Iridoids and other constituents from Cyperus rotundus L. rhizomes

Mohamed, Gamal A.

doi:10.1016/j.bfopcu.2015.01.001

Cited by 19 publications

(20 citation statements)

References 25 publications

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“…[ 8 ] It is a multivalent herb reported for its pharmacological properties such as an analgesic, antibacterial, antidiabetic, antidiarrheal, anti-inflammatory, antioxidant, antipruritic, antisaturative, appetizer, diaphoretic, digestant, lactodepurant, thirst relieving, and tranquilizing effect. [ 9 10 11 12 13 ] The phytochemical studies of C. rotundus L. led to the isolation of sesquiterpenes,[ 11 14 ] flavonoids,[ 15 16 17 ] phenylpropanoids,[ 18 19 ] phenolic acids,[ 18 20 ] alkaloids,[ 21 ] and saponins. [ 22 ] Investigations on C. rotundus L. rhizome (CRR) extract reported the presence of methyl 3,4-dihydroxybenzoate, ipolamiide, 6-β-hydroxyipolamiide, and rutin and also stated the uses of ethyl acetate fraction coupled with methanolic fraction in treatment of CCl 4 -induced hepatic injury in rats.…”

Section: Introductionmentioning

confidence: 99%

“…[ 22 ] Investigations on C. rotundus L. rhizome (CRR) extract reported the presence of methyl 3,4-dihydroxybenzoate, ipolamiide, 6-β-hydroxyipolamiide, and rutin and also stated the uses of ethyl acetate fraction coupled with methanolic fraction in treatment of CCl 4 -induced hepatic injury in rats. [ 13 ] Lydia J and Sudarsanam (2014) identified 15-Hydroxy-4-oxo-10-pentadecynoic acid lactone from C. rotundus L.[ 12 ] Recently, rotunduside, a phenolic compound from methanol extract of CRR, was isolated and its potential antidepressant activity with murine models was demonstrated. [ 23 ]…”

Section: Introductionmentioning

confidence: 99%

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In vitro antioxidant potentials of Cyperus rotundus L. rhizome extracts and their phytochemical analysis

Kamala

Middha²,

Gopinath³

et al. 2018

Phcog Mag

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Background:Cyperus rotundus L. (family Cyperaceae), native to India, is a multivalent medicinal plant widely used in conventional medicine. The research reports on bioactive components from C. rotundus L. are scanty.Objective:The objective of the study was to optimize the best solvent system and bioprospect the possible phytochemicals in C. rotundus L. rhizome (CRR).Materials and Methods:The phytochemicals were extracted from the rhizomes of C. rotundus L. by successive Soxhlet technique with solvents of increasing polarity. The resultant extracts were analyzed for their total flavonoid content (TFC), total phenolic content (TPC), total proanthocyanidin content (TPAC), in vitro antioxidant potential, and inhibition of lipid peroxidation. The 70% acetone extract of CRR was analyzed using gas chromatography–mass spectrometry (GC-MS) for probable phytochemicals.Results and Discussion:The TPC, TFC, and TPAC estimates ranged from 0.036 ± 0.002 to 118.924 ± 5.946 μg/mg extract, 7.196 ± 0.359 to 200.654 ± 10.032 μg/mg extract, and 13.115 ± 0.656 to 45.901 ± 2.295 μg/mg extract, respectively. The quantities of TPC, TFC, and TPAC were found to be the highest in 70% acetone extract. The 70% acetone and 70% methanol extracts revealed best radical scavenging effect. GC-MS analysis of CRR extract revealed the presence of a novel compound 1 (2)-acetyl-3 (5)-styryl-5 (3)-methylthiopyrazole.Conclusion:The study indicated that 70% acetone and 70% methanol extracts of CRRs can be a potential source of antioxidants.SUMMARY The studies suggest 70% methanol and acetone as the suitable solvents for the extraction of phytochemicalsNovel compound 1(2)-Acetyl-3(5)-styryl-5(3)-methylthiopyrazole was detected in 70% acetone extract. Abbreviations used: ACRE: Acetone C. rotundus L. rhizome extract; AlCl3: Aluminum chloride; AQRE: Aqueous C. rotundus L. rhizome extract; CE: Catechin Equivalent; CHRE: Chloroform C. rotundus L. rhizome extract; CRR: C. rotundus L. rhizome; DPPH: 2,2 diphenyl-1-picrylhydrazyl; ETRE: Ethanolic C. rotundus L. rhizome extract; EARE: Ethyl acetate C. rotundus L. rhizome extract; FRP: Ferric reducing power; GAE: Gallic acid equivalent; GC-MS: Gas chromatography-mass spectrometry; HERE: Hexane C. rotundus L. rhizome extract; MERE: Methanolic C. rotundus L. rhizome extract; PERE: Petroleum ether C. rotundus L. rhizome extract; QE: Quercetin equivalent; RNS: Reactive nitrogen species; ROS: Reactive oxygen species; TFC: Total flavonoid content; TPC: Total phenolic content; TPAC: Total proanthocyanidin content.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

In vitro antioxidant potentials of Cyperus rotundus L. rhizome extracts and their phytochemical analysis

Kamala

Middha²,

Gopinath³

et al. 2018

Phcog Mag

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“…Its mass spectrum displayed a molecular ion peak at m/z 464 corresponding to a molecular formula of an aliphatic ketone, C 32 13 C NMR spectrum ruled out the unsaturated nature of the molecule. On the basis of foregoing spectral data analysis, the structure of 2 has been elucidated as n-dotriacontan-15-one, a new aliphatic ketone (Fig.…”

Section: Resultsmentioning

confidence: 99%

Chemical Constituents from the Rhizomes of Cyperus Rotundus L.

Sultana¹,

M²,

Mir³

2017

TOPSJ

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Background:Cyperus rotundus L. (Cyperaceae), is a perennial sedge distributed throughout India and other parts of the world. Its tubers are used as an appetizer, febrifuge and to treat bleeding, blisters, boils, cough, diarrhea, inflammation, lacteal disorders, rheumatoid arthritis, stomach ailments, skin rashes, thirst, vomiting, worm infestation and wounds. Objective:Our study was planned to isolate chemical constituents from the rhizomes of C. rotundus and to characterized their structures. Method:The air-dried rhizome powder was exhaustively extracted with methanol in a Soxhlet apparatus. The concentrated methanol extract was adsorbed on silica gel (60-120 mesh) for the preparation of a slurry. The dried slurry was chromatographed over silica gel column packed in petroleum ether. The column was eluted with petroleum ether, chloroform and methanol, successively, in order of increasing polarity to isolate the compounds. Results:Phytochemical investigation of the tubers led to isolate a sesquiterpenone characterized as 12-methyl cyprot-3-en-2-one-13-oic acid (1), two aliphatic ketone viz. n-dotriacontan-15-one (2) and n-tetracontan-7-one (8), fatty esters n-pentadecanyl octadec-9, 12-dienoate (n-pentadecanyl linoleate, 3), n-hexadecanyl linoleate (4), n-hexadecanyl oleate (5) and n-pentacos-13ʹ-enyl octadec-9-enoate (n-pentacos-13ʹ-enyl oleate, 9), two steroidal esters stigmast-5,22-dien-3β -olyl n-dodecanoate (stigmasterol laurate, 6) and stigmast-5, 22-dien-3β-olyl n-tetradecanoate (stigmasterol myristate, 7), β-sitosterol-3β-O-glucoside (10) and a triterpenic glycosidic ester lup-12, 20 (29)-dien-3β-ol-3-α-L-arabinopyranosyl-2'-oleate (lupenyl 3β-O-arabinpyranosyl 2′-oleate, 11). The structures of these compounds were established by spectral data analysis and chemical reactions. Conclusion:A sesquiterpene identified as cyprot-3-en-2-one-14-oic acid, two aliphatic ketones, fatty esters, two steroidal esters, β-sitosterol-3β-O-glucoside and lupenyl 3β-O-arabinpyranosyl 2′-oleate were isolated for the first time from the rhizomes.

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“…The smell of teki grass rhizome extract is originated from teki grass and fruits as the flavor additional used ( Figure 3). The distinct smell of teki is originated from the essential oil which is a volatile component giving the peculiar smell of teki (Mohamed, 2015). Such compound are for example cineole, cyperene, cyperenone, cyperol, cyprerotundone, limonene (Zhou and Yin, 2012).…”

Section: The Organoleptic Test Of the Functional Beverage Of The Extrmentioning

confidence: 99%

“…Teki grass (Cyperus rotundus L.) is a kind of grass growing wildly, and it is easy to find. This particular plant is included in Cyperaceae family more acknowledged as a "World's Worst Weed" or destruction plant (Mohamed, 2015). As a herb plant, teki grass can potentially be used as traditional medicine ingredient, and it does not give side effect for the health so it is safe to consume.…”

Section: Introductionmentioning

confidence: 99%

Functional Drinks from a Rhizome of Nut Grass (Cyperus rotundus L.) with Mixed Fruits

Devi¹,

Soekopitojo²,

Merawati³

2020

Proceedings of the 2nd International Conference on Social, Applied Science, and Technology in Home Economics (ICONHOMECS 2019)

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This research aims to get the technology of production process of the functional beverage of teki extract to obtain the formula of the functional beverage made of teki grass rhizome extract preferred by girls teenagers to cure the dysmenorrhoea problem. Such functional beverage is made of the extract of teki grass rhizome and the extract of any fruits such as pineapple, strawberry, and soursop added sugar and water. The production of teki extract is through the stages of sorting, washing, blanching, demolition, blending, heating and filtering. The chemical quality (Ca, Mg and Femineral) and the organoleptic characteristics (hedonic and hedonic quality) of teki extract were analyzed, and the experimentalmouse was pre-clinical tested to know its effect on the heart function by using SGPT and SGOT analysis. The research results show that the formula of teki extract with the rhizome of teki grass and the extract of pineapple (b/b) is recommended based on the hedonic characteristics andhedonic quality of taste, smell and the mineral contain such as Ca (2.27 ppm), Mg (46,94 ppm) and Fe (1,09 ppm).The teki extract has sweet-sour taste and theratherstrongdistinctive smell of teki.

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Iridoids and other constituents from Cyperus rotundus L. rhizomes

Cited by 19 publications

References 25 publications

In vitro antioxidant potentials of Cyperus rotundus L. rhizome extracts and their phytochemical analysis

In vitro antioxidant potentials of Cyperus rotundus L. rhizome extracts and their phytochemical analysis

Chemical Constituents from the Rhizomes of Cyperus Rotundus L.

Functional Drinks from a Rhizome of Nut Grass (Cyperus rotundus L.) with Mixed Fruits

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