Is there a concordance between carotid and penile cavernosal artery intima-media thickness in patients with erectile dysfunction?

Abstract

This study aimed to investigate the predictive accuracy of carotid and cavernosal Doppler ultrasound findings for discriminating patients with vasculogenic erectile dysfunction (ED). Fifty patients with complaints of ED were included. B-mode ultrasound of bilateral carotid arteries were performed and peak systolic velocity (PSV), end-diastolic velocity (EDV) and intima-media thickness (IMT) values were measured. Afterwards, corresponding values of cavernosal arteries were obtained by penile color duplex ultrasonography (P-CDU). Of total 50 patients, 29 (58%) were included in vasculogenic ED group and 21 (42%) in non-vasculogenic ED group according to P-CDU findings. There was a significant difference between groups for cavernosal IMT (P ¼ 0.012) but not for carotid IMT (P ¼ 0.601). When patients were reclassified according to carotid IMT values (IMT of the first group o0.9 mm and the second X0.9 mm), carotid PSV and EDV values were different (P ¼ 0.033 and 0.018, respectively). Cavernosal PSV and EDV displayed no difference (P ¼ 0.816 and 0.123) while cavernosal IMT and percent change of cavernosal caliper were significantly different (P ¼ 0.014 and 0.018). Carotid PSV and EDV successfully mirrored respective measurements in cavernosal artery. However, carotid IMT failed to demonstrate such a correlation. Cavernosal IMT seems promising as an additional tool in the evaluation of cavernosal function.

Evaluation of penile cavernosal artery intima-media thickness in patients with erectile dysfunction. A new parameter in the diagnosis of vascular erectile dysfunction. Our experience on 59 cases

“…When patients were reclassified according to carotid IMT values (IMT of the first group < 0.9 mm and the second > = 0.9 mm), carotid PSV and EDV values were different (P = 0.033 and 0.018, respectively). Cavernosal PSV and EDV displayed no difference (P = 0.816 and 0.123) while cavernosal IMT and percent change of cavernosal caliper were significantly different (P = 0.014 and 0.018) (46). Caretta performed a high magnification ultrasonographic study in order to compare functional and morphological parameters of the cavernous artery to PSV and their relation with penile and systemic atherosclerosis (47).…”

A szexuális funkciózavar és a metabolikus szindróma kapcsolata

“…Egy munkacsoport a MSval társult ED-ban szenvedők 70,3%-ában igazolta a pénisz cavernosus artériájának csökkent véráramlását és 59,3%-ukban a szisztémás érrendszer kóros állapotát [36]. Más kutatók is megállapították Doppler-ultrahangvizsgálattal, hogy az ED-ban szenvedő férfiak felében az ED vascularis eredetű [37]. Ezekben a betegekben a pénisz cavernosus artériájának fala megvastagodott, és egyúttal a nyaki artériában is kimutatható volt a véráramlás csökkenése.…”

Cardiovascular Disease Prevention in Men with Vascular Erectile Dysfunction: The View of the Preventive Cardiologist

“…Men with vascular erectile dysfunction have higher carotid intimaemedia thicknesses than individuals with erectile dysfunction of other causes or healthy controls. 54,55 In this context, carotid intimaemedia thickness has been proposed as a tool for the further risk assessment of patients with vascular erectile dysfunction who are considered at intermediate risk. 30,33 Nevertheless, studies have shown that the prognostic value of carotid intimaemedia thickness beyond traditional risk factors in the general population is modest, 56 and the 2013 American College of Cardiology/American Heart Association risk assessment guideline recommends against "measuring carotid intima-media thickness in routine clinical practice for risk assessment for a first atherosclerotic cardiovascular disease event" 28 (class III, level B).…”