Investigations on Physico-Mechanical and Spectral Studies of Zn2+ Doped P2O5-Based Bioglass System

Abstract

ZnO incorporated phosphate based bioglasses with the composition xZnO–22Na2O–24CaO–(54-X)P2O5 (where X = 2, 4, 6, 8, 10 mol%) were developed by melt-quenching process. The physical, thermal and other structural properties of the glasses were studied in detail. By employing various characterization techniques such as X-ray powder diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), Scanning electron microscopy (SEM) in addition to the energy dispersion spectroscopy (EDS), and Raman spectroscopy, the structural properties were analyzed. Interestingly, physical, thermal and mechanical properties were enhanced with the increasing content of zinc oxide up to 8 mol%, due to the presence of more ionic nature of P–O–Zn bonds than P–O–P bonds in the glass network. The FTIR and Raman analysis revealed the evolution of the phosphate network with increasing zinc concentration and leads to progressive depolymerisation of the glass network. The obtained results from the physical and structural properties of these zinc added calcium phosphate glasses support their potential to use as bone implant applications.

Stimulated Full-Thickness Cutaneous Wound Healing with Bioactive Dressings of Zinc and Cobalt Ion-Doped Bioactive Glass-Coated Eggshell Membranes in a Diabetic Rabbit Model

“…47 C−O vibration produced a small band at 1465 cm −1 ; 4848 one H−O−H deformation mode is present at 1630 cm −1 ; and an engrossed water hump is present at 3445 cm −1 . 49 Because of the ZnO 4 structural component, the unique Zn−O band at 485 cm −1 was seen in Zn-BAG and binary doped BAG powders (Figure 3B), whereas Co−O doping in base BAG indicated a shift in the concentration of 780 cm −1 Si−O−Si symmetric stretch of nonbridging oxygen. In composites (Figure 3A), it is possible to identify the positions of both the unique bioactive glass functional bands and the amide bands (for the eggshell membrane).…”

“…FTIR of Figure B (base BAG) revealed a distinctive silicate system (because of the chief component being SiO 2 ) at various Si–O–Si stretching [for instance, 1030 cm –1 : asymmetric and 780 cm –1 : symmetric] and rocking (about 480 cm –1 ) while associating all configurations of BAG powders one H–O–H deformation mode is present at 1630 cm –1 ; and an engrossed water hump is present at 3445 cm –1 . Because of the ZnO 4 structural component, the unique Zn–O band at 485 cm –1 was seen in Zn-BAG and binary doped BAG powders (Figure B), whereas Co–O doping in base BAG indicated a shift in the concentration of 780 cm –1 Si–O–Si symmetric stretch of nonbridging oxygen.…”

Bioactive Glass—An Extensive Study of the Preparation and Coating Methods

“…Moreover, zinc [213] and copper [214] ions give antimicrobial properties to the bioactive glass coating [215]. Furthermore, by adding zinc, the chemical stability and mechanical properties of the bio-glass can be improved [216,217].…”

3D Printing Assisted Fabrication of Copper–Silver Mesoporous Bioactive Glass Nanoparticles Reinforced Sodium Alginate/Poly(vinyl alcohol) Based Composite Scaffolds: Designed for Skin Tissue Engineering

“…Some common examples of phosphate BGs and borate BGs are 47P 2 O 5 , 30.5CaO, x Na 2 O, y K 2 O (with varying concentrations of x and y ) . Mono-/di-/tri-/tetracalcium phosphates, α-/β-tricalcium phosphate, various transition metal ions (Ca 2+ , Na + , Zn 2+ ,Mg 2+ , Sr 2+ , and K + ) doped phosphate BGs and 45S5B5 (40SiO 2 , 24.5NaO, 24.5CaO, 6P 2 O 5 , 5B 2 O 3 ), 13–93B3 (54B 2 O 3 , 22CaO, 8K 2 O, 8MgO, 6Na 2 O, 2P 2 O 5 ), and 45S5B1 (46.1B 2 O 3 , 26.9CaO, 24.4Na 2 O, 2.6P 2 O 5 ), respectively. , Zhou et al compared 13-93B3 and 45S5 microfiber wound dressings for full-thickness skin defect in a rat model. Both materials exhibited dermal reconstruction potential; however, borate BG (13–93B3) demonstrated an accelerated healing rate as compared to phosphate BG (45S5).…”