Isolated epidermolytic acanthoma. A solitary tumor showing granular degeneration

Multiple Spreading Epidermolytic Acanthomas of the Genital and Perigenital Skin

“…Disseminated epidermolytic acanthomas are exceptionally reported with less than 10 cases up to now in the literature [1,[3][4][5][6][7]. The originality of our case relies upon the clinical pattern of eruptive scrotal papules spreading on the perineum, groins and the buttocks.…”

“…The originality of our case relies upon the clinical pattern of eruptive scrotal papules spreading on the perineum, groins and the buttocks. Only 1 among the 7 patients reported initially by Shapiro and Baraf [1] presented with multiple lesions on the scrotum. To our knowledge, the present case is the first with the peculiar clinical pattern of multiple extensive perigenital papules.…”

“…Epidermolytic acanthoma is an acquired benign tumour that usually presents as a solitary, verrucous papule or plaque, approximately 1 cm in diameter [1]. The trunk, scrotum or the light-exposed skin of middle-aged people are the usually affected sites.…”

“…The histopathological sections reveal characteristic features of epidermolysis, hyperkeratosis, parakeratosis and acanthosis [2]. Although usually solitary, clinical variants of this condition have been documented including disseminated forms which affect the scrotum, trunk, scalp and lower extremities [1,[3][4][5][6][7].…”

Nevus comedonicus with Epidermolytic Hyperkeratosis

“…In this case the EH oc curred not only in the follicular epithelium Table I. Occurrence of EH in other dermatoses Bullous ichthyosiform erythroderma [7,8] Nevus unius lateris [9,10] Ichthyosis hystrix [10] Keratoderma palmariset plantaris [11] Solitary epidermolytic acanthoma [12] Disseminated epidermolytic acanthoma [13,14] Epidermolytic leukoplakia [15,16] Acrosyringial epidermolytic papulosis neviformis [17] I ncidental finding in a variety acquired solitary skin le sions [18,19] but also in the sebaceous ducts, and was as sociated with dyskeratotic cells and corps ronds in some specimens. Barsky et al [4] reported this variety of nevus comedonicus in 4 patients, 1 of whom had been previously described by Montgomery [20].…”