Isolation and Antibacterial Activity Test of Lauric Acid from Crude Coconut Oil (Cocos nucifera L.)

Nitbani, Febri Odel; Jumina,; Siswanta, Dwi; Solikhah, Eti Nurwening

doi:10.1016/j.proche.2016.01.021

Cited by 59 publications

(34 citation statements)

References 4 publications

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“…10 Furthermore the presence of lauric acid in coconut oil can inhibit the growth of Staphylococcus aureus, Bacillus cereus, Salmonella typhimurium and Escherichia coli at a concentration of 5% when compared with Ciprofloxacin. 33 In 2006, Ósk Thorgeirsdóttir et al investigated the effects of monocaprin acid as a denture disinfecting agent and he reported an increased antimicrobial activity against Candida when it is topically applied. 34 Likewise, a study done in Nigeria, evaluated 100% concentration of coconut oil which showed an inhibitory effect on some species of Candida when compared to fluconazole.…”

Section: Studies Related To the Effects Of Coconut Oil On Systemic Hementioning

confidence: 99%

Role of Coconut Oil Pulling On Oral Health – An Overview

Seher¹,

Hosein²,

Ahmed³

2018

J Pak Dent Assoc

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Oil pulling (extended mouth swishing) is a long-established ancient herbal practice that includes swishing of oil for a prolonged period in the mouth for maintaining better oral environment and providing systemic healthy effects. There are number of edible oils which are used in this therapy but the scientific evidence is limited. Recent literature shows that coconut is one of the most popular pulling oil amongst all. Coconut oil is effective against many oral and systemic conditions and also in bacterial and fungal infections because of the presence of lauric acid which is a major fatty acid component. This article reviews the literature regarding the mechanism, composition, benefits and scientific clinical studies related to coconut oil pulling therapy on oral health. KEY WORDS: oil pulling, coconut oil, lauric acid, monolaurin HOW TO CITE: Saher F, Hosein M, Ahmed J. Role of coconut oil pulling on oral health -an overview. J Pak Dent Assoc 2018;27(3):94-99.

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Section: Studies Related To the Effects Of Coconut Oil On Systemic Hementioning

confidence: 99%

Role of Coconut Oil Pulling On Oral Health – An Overview

Seher¹,

Hosein²,

Ahmed³

2018

J Pak Dent Assoc

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“…The excellent A similar finding after hydrolysing VCO with lipolytic Geotrichum candidum was observed by Khoramnia et al (2013), suggesting that the enzymatic reaction had improved the medium-chain fatty acids contents in VCO and its antimicrobial activity. This finding is essential as, lauric acid has been reported to be the main compound from the MCFAs contributed to the excellent antimicrobial activity (Nakatsuji et al, 2009;Yang et al, 2009;Huang et al, 2014;Salleh et al, 2014;Chang et al, 2015;Ma et al, 2016;Nitbani et al, 2016;Sheela et al, 2017).…”

Section: Minimum Inhibitory Concentration (Mic) Of Avco and Vcomentioning

confidence: 98%

Fatty Acid Evaluation and Antimicrobial Activity of Virgin Coconut Oil and Activated Virgin Coconut Oil on Streptococcus mutans

Haron¹,

Mukhtar²,

Omar³

et al. 2019

AOS

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For decades, coconut oil was reported to possess a broad spectrum of antimicrobial activity due to its abundant fatty acid's contents. Streptococcus mutans (S. mutans) has been strongly implicated as the main etiological factor in dental caries. Regardless of the ongoing medical advances, the therapeutic resources for dental caries remain ineffectual, and this has led to renewed interest in using virgin coconut oil (VCO) as a possible choice for dental caries control. In this study, the ability of VCO and activated virgin coconut oil (AVCO) combatting cariogenic S. mutans ATCC 25175 has been evaluated. Fatty acids contents were compared through gas chromatography-mass spectrum (GC-MS) analysis, and their antimicrobial activity was determined using disc diffusion and minimum inhibitory concentration (MIC) test. From the GC-MS analysis, AVCO (59%) was found to have a slightly higher medium-chain fatty acids (MCFA) as compared to VCO (54.1%), and the long-chain fatty acids (LCFA) contents in VCO (45.9%) was found to be higher than AVCO (41%). Interestingly, S. mutans ATCC 25175 was found to be susceptible towards AVCO (MIC: 6.24 mg/ml) and resistance towards VCO in vitro. The excellent antimicrobial activity of AVCO as a result from (i) the release of individuals fatty acids after activation of VCO by lipase digestion and (ii) the present of MCFA and LCFA that are significant in antimicrobial activity. Further study can be designed to specifically examine the activity of individuals fatty acids present in oils against S.mutans virulence genes/protein using molecular dynamic assessment.

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“…Beberapa manfaat dari asam linoleat di antaranya adalah untuk mencegah Alzheimer, menurunkan kolesterol dan menurunkan tekanan darah (Cole dan Frautschy, 2006;Rizzo;1986;Terres et al, 2008). (Muniyan dan Gurunathan, 2015;Nitbani et al, 2016).…”

Section: Pendahuluanunclassified

Mengungkap Senyawa pada Nata De Coco sebagai Pangan Fungsional

Anam

2019

JIPHP

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Nata adalah selulosa ekstraseluler yang dihasilkan dari aktiivitas bakteri Acetobacter xylinum dalam proses fermentasi, dan merupakan salah satu makanan kesehatan yang kaya akan serat. Nata yang paling umum ditemukan adalah nata de coco dengan media fermentasi air kelapa. Faktor-faktor dominan dalam pembuatan nata adalah ketersediaan nutrisi (karbon dan nitrogen), derajat keasaman dan media fermentasi yang digunakan. Penentuan kualitas terbaik media air kelapa yang digunakan, penentuan konsentrasi nitrogen dan sukrosa yang ditambahkan serta kondisi pH optimum akan menghasilkan nata yang maksimal.Penelitian ini bertujuan untuk mencari kualitas terbaik pada fermentasi dalam proses pembuatan nata de coco, dan mengetahui senyawa fungsional yang terdapat pada nata de coco sebagai pangan fungsional. Hasil pengujian analisa sampel nata de coco menggunakan Gas chromatography–mass spectrometry (GC-MS) menunjukkan senyawa yang sangat bermaaf bagi kesehatan tubuh manusia. Sepuluh besar senyawa fungsional yag terdapat pada nata de coco yaitu: Benzeneacetic Acid sebagai anti fungal dan scavenger. Hexadecanoid Acid memiliki efek anti-inflamasi, anti bakteri dan anti fungi. 22-Hydroxyhopane, Tetradecanoic Acid yang mempunyai aktivitas antimikroba dan antifungal. 9-Octadecanoid Acid, ρ-Cresol memiliki aktivitas antioksidan. 9-Octadecenamide berfungsi untuk mencegah Alzheimer, menurunkan kolesterol dan menurunkan tekanan darah, Senyawa fungsional yang lain diantaranya (Z), Phenol, 4-(2-aminoethyl), Pentadecanoic Acid, 1-Heptadecanecarboxylic acid. Komposisi kimia nata de coco dihasilkan kadar air 95%. abu 0,35% dan protein 0,45%. Penelitian menunjukkan peningkatkan produksi nata dengan kualitas yang baik sesuai persyaratan standar yang telah ditetapkan dan mempunyai senyawa senyawa yang bermanfaat sebagai pangan fungsional yang bermanfaat bagi kesehatan.

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Isolation and Antibacterial Activity Test of Lauric Acid from Crude Coconut Oil (Cocos nucifera L.)

Cited by 59 publications

References 4 publications

Role of Coconut Oil Pulling On Oral Health – An Overview

Role of Coconut Oil Pulling On Oral Health – An Overview

Fatty Acid Evaluation and Antimicrobial Activity of Virgin Coconut Oil and Activated Virgin Coconut Oil on Streptococcus mutans

Mengungkap Senyawa pada Nata De Coco sebagai Pangan Fungsional

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