of medical tourism) probably led to the rapid rise and spread of these bacteria in hospitals in South and Southeast Asia. In India, Pakistan, and Vietnam, carbapenem-resistant Enterobacteriaceae have also been found in the environment and community, likely as a consequence of poor environmental hygiene and sanitation. Considerable political will and effort, including from countries outside these regions, are vital in order to reduce the prevalence of such bacteria in South and Southeast Asia and prevent their global spread.

show abstract

Isolation of Acinetobacter species and their antimicrobial resistance pattern in an Intensive Care Unit (ICU) of a tertiary care hospital in Dhaka, Bangladesh

Cited by 6 publications

References 0 publications

Isolation of Acinetobacter species and their antimicrobial resistance pattern in a tertiary care hospital in Dhaka, Bangladesh

Isolation of Acinetobacter species and their antimicrobial resistance pattern in a tertiary care hospital in Dhaka, Bangladesh

Prevalence and antibiogram of nonfermenting gram negative bacilli isolates obtained from various clinical samples in a tertiary care hospital, Bathinda, Punjab, India

Carbapenem-Resistant Acinetobacter baumannii and Enterobacteriaceae in South and Southeast Asia

Contact Info

Product

Resources

About