Investigation of antioxidant status in children with acute otitis media and tonsillitis

Oxidative stress and enzymic–non-enzymic antioxidant responses in children with acute pneumonia

“…From the unchanged CAT levels, it can be speculated that CAT is not as effective as the GPx since the latter enzyme is much more active than the CAT in most antioxidant reactions. 29 Even though some investigators 24,25 and our present study revealed decreased SOD and GPx levels in pneumonia, our two previous studies 30,31 and those of Shukla et al 32 showed increased SOD, GPx and CAT levels in several infectious diseases such as meningitis, encephalitis, otitis media and tonsillitis. Similarly to Parks et al 33 and Aktan et al, 34 our present study showed that CAT levels remained unchanged in diseases such as experimental otitis media and pneumonia.…”

Oxidant and antioxidant levels in children with acute otitis media and tonsillitis: A comparative study

“…Furthermore, the decrease in b-carotene and retinol levels in AOM group was also more effective compared to AT even though these were not statistically important. In our previous study, when we measured the enzymatic antioxidant system (SOD, GPx and CAT) in the same diseases like AOM and AT, it was very interesting to find that SOD and GPx activities were increased more prominently in AT group than that of AOM [34]. Under the light of these findings, the response intensity against the oxidative challenge in the body depends on the specific tissue itself.…”

Oxidants and antioxidants in tonsillar and adenoidal tissue in chronic adenotonsillitis and adenotonsillar hypertrophy in children

“…Cemek et al [13] explain this contrary with the onset of diseases. They argue that disease starts spontaneously in humans whereas it is induced experimentally in animals and because of this difference local defense might be adapting to the developing oxidative stress in humans better than of animals.…”