2018
DOI: 10.1590/1678-5150-pvb-5490
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Iron supplementation for lambs experimentally infected by Haemonchus contortus: response to anemia and iron store in the bone marrow

Abstract: To evaluate the effect of supplementation of iron dextran on blood variables and iron metabolism in lambs experimentally infected by Haemonchus contortus, four experimental groups were used: uninfected and non-supplemented animals (GI); infected animals supplemented with iron (GII); uninfected animals supplemented with iron (GIII); and infected non-supplemented animals (GIV). Groups II and IV received 10,000 larvae (L3) of Haemonchus contortus, and groups II and III received three doses of iron dextran (20mg/k… Show more

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Cited by 9 publications
(5 citation statements)
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“…The significantly lower serum Zn and Fe levels of the infected lambs relative to the control suggest a disturbance in their metabolism caused by H. contortus . Both mixtures had high iron contents, so differences between unsupplemented infected lambs and infected lambs supplemented with a herbal mixture could influence the serum Fe status during treatment [58]. Some medicinal herbs from central Europe containing essential microelements have been reported to possess antioxidant capacity which is correlated with the content of total phenolic compounds [59].…”
Section: Discussionmentioning
confidence: 99%
“…The significantly lower serum Zn and Fe levels of the infected lambs relative to the control suggest a disturbance in their metabolism caused by H. contortus . Both mixtures had high iron contents, so differences between unsupplemented infected lambs and infected lambs supplemented with a herbal mixture could influence the serum Fe status during treatment [58]. Some medicinal herbs from central Europe containing essential microelements have been reported to possess antioxidant capacity which is correlated with the content of total phenolic compounds [59].…”
Section: Discussionmentioning
confidence: 99%
“…An increase in red blood cells had been previously reported in iron supplemented lambs (Casanova et al, 2018). This probably occurs since iron is an important component of nonenzymatic metalloproteins such as hemoglobin, ferredoxin and ferritin.…”
Section: Discussionmentioning
confidence: 71%
“…These consist of vitamin and mineral supplements which improve coagulation and stimulate erythropoiesis. This has a positive impact on blood cell counts, and on the sheep's energetic recovery (MOTTIN et al, 2019;CASANOVA et al, 2018).…”
Section: Introductionmentioning
confidence: 99%
“…Two of the hemograms performed showed microcytic erythrocytes, a characteristic alteration of iron deficiency. Lambs infected with H. contortus and supplemented with iron had less severe anemia than those not supplemented (Casanova et al 2018). This data may indicate that the association of supplements containing iron, minerals, amino acids, and vitamins is interesting with respect to increasing the speed of recovery of sick cattle.…”
Section: Discussionmentioning
confidence: 89%