Is primiparity a risk factor for advanced maternal age pregnancies?

Kalaycı, Hakan; Özdemir, Halis; Alkaş, Didem; Çok, Tayfun; Tarım, Ebru

doi:10.1080/14767058.2016.1211633

Cited by 15 publications

(14 citation statements)

References 25 publications

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“…In our study, the frequency of preeclampsia/gestational hypertension was significantly higher in primiparas. Our results are compatible with those from other literature reports ( 19 , 23 , 24 ). However, Chan and Lao found no significant difference between the two groups ( 18 ).…”

Section: Discussionsupporting

confidence: 94%

“…Placenta previa was reported to be more common in advanced maternal age pregnancies ( 15 , 26 ). Our study found no significant difference between primiparas and multiparas in the frequency of placenta previa, in accordance with the results by Kalayci et al ( 23 ).…”

Section: Discussionsupporting

confidence: 93%

“…Fetal loss is reported to be more common in advanced maternal age multiparous women ( 19 , 27 ), but some studies show it to be more common in primiparas ( 23 ). We showed no significant difference between primiparas and multiparas in this outcome.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

The effect of parity on obstetric and perinatal outcomes in pregnancies at the age of 40 and above: a retrospective study

GENÇ¹,

EMEKLİOGLU>²,

Cıngıllıoğlu³

et al. 2021

Croat Med J

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Section: Discussionsupporting

confidence: 94%

Section: Discussionsupporting

confidence: 93%

See 1 more Smart Citation

The effect of parity on obstetric and perinatal outcomes in pregnancies at the age of 40 and above: a retrospective study

GENÇ¹,

EMEKLİOGLU>²,

Cıngıllıoğlu³

et al. 2021

Croat Med J

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“…Furthermore, recent enormous changes in work and society have been reflected in women’s desire to develop their careers, obtain financial security and built a stable relationship with their partner before becoming mothers. Higher educational level among females led to a better knowledge and awareness of different types of contraception and, together with greater access to birth control methods, constitutes another factor responsible for an increase in maternal age [8], [9].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Pregnancy Outcomes at Advanced Maternal Age

Radoń-Pokracka

Adrianowicz

Płonka

et al. 2019

Open Access Maced J Med Sci

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AIM: The study aimed to investigate the association between advanced maternal age (AMA) and the risk of adverse maternal, perinatal and neonatal outcomes about parity in singleton pregnancies.METHODS: We retrospectively analysed 950 women who gave birth in the Department of Obstetrics and Perinatology of the University Hospital in Kraków for six months (between 1st January and 30th June 2018). The patients were divided into 3 groups according to their age (30-34 years old, 35-39 years old and over 40 years old). Each of these groups was subsequently subdivided into 2 groups depending on parity (primiparae and multiparae). Maternal, perinatal and neonatal outcomes were compared between the groups and the subgroups.RESULTS: Comparison of the three age groups revealed that advanced maternal age might constitute a predisposing factor for preterm birth, caesarean section and large for gestational age (LGA). From these parameters, statistical significance was reached in case of greater risk of LGA (OR = 2.17), caesarean section (OR = 2.03) and elective C-section (OR = 1.84) in women over 40 years old when compared to the patients aged 30-34. Furthermore, AMA increases the risk of postpartum haemorrhage (OR = 6.43). Additionally, there is a negative correlation between maternal age and gestational age at delivery (R = -0.106, p < 0.05).CONCLUSIONS: Advanced maternal age can undoubtedly be associated with several adverse perinatal outcomes. At the same time, the risk of perinatal complications begins to increase after the age of 35 but becomes significant in women aged ≥ 40.

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“…Thus, primiparous women with AMA are considered to be at highest risk of complications [2,8]. Primiparous women with AMA have a greater risk of pre-eclampsia [16], HELLP syndrome [16], instrumental birth [2,5]; urgent cesarean [2,5], fetal growth retardation [16], low birthweight [2,8] and perinatal death [5,8,16].…”

Section: Introductionmentioning

confidence: 99%

Association between advanced maternal age and maternal and neonatal morbidity: A cross-sectional study on a Spanish population

et al. 2019

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Background and objectiveOver recent decades, a progressive increase in the maternal age at childbirth has been observed in developed countries, posing a health risk for both women and infants. The aim of this study was to analyze the association between advanced maternal age (AMA) and maternal and neonatal morbidity.Material and methodsA cross-sectional study of 3,315 births was conducted in the north of Spain in 2014. We compared childbirth between women aged 35 years or older, with a reference group of women aged between 24 and 27 years. AMA was categorized based on ordinal ranking into 35–38 years, 39–42 years, and >42 years to estimate a dose-response pattern (the older the age, the greater the risk). As an association measure, crude and adjusted Odds Ratios (OR) were estimated by non-conditional logistic regression and 95% Confidence Intervals (95%CI) were calculated.ResultsRepeated abortions were more common among women of AMA in comparison to pregnant women aged 24–27 years (reference group): adjusted OR = 2.68; 95%CI (1.52–4.73). A higher prevalence of gestational diabetes was also observed among women of AMA, reaching statistical significance when restricted to first time mothers: adjusted OR = 8.55; 95%CI (1.12–65.43). In addition, the possibility of an instrumental delivery was multiplied by 1.6 and the possibility of a cesarean by 1.5 among women of AMA, with these results reaching statistical significance, and observing a dose-response pattern. Lastly, there were associations between preeclampsia, preterm birth (<37 weeks) and low birthweight, however without reaching statistical significance.ConclusionOur results support the association between AMA and suffering repeated abortions. Likewise, being of AMA was associated with a greater risk of suffering from gestational diabetes, especially among primiparous women, as well as being associated with both instrumental deliveries and cesareans among both primiparous and multiparous women.

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Is primiparity a risk factor for advanced maternal age pregnancies?

Abstract: Primiparity is associated with increased pregnancy and foetal complications in advanced age pregnancies. However, the use of ART in this age group does not seem to be an additional risk factor.

Cited by 15 publications

References 25 publications

The effect of parity on obstetric and perinatal outcomes in pregnancies at the age of 40 and above: a retrospective study

The effect of parity on obstetric and perinatal outcomes in pregnancies at the age of 40 and above: a retrospective study

Evaluation of Pregnancy Outcomes at Advanced Maternal Age

Association between advanced maternal age and maternal and neonatal morbidity: A cross-sectional study on a Spanish population

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