Isolation and immunisation studies of a canine parco-like virus from dogs with haemorrhagic enteritis

Abstract

A newly recognised canine parvo like virus was isolated from faeces of dogs with haemorrhagic enteritis. Cell cultures from several species were susceptible to it. Virus infected cells could be demonstrated by staining with fluorescent antibody reagents (prepared against canine virus or feline panleucopenia virus) or by haemagglutination with pig or rhesus monkey red blood cells. Inhibition of haemagglutination by specific antiserum prepared in specific-pathogen-free beagles provided a convenient method for viral identification. Experimental inoculation of specific-pathogen-free beagles resulted in elevated body temperatures and caused lymphopenia lasting one to three days. Feline panleucopenia virus vaccines protected dogs against challenge with virulent canine parvo-like virus.

Evidence for Recombination Between Feline Panleukopenia Virus and Canine Parvovirus Type 2

“…They infect many animal species including man and cause a variety of diseases that are sometimes fatal for newborn animals. Canine parvovirus type 2 (CPV), one of the feline parvovirus (FPV) subspecies, is a parvovirus that first appeared in the late 1970s as an emerging pathogen [1]. In the early 1980s, the first CPV (antigenic type 2: CPV-2) disappeared from the field having been replaced by a new antigenic variant designated CPV-2a, and another antigenic variant CPV-2b appeared soon afterwards.…”

Viral type characterization and clinical aspects of canine parvovirus in naturally infected dogs in São Paulo State, Brazil

“…clinical conditions and whose symptoms include vomiting, diarrhea, prostration and anorexia (Appel et al 1979, Potgieter et al 1981, MacIntire & Smith-Carr 1997, Sellon et al 2005. However, clinical diagnosis of CPV-2 is misleading, as there are other etiologic agents responsible for gastroenteritis in dogs.…”

Isolation and characterization of canine parvovirus type 2c circulating in Uruguay

“…It rapidly spread worldwide, causing a new enteric and myocardial disease in dogs (APPEL et al, 1979). Few years after its emergence CPV-2 was completely replaced by two new antigenic variants designated as CPV-2a and CPV-2b (PARRISH et al, 1985;1988).…”

“…Canine parvovirus (CPV-2) is the most significant viral cause of canine enteritis over the age of 2 months and was first isolated in 1978 as an emerging pathogen (APPEL et al, 1979). It rapidly spread worldwide, causing a new enteric and myocardial disease in dogs (APPEL et al, 1979).…”