A case of intravascular lymphoma masquerading as calciphylaxis in a patient on haemodialysis

Abstract

Intravascular large B-cell lymphoma (IVLBCL) is a rare lymphoma entity with intravascular proliferation of clonal lymphocytes restricted to the lumen of small- and medium-sized blood vessels. In this case report, we describe a 70-year-old lady on maintenance hemodialysis who presented with altered sensorium and painful lesions over her inner thigh. While preliminary investigations were favoring calciphylaxis, it was the skin biopsy that showed vasculopathic lymphoid infiltrate with focal panniculitis, consistent with intravascular lymphoma. Although overall survival is poor, prompt use of intensive therapies have shown to improve the outcome.