Intravascular large B-cell lymphoma presenting as panniculitis

Maiolo, Corinne; Ibbetson, S. Jan; Sidhu, Shireen; Kearney, Daniel

doi:10.1016/j.jdcr.2017.06.032

Cited by 3 publications

(4 citation statements)

References 8 publications

(17 reference statements)

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“…[ 3 ] Maiolo et al . [ 4 ] reported a case of intravascular large B-cell lymphoma in a 77-year-old Iranian woman who presented with a 3-month history of painful abdominal and inframammary subcutaneous nodules. Phoon et al .…”

Section: Discussionmentioning

confidence: 99%

A case of intravascular lymphoma masquerading as calciphylaxis in a patient on haemodialysis

Banerjee

Majumdar

2022

Indian J Nephrol

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Intravascular large B-cell lymphoma (IVLBCL) is a rare lymphoma entity with intravascular proliferation of clonal lymphocytes restricted to the lumen of small- and medium-sized blood vessels. In this case report, we describe a 70-year-old lady on maintenance hemodialysis who presented with altered sensorium and painful lesions over her inner thigh. While preliminary investigations were favoring calciphylaxis, it was the skin biopsy that showed vasculopathic lymphoid infiltrate with focal panniculitis, consistent with intravascular lymphoma. Although overall survival is poor, prompt use of intensive therapies have shown to improve the outcome.

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Section: Discussionmentioning

confidence: 99%

A case of intravascular lymphoma masquerading as calciphylaxis in a patient on haemodialysis

Banerjee

Majumdar

2022

Indian J Nephrol

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“…Częstość występowania objawów skórnych jest szacowana na 17-39% [6,13]. Można do nich zaliczyć: teleangiektazje [14,15], rumień stwardniały, bolesne guzki, zmiany obrączkowate, osutkę plamisto-grudkową [16], zapalenie tkanki podskórnej [16,17], obrzęk limfatyczny kończyn dolnych [14], zmiany typu skórki pomarańczy [18], plamicę, owrzodzenia [16], naczyniaki gwiaździste. Niekiedy zmiany mogą przypominać zespół Sweeta, mięsak Kaposiego lub twardzinę ograniczoną [19].…”

Section: Wprowadzenieunclassified

“…The incidence of skin symptoms is estimated at 17-39% [6,13]. These include telangiectasia [14,15], erythema induratum, painful nodules, annular lesions, maculopapular eruptions [16], panniculitis [16,17], lymphedema of lower limbs [14], orange peel skin [18], purpura, petechiae, skin ulcers [16], senile angioma; sometimes skin lesions can mimic: Sweet syndrome, Kaposi sarcoma, morphea [19]. The cutaneous variant can be associated with better prognosis [5,20], but some authors deny its existence [13].…”

Section: Wprowadzeniementioning

confidence: 99%

Intravascular large B-cell lymphoma

Odziomek¹,

Jarliński²,

Rebizak³

et al. 2021

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Introduction. Intravascular large B-cell lymphoma is a rare type of lymphoma. The clinical presentation is dominated by skin lesions and central nervous system involvement. Objective. This article presents the case of a cutaneous manifestations of intravascular large B-cell lymphoma. Case report. A 64-year-old female was admitted to the dermatology department with widespread cutaneous telangiectasia. Seven months prior to the admission microcytic anaemia was diagnosed. The diagnosis of intravascular large B-cell lymphoma was based on histopathology. The patient died 3 days after introduction of chemotherapy. Conclusions. Intravascular large B-cell lymphoma presents with a nonspecific clinical presentation that may mimic many dermatoses, requiring complex differential diagnosis. streszczenie Wprowadzenie. Wewnątrznaczyniowy chłoniak z dużych komórek B jest rzadkim typem chłoniaka. W obrazie klinicznym dominują zaburzenia neurologiczne i objawy skórne. Cel pracy. Przedstawienie przypadku pacjentki z wewnątrznaczyniowym chłoniakiem z zajęciem skóry. Opis przypadku. Kobieta 64-letnia została skierowana na oddział dermatologiczny z powodu rozległych teleangiektazji. Siedem miesięcy wcześniej stwierdzono u niej niedokrwistość mikrocytarną. Diagnozę postawiono na podstawie wyniku badania histopatologicznego skóry. Pacjentka zmarła 3 dni po rozpoczęciu chemioterapii. Wnioski. Ze względu na stosunkowo częste występowanie objawów skórnych w przebiegu wewnątrznaczyniowego chłoniaka z dużych komórek B oraz nieswoisty obraz kliniczny przypominający wiele dermatoz wskazana jest złożona diagnostyka różnicowa.

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confidence: 99%

Intravascular large B‐cell lymphoma mimicking erythema nodosum: A case report and review of published works

Itami

Miyagaki

Miyano

et al. 2021

The Journal of Dermatology

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| e185LETTER TO THE EDITOR clinical courses have been reported in the English-language literature. [1][2][3][4][5] The clinical features of six cases including our case are summarized in Table S1. The average age at first visit was 60.3 years. Four cases had lesions limited to the lower legs and two cases had lesions distributed in the body area. The diagnosis of IVLBCL was made immediately after the first visit in two cases with long-lasting fever, whereas the other four cases were diagnosed as other diseases. Resistance to standard therapies including oral prednisolone and antibiotics or appearance of neurological or blood abnormalities led to the diagnosis of IVLBCL in those cases. All patients were treated with combination chemotherapies and the long-term prognosis was described in two cases. One patient died due to respiratory failure at 9 months after diagnosis and another patient was alive with complete remission at 30 months. When caring for patients with panniculitis, it is important to consider the possibility of IVLBCL. Systemic symptoms such as long-lasting fever and neurological abnormalities, blood abnormalities including elevation of lymphoma markers, or poor response to conventional therapies can indicate the possibility of malignant diseases.

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Intravascular large B-cell lymphoma presenting as panniculitis

Cited by 3 publications

References 8 publications

A case of intravascular lymphoma masquerading as calciphylaxis in a patient on haemodialysis

A case of intravascular lymphoma masquerading as calciphylaxis in a patient on haemodialysis

Intravascular large B-cell lymphoma

Intravascular large B‐cell lymphoma mimicking erythema nodosum: A case report and review of published works

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