Introduction to Active Smart Materials for Biomedical Applications

Greco, Francesco; Mattoli, Virgilio

doi:10.1007/978-3-642-28044-3_1

Cited by 13 publications

(10 citation statements)

References 104 publications

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“…Smart biomaterials in association with tissue engineering modify a number of functional as well as structural properties and impose external stimulus on their surrounding conditions. 26 The external stimulus is physical (temperature, light, electric, or magnetic fields), chemical (pH), or mechanical stimuli (stress, strain). The suitable category of the piezoelectric materials steps generate an electrical signal against mechanical deformation and vice versa.…”

Section: Introductionmentioning

confidence: 99%

Smart Piezoelectric Nanohybrid of Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) and Barium Titanate for Stimulated Cartilage Regeneration

Jacob

Choppadandi

et al. 2019

ACS Appl. Bio Mater.

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Piezoelectric materials strive to articulate smart materials and transduce electric fields by applying mechanical pressure and vice versa. This study demarcates augmented cartilage regeneration from the praxis of the smart material intervention that denotes the method of the utilized piezoelectric mechanism. The smart piezoelectric nanohybrid is developed from poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) and barium titanate (BaTiO 3 ). Further, the electrospinning technique is adopted for the scaffolding to mimic the structure of natural cartilage. The scaffold with 20% BaTiO 3 shows enhanced mechanical properties and a piezoelectric coefficient (1.4 pC/ N) similar to native tissue. Interestingly, the corona poled (electrically polarized) scaffolds demonstrated better cellular activity than unpoled. Human mesenchymal stem-cell-derived chondrocytes are utilized for in vitro studies. The polarized scaffolds highly promote the cell attachment, proliferation, and collagen II gene expression against control (pure PHBV) and unpolarised scaffolds; the effect was quite dominant even in high-piezoelectric-coefficient scaffolds. Therefore, the electric-field-originated scaffolds show the potential effect on cartilage regeneration without the addition of any stimulating molecules.

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Section: Introductionmentioning

confidence: 99%

Smart Piezoelectric Nanohybrid of Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) and Barium Titanate for Stimulated Cartilage Regeneration

Jacob

Choppadandi

et al. 2019

ACS Appl. Bio Mater.

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“…In light of material advances, downscaling of manufacturing and computer aided design, many new interdisciplinary applications appear that make use of a nature-inspired palette of solutions for engineering problems. In engineering the interest for morphing is growing in many fields such as aerospace industry [2,13], building engineering [14], micro-scale actuation [15], wind turbines [16,17], automotive industry [18] or medicine [19].…”

Section: Introductionmentioning

confidence: 99%

Kinematic amplification strategies in plants and engineering

Charpentier¹,

Hannequart²,

Adriaenssens³

et al. 2017

Smart Mater. Struct.

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While plants are primarily sessile at the organismal level, they do exhibit a vast array of movements at the organ or sub-organ level. These movements can occur for reasons as diverse as seed dispersal, nutrition, protection or pollination. Their advanced mechanisms generate a myriad of movement typologies, many of which are not fully understood. In recent years, there has been a renewal of interest in understanding the mechanical behavior of plants from an engineering perspective, with an interest in developing novel applications by up-sizing these mechanisms from the micro-to the macro-scale. This literature review identifies the main strategies used by plants to create and amplify movements and anatomize the most recent mechanical understanding of compliant engineering mechanics. The paper ultimately demonstrates that plant movements, rooted in compliance and multi-functionality, can effectively inspire better kinematic/adaptive structures and materials. In plants, the actuators and the deployment structures are fused into a single system. The understanding of those natural movements therefore starts with an exploration of mechanisms at the origins of movements. Plant movements, whether slow or fast, active or passive, reversible or irreversible, are presented and detailed for their mechanical significance. With a focus on displacement amplification, the most recent promising strategies for actuation and adaptive systems are examined with respect to the mechanical principles of shape morphing plant tissues.

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“…Shape memory alloys (SMA) and polymers are the widely known examples of smart materials that can be useful in changing surface properties and for self-healing, self-restoring effects (Machado and Savi 2003;Greco and Mattoli 2012). NiTi-based shape memory alloys often used in commercial orthopedic applications because of good mechanical features (Feninat et al 2002;Tarniţă et al 2009).…”

Section: New Approaches In Orthopedic Implants Smart Implantsmentioning

confidence: 97%

Implant Strategies in Orthopedics

Koksal¹

2014

Sports Injuries

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Orthopedic implant technology is carrying on advancing each day and offers different treatments with different materials and technologies. In this chapter, the uses of implants in orthopedics and new approaches like smart implants or surface modifications and stem cell applications are mentioned. Besides, regulations for orthopedic implants and the future of implant sector are explained from the perspective of new and emerging technologies.

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Introduction to Active Smart Materials for Biomedical Applications

Cited by 13 publications

References 104 publications

Smart Piezoelectric Nanohybrid of Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) and Barium Titanate for Stimulated Cartilage Regeneration

Smart Piezoelectric Nanohybrid of Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) and Barium Titanate for Stimulated Cartilage Regeneration

Kinematic amplification strategies in plants and engineering

Implant Strategies in Orthopedics

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