Isolamento de Candida no esfregaço cérvico-vaginal de mulheres não gestantes residentes em área ribeirinha do Estado do Maranhão, Brasil, 2012

Sá, Márcia Caroline Nascimento; Sousa, Haigle Reckziegel de; Amaro, Cláudia Simone Oliveira; Pinheiro, Dirce Nascimento; Oliveira, Michele Moreira Martins de; Pinheiro, Maria da Conceição Nascimento

doi:10.5123/s2176-62232014000100003

Cited by 5 publications

(9 citation statements)

References 19 publications

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“…However, this difference in age between the group of women with VVC and the otherwise healthy group was not detected by other authors 1, 17, 19, 23. Similarly, use of hormonal contraception or intrauterine devices, vaginal pH ≤ 4.5, pregnancy and HIV infection, which are considered as risk factors for the development of VVC3, 5, 20, 26 were not significantly associated with VVC infection in our study. This discrepancy may be due to the small number of women with VVC in our study ( n = 35), which does not allow for a robust statistical analysis for risk factors for the disease.…”

Section: Discussioncontrasting

confidence: 76%

“…However, it is below the 69% found by Holanda and co-workers 17 in a study conducted in Natal, the 47.9% found by Andrioli and co-workers 1 in Bahia, the 42.7% described by Sá and co-workers 20 in Maranhão and the 39.6% found by Dias and co-workers 7 in Mato Grosso. Considering that this disease is opportunistic, this discrepancy may be related to several factors related to the etiologic agent, the species distribution and/or virulence of the strains, the immune status of the host, or the environment, which influences the maintenance of temperature and humidity conducive to fungal proliferation 1, 12, 20, 21…”

Section: Discussionmentioning

confidence: 60%

“…from vaginal mucosa can be explained by cultural habits of different regions, especially in regard to hygiene practices, as this factor is directly related to self-contamination because the yeast belongs to the normal gastrointestinal tract microbiota 3, 17, 18. On the other hand, similar studies in northeastern Brazil show fungal isolation in women with and without vulvovaginitis of up to 46% 1, 17, 19, 20. It is assumed that other factors besides those mentioned above may explain the high prevalence of Candida spp.…”

Section: Discussionmentioning

confidence: 99%

“…Moreover, Álvares and co-workers 4 state that the vaginal microbiota of black women has a lower incidence of bacterial species, and there would thus be a decrease in natural defenses against fungal growth, predisposing them to infection by Candida spp 4, 20…”

Section: Discussionmentioning

confidence: 99%

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Prevalence of Candida spp. in cervical-vaginal samples and the in vitro susceptibility of isolates

Brandolt

Klafke

Gonçalves

et al. 2017

Brazilian Journal of Microbiology

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Vulvovaginal candidiasis (VVC) is an infection of the genital mucosa caused by different species of the genus Candida. Considering the lack of data on this topic in the south of Brazil, this study aimed to assess the prevalence of Candida spp. in the cervical-vaginal mucosa of patients treated at a university hospital in southern Rio Grande do Sul, as well as the etiology and the susceptibility of the isolates against fluconazole, itraconazole, miconazole and nystatin. Samples were collected at the gynecology clinic of the Federal Hospital of the University of Rio Grande, and the isolates were identified using phenotypic and biochemical tests. The susceptibility analysis was performed according to the CLSI M27-A2 protocol. Of the 263 patients included, Candida spp. was isolated in 27%, corresponding to a prevalence of approximately 15% for both VVC and colonization. More than 60% of the isolates were identified as Candida albicans; C. non-albicans was isolated at a rate of 8.6% in symptomatic patients and 14.3% in asymptomatic patients. The prevalence of resistance against fluconazole and itraconazole was 42% and 48%, respectively; the minimal inhibitory concentration of miconazole ranged from 0.031 to 8 μg/mL, and that of nystatin ranged from 2 to >16 μg/mL. The high rate of resistance to triazoles observed in our study suggests the necessity of the association of laboratory exams to clinical diagnosis to minimize the practice of empirical treatments that can contribute to the development of resistance in the isolates.

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Section: Discussioncontrasting

confidence: 76%

Section: Discussionmentioning

confidence: 60%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Prevalence of Candida spp. in cervical-vaginal samples and the in vitro susceptibility of isolates

Brandolt

Klafke

Gonçalves

et al. 2017

Brazilian Journal of Microbiology

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“…Regarding the association between the presence of Candida and the age of the participants recently survey did not observe this relationship, since the average age of cultures positive for Candida was 37 years old, ranging from 14 to 65 years old [34]. Other research found that the higher frequency of patients with positive cultures was between 14 and 46, and showed no association between the identified species of yeast and the age of the patients [35].…”

Section: Concentrationsmentioning

confidence: 83%

Vaginal Yeasts and the Antifungal Action of Red Propolis Extract

et al. 2015

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Introduction:Vulvovaginitis is an inflammatory process that affects the vulva, vagina and cervix, most of the times of infectious cause. Vulvovaginal candidiasis is the second most frequent cause in Brazil, in Europe ranks first. Candida spp can be found in the vagina up to 20% of asymptomatic women.Objective: Understanding the occurrence of vaginal yeasts and evaluating the antifungal action of a red propolis extract.Method: This is a clinical study in vitro with vaginal secretion samples collected from 197 patients treated at the Health Center Frei Damiao in Patos-PB, Brazil. The species were identified using a chromogenic medium CHROMagar Candida®. At the end, the antifungal activity of the red propolis extract in four different concentrations was observed: 25%, 50%, 75% and 100%, by test disc Agar diffusion. The study was approved by the Research Ethics Committee of the Federal University of Campina Grande, CAAE 35203614.8.0000.5575. Results:Of the samples analyzed other species identified by the medium used were the most prevalent corresponding to 59.8%, followed by C. albicans, with 21.7%. The antifungal activity was observed in 81.25% of the tested samples. According to the average and standard deviation of the inhibition zone of the four concentrations, the one that presented the smallest variation was the concentration at 50%, followed by concentration to 75%. Conclusions:The results of this research showed that there was antifungal action of red propolis extract, since occurred inhibition in 81.25% of the analyzed samples. However did not show clearance regarding this action, since positivity tendency was not growing by increasing or decreasing the concentration of propolis extract.

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Fatores associados à presença de Candida spp. em amostras de fluído vaginal de mulheres residentes em comunidades quilombolas

Batista

Oliveira

Aragão

et al. 2020

Medicina (Ribeirao Preto Online)

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Objetivo: Investigar a frequência e fatores associados à detecção de Candida spp. em fluido vaginal de mulheres residentes em uma comunidade quilombola. Materiais e Método: Um estudo transversal foi conduzido com 177 mulheres residentes em uma comunidade quilombola no Nordeste do Brasil. Foram coletados dados sociodemográficos, hábitos de vida, saúde geral e saúde reprodutiva. O material coletado na região do colo do útero foi submetido a exame citopatológico. Amostras de fluido vaginal foram coletadas para a análise microbiológica. Os testes Qui-quadrado, exato de Fisher e modelos de Regressão Logística foram utilizados na análise estatística. Resultados: Foi detectado Candida spp. em 28,9% das amostras. A espécie mais frequente nos casos positivos foi a Candida albicans (49%), seguida da Candida krusei (39,2%). Após o ajustamento, observou-se que mulheres com idade igual ou maior que 50 anos apresentaram maior chance da detecção de Candida spp. no fluido vaginal (OR ajustada = 3,46; IC95% = 1,68-7,12), enquanto as mulheres com queixa de corrimento vaginal apresentaram uma chance menor de detecção de Candida spp. (OR ajustada = 0,29; IC95% = 0,11-0,78). Conclusão: Os achados sugerem uma elevada detecção de Candida spp. no fluido vaginal entre mulheres residentes em comunidades quilombolas, o que sinaliza a necessidade do planejamento de medidas para prevenção e rastreamento de caso de candidíase vulvovaginal neste grupo populacional. Além disso, a presença de Candida spp. foi mais elevada em mulheres a partir da quinta década de vida, menor nas mulheres com queixas de corrimento vaginal.

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Isolamento de Candida no esfregaço cérvico-vaginal de mulheres não gestantes residentes em área ribeirinha do Estado do Maranhão, Brasil, 2012

Cited by 5 publications

References 19 publications

Prevalence of Candida spp. in cervical-vaginal samples and the in vitro susceptibility of isolates

Prevalence of Candida spp. in cervical-vaginal samples and the in vitro susceptibility of isolates

Vaginal Yeasts and the Antifungal Action of Red Propolis Extract

Fatores associados à presença de Candida spp. em amostras de fluído vaginal de mulheres residentes em comunidades quilombolas

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