Isoflavones from the roots and stems of Nicotiana Tabacum and their anti-tobacco mosaic virus activities

Isoflavones from the leaves of Nicotiana tabacum and their anti-tobacco mosaic virus activities

“…1, and the 1 H and 13 C NMR data of 1-3 are listed in Table 1. The known compounds were identified as 7-hydroxy-3 0 ,4 0 ,5 0 ,6-tetramethoxy-isoflavone (4) (Chen et al, 2012b), genistein (5) (Iinuma et al, 1994) and 2 0 ,4 0 ,5 0 ,6,7-pentamethoxyisoflavone (6) (Delcioarques et al, 1998).…”

“…Since certain isoflavones exhibit potential anti-TMV activity (Chen et al, 2012b;Gao et al, 2012b;Hu et al, 2013b), compounds 1-3 were tested for their anti-TMV activities. The inhibitory activities of compounds 1-6 against TMV replication were tested using the half-leaf method (Hu et al, 2013a).…”

“…In addition, N. tabacum is also used as insecticides, anesthetics, diaphoretics, sedatives, and emetic agents in Chinese folklore medicines because of its useful chemical compounds (Kuang and Lu, 2005;Rodgman and Perfetti, 2008). Previous phytochemical studies of tobacco have shown the presence of sesquiterpenes Yang et al, 2013), alkaloids (Braumann et al, 1990;Wei et al, 2005), lignans Gao et al, 2012a), flavonoids (Chen et al, , 2012bYe et al, 2012), phenylpropanoids (Leng et al, 2014;Tan et al, 2011), chromanones (Mou et al, 2012;Yang et al, 2014), Biphenyls (Shang et al, 2014a), phenolic amides (Shang et al, 2014b), isocoumarins (Shang et al, 2015), and the homologous. However, the previous reports on occurance of isoflavones in the Solanaceae family are still rather unusual (Arthan et al, 2002;Chen et al, 2012b;Sini and Devi., 2004;Ye et al, 2012).…”

Biphenyls from Nicotiana tabacum and their anti-tobacco mosaic virus

“…In addition, N. tabacum is also used as insecticides, anesthetics, diaphoretics, sedatives, and emetic agents in Chinese folklore medicines because it contains many useful chemical compounds [1,3]. Previous investigation of this species led to the discovery of a number of new compounds by our groups, which were found to exhibit various bioactivities, such as anti-HIV-1, anti-TMV, and cytotoxicity [4][5][6][7][8][9]. In continuing efforts to utilize N. tabacum and identify bioactive natural products, the phytochemical investigation of the leaves of Honghua Dajinyuan (a variety of N. tabacum) led to the isolation of five new (1)(2)(3)(4)(5) and five known (6-10) biphenyls, of which compound 1 possessed a seldom reported 6-carbons unit (C-7, C-8, C-9, C-10, C-11, C-12) in biphenyls.…”

A New Phenolic Compound from the Stems of Flue-Cured Tobacco and Its Anti-Tobacco Mosaic Virus Activity

“…In addition to being used in cigarette industry, N. tabacum is also used as insecticide, anesthetic, diaphoretic, sedative and emetic agents in Chinese folklore medicine because of it containing many useful chemical compounds 1,[3][4][5] . In previous work, a number of bioactive compounds, such as terpenoids [6][7][8] , alkaloids 9,10 , lignans 11,12 , flavonoid 13 , phenyl-propanoids 14 and the homologous, were isolated from this plant. The stems and roots of N. tabacum are big amount of byproduct in tobacco planting and are normally used as organic fertilizer.…”