Investigation of the bone metabolism in dogs with leishmaniasis

Abstract

The present study was aimed at determining bone metabolism related changes in dogs with visseral leishmaniasis such as vitamin D, calcium, phosphate and ALP levels as compared to healthy ones. A total of 40 serums of male dogs aged between 4 and 6 years that were sent to Adnan Menderes University, Faculty of Medicine, Parasitology Laboratory from Kuşadasy and Bodrum districts between the years 2012 and 2013, suspected with leishmaniasis, by the veterinary physicians in accordance with the cold chain rules and 20 of which were evaluated as leishmania seropositive and 20 as leishmania seronegative by the IFA test, were included in this study. There was no any statistically significant difference between the serum 25-OH-D 3 levels of Leishmania positive and negative dogs (p>0.05). There was a statistically significant difference between the serum ALP (p<0.05), and P levels were observed to be higher in the seropositive dogs than in the seronegative dogs, while Ca level was low (p<0.001).