Is there an association between liver type fatty acid binding protein and severity of preeclampsia?

Uzunlar, Özlem; Üstün, Yaprak Engin; Özyer, Şebnem; Danışman, Nuri; Çandar, Tuba; Keskin, Senem M.; Mollamahmutoğlu, Leyla

doi:10.1007/s00404-014-3540-x

Cited by 2 publications

(1 citation statement)

References 25 publications

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“…HELLP syndrome can be measured by elastosonography acoustic radiation force impulse (ARFI) [116]. For the diagnosis of HELLP syndrome, elevated levels of ET-1, M30, and Angs-1 and -2 appear as promising apoptotic-associated biomarkers where serum M30 levels have the benefit of being the most promising test for predictive or differential diagnosis of HELLP syndrome in PE patients [117]. D-dimers can also be as biomarkers in fibrin formation and degradation where levels were significantly increased in Sudanese women with PE, with hemostatic abnormalities [118].…”

Section: Situmorang and Ilyasmentioning

confidence: 99%

Study of Preeclampsia in Placenta, Kidney, and Hepatic Diseases

Situmorang

Ilyas

2018

Asian J Pharm Clin Res

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Preeclampsia (PE) have a high risk of pregnancy disorder and can cause liver and kidney disease. PE is a dangerous disease in Indonesia with a high risk of cardiovascular death. PE has biomarkers such as proteinuria, blood pressure, dipstick test, renin-angiotensin system, adipsin, calcium/ creatinine (Cr) ratio, albumin/Cr ratio, and uric acid. Apoptosis occurs in the placenta’s PE, where trophoblasts invade and overhaul the uterine spiral artery in the epidermal growth factor signaling system, and the expression of miRNA in PE is targeting genes in a variety of pathophysiological processes can cause kidney and hepatic disease. In this review, we will discuss role of HSP, miRNA, Immunology cell and the risk of kidney and hepatic disease of patient of Preeclampsia.

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Section: Situmorang and Ilyasmentioning

confidence: 99%

Study of Preeclampsia in Placenta, Kidney, and Hepatic Diseases

Situmorang

Ilyas

2018

Asian J Pharm Clin Res

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Effects of vitamin C, vitamin E, and molecular hydrogen on the placental function in trophoblast cells

Guan

Guo

et al. 2015

Arch Gynecol Obstet

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High levels of antioxidant vitamins C and E may have significant detrimental effects on placental function, as reflected by decreased cell viability and secretion of hCG; and placental immunity, as reflected by increased production of TNF-a. Meanwhile hydrogen showed no such effects on cell proliferation and TNF-α expression, but it could affect the level of hCG, indicating hydrogen as a potential candidate of antioxidant in the management of preeclampsia (PE) should be further studied.

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Is there an association between liver type fatty acid binding protein and severity of preeclampsia?

Abstract: Maternal serum LFABP level appears to be correlated with the severity of the preeclampsia and can be used to confirm the diagnosis.

Cited by 2 publications

References 25 publications

Study of Preeclampsia in Placenta, Kidney, and Hepatic Diseases

Study of Preeclampsia in Placenta, Kidney, and Hepatic Diseases

Effects of vitamin C, vitamin E, and molecular hydrogen on the placental function in trophoblast cells

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