“…These include Hepatitis C virus infection, liver cirrhosis, tuberculosis, AIDS, post-transplant immunodeficiency, intravenous drug abuse, chronic alcoholism, androgenic steroid therapy, corticosteroid therapy, oral contraceptives, advanced malignancies including hematologic malignancies, and hemodialysis. To date, spontaneous rupture of the spleen due to peliosis has been previously described few times in the literature (7)(8)(9)(10)(11)(12)(13)(14)(15)(16). Peliosis of the spleen has characteristic gross appearance of cystic blood-filled spaces with well-defined margins, commonly involving the red pulp, distributed in a sporadic, clustered, or disseminated pattern.…”