IORT Novac7: A New Linear Accelerator for Electron Beam Therapy

Fantini, M.; Santoni, F.; Soriani, A.; Creton, G.; Benassi, Marcello; Begnozzi, L.

doi:10.1159/000061145

Cited by 10 publications

(5 citation statements)

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“…However, for 3 MeV and 5 MeV electron beams the dose-per-pulse values measured at z ref were almost independent of the applicator diameter (5.1 and 12 mGy/pulse for 3 MeV and 5 MeV, respectively). This is also in good agreement with results given in the literature [15]. …”

Section: Comparison Of Different Methodssupporting

confidence: 93%

“…This trend was not observed for 3 MeV and 5 MeV electrons. However, Fantini et al [15] have reported analogous findings. The constancy of the dose-per-pulse value with decreasing applicator diameter may be due to the absorption of low-energy scattered electrons before they reach the z ref .…”

Section: Discussionmentioning

confidence: 81%

“…The NOVAC7 (SIT, Vicenza/Italy) is a dedicated mobile electron linear accelerator for IORT and has been used in several European IORT facilities since 1998 [15]. It has many advantages compared to other non-dedicated IORT treatment systems: high surface dose (>80%), low total bremsstrahlung photon dose (<0.3%), small in size and light weight with different electron energies (3, 5, 7 and 9 MeV) and different cylindrical applicator sizes with diameters from 30 mm to 100 mm [3].…”

Section: Novac7 Iort Systemmentioning

confidence: 99%

See 2 more Smart Citations

Determination of the ion recombination correction factor for intraoperative electron beams

Besheli

Simiantonakis

Zink

et al. 2016

Zeitschrift für Medizinische Physik

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Section: Comparison Of Different Methodssupporting

confidence: 93%

Section: Discussionmentioning

confidence: 81%

Section: Novac7 Iort Systemmentioning

confidence: 99%

See 1 more Smart Citation

Determination of the ion recombination correction factor for intraoperative electron beams

Besheli

Simiantonakis

Zink

et al. 2016

Zeitschrift für Medizinische Physik

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“…In principle, IORT can be applied using electrons of a linear accelerator situated in the operating theatre or nearby [ 4 ] or of special electron accelerators like Novac7™ [ 5 ] or Mobetron™ [ 6 ]. Another possibility is the application of brachytherapy using a Ir-192 source guided by needles or plastic tubes within silicone flaps which are very useful to maintain the irradiation geometry [ 7 ].…”

Section: Introductionmentioning

confidence: 99%

Intraoperative radiotherapy (IORT) combined with external beam radiotherapy (EBRT) for soft-tissue sarcomas – a retrospective evaluation of the Homburg experience in the years 1995–2007

et al. 2009

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Abstract

Purpose

To retrospectively evaluate the results after a regimen of surgery, IORT (intraoperative radiotherapy), and EBRT (external beam radiotherapy) for soft-tissue sarcomas

Methods

38 consecutive patients underwent IORT for soft-tissue sarcoma; 29 were treated for primary tumours, 9 for recurrences. There were 14 cases with liposarcomas, 8 with leiomyosarcomas, 7 with malignant fibrous histiocytomas. 27/38 tumours were located in the extremities, the remaining ones in the retroperitoneum or the chest. Radical resection was attempted in all patients; a R0-resection was achieved in 15/38 patients, R1 in 12/38 pats and R2 in 4/38 pats. IORT was performed using a J-125 source and a HDR (high dose rate) afterloading machine after suturing silicone flaps to the tumour bed. The total dose applied ranged from 8–15 Gy/0.5 cm tissue depth measured from the flap surface. After wound healing external beam radiotherapy (EBRT) was applied in 31/38 patients with total doses of 23–56 Gy dependent on resection status and wound situation. The mean duration of follow-up was 2.3 years.

Results

A local recurrence was found in 10/36 patients, lymph node metastases in 2/35, and distant metastases in 6/35 patients. The actuarial local control rate was 63%/5 years. The overall survival rate was 57%/5 years. There was no statistically significant difference between the results after treatment for primaries or for recurrences. Late toxicity to the skin was found in 13/31 patients, wound healing problems in 5/31 patients. A neuropathy was never seen.

Conclusion

The combination of surgery, IORT, and EBRT yields favourable local control and survival data which are well within the range of the results reported in the literature. The complication rates, however, are considerable although the complications are not severe, they should be taken into account when therapy decisions are made.

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“…Akcelerator Novac składa się z konsoli sterującej oraz ruchomej jednostki terapeutycznej zawierającej strukturę przyspieszającą elektrony, połączoną ze źródłem mikrofal i modulatorem za pomocą elastycznego falowodu. Głowica akceleratora charakteryzuje się sześcioma stopniami swobody, a cały system waży mniej niż 650 kg [11,12] Akceleratory stosowane do IORT są w stanie wygenerować wiązkę promieniowania elektronowego najczęściej o energiach w zakresie od 4 MeV do 12 MeV, dla których przykładowe rozkłady głębokościowe przedstawiono na rysunku 2. Wybór odpowiedniej energii umożliwia dopasowanie głębokości penetracji promieniowania do grubości napromienianej tkanki, tak aby izodozą terapeutyczną objąć wyznaczoną objętość.…”

Section: Aparatura Do Ioertunclassified

Radioterapia śródoperacyjna z wykorzystaniem elektronów

Graczyk

Kruszyna-Mochalska

Kijeska

2022

LOS

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Taktyki leczenia, które łączą ze sobą oszczędzającą operację chirurgiczną z radioterapią stały się standardem w leczeniu wczesnych nowotworów. Jednym z przykładów skojarzonego leczenia jest wykonanie radioterapii śródoperacyjnej, którą przeprowadza się w trakcie zabiegu chirurgicznego, gdy pacjent nadal znajduje się pod anestezją w sterylnej sali operacyjnej. Celem pracy jest omówienie techniki radioterapii śródoperacyjnej wykorzystującej wiązkę elektronów (IOERT) generowaną przez mobilne akceleratory. Metoda IOERT znajduje swoje zastosowanie w leczeniu nowotworów takich lokalizacji jak: pierś, prostata, trzustka, okrężnica i odbytnica. Na podstawie doniesień literaturowych omówione zostało: przebieg procedury, najczęściej stosowane parametry fizyczne oraz wyzwania związane z kontrolą jakości i ochroną radiologiczną personelu.

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IORT Novac7: A New Linear Accelerator for Electron Beam Therapy

Cited by 10 publications

References 0 publications

Determination of the ion recombination correction factor for intraoperative electron beams

Determination of the ion recombination correction factor for intraoperative electron beams

Intraoperative radiotherapy (IORT) combined with external beam radiotherapy (EBRT) for soft-tissue sarcomas – a retrospective evaluation of the Homburg experience in the years 1995–2007

Radioterapia śródoperacyjna z wykorzystaniem elektronów

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