Intrasellar schwannoma: A rare case of pituitary incidentaloma

Carceller, Diana Boj; Gamboa, Ramón Albero; Sanz, Guayente Verdes; Arregui, Sandra Vicente; Alegret, Ramiro Álvarez

doi:10.1016/j.endoen.2011.10.006

Cited by 4 publications

(11 citation statements)

References 8 publications

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“…According to the reported cases [Table 1], intrasellar schwannomas pick young to elder age groups and are more common in elderly individuals in an average of 49.5 years (range: 19-79 years). [1,[3][4][5][6][7][8][9][11][12][13][14][15][16]19,[21][22][23][24][25]27,29,30,32,33,35] ey have a good prognosis and affect males to females equally (20:19).…”

Section: Resultsmentioning

confidence: 99%

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Ectopic schwannoma of the sellar region in a 1-year-old child: A case report and review of literature

Sadiqo¹,

Abdulsada

Ismail

et al. 2022

Surgical Neurology International

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Background: Schwannomas are cranial and spinal nerves’ sheath tumors accounting for up to 8% of all intracranial neoplasms. Although typical intracranial schwannomas originate from Schwann cells surrounding cranial nerves, ectopic schwannomas are not associated with a known cranial nerve or have an unknown origin. The location of schwannomas may impose clinical challenges. Sellar region schwannomas are rare whether it is ectopic or not. Herein, we report a pediatric case of a 1-year-old female with ectopic, intra-supra sellar with a literature review. We report the first case of juvenile ectopic schwannoma in the sellar region. Methods: A PubMed Medline database search was performed by the following combined formula of medical subject headings (MESH) terms and keywords: ((sella turcica [MeSH Terms]) OR (sella*[Title/Abstract]) OR (ectopic [Title/Abstract]) AND ((neurilemmoma [MeSH Terms]) OR (schwannoma [Title/Abstract]) OR (neuroma [Title/Abstract]) OR (neurinoma [Title/Abstract])). Results: Total results of 206 articles were obtained. In exclusion of intraparenchymal and intraventricular schwannomas, only 34 articles remained. Thirty-nine cases were included in 34 articles. According to the reported cases, intrasellar schwannomas are more common in elderly individuals in an average of 49.5 years (range: 19– 79 years). They have a good prognosis and affect males to females equally (20:19). Conclusion: Ectopic schwannoma sited in the sellar region is rare. It is the first case to be reported in the pediatric age group with a literature review. This lesion should be highlighted and included in the differential diagnosis of sellar mass.

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Section: Resultsmentioning

confidence: 99%

“…Although schwannomas are benign tumors of children and adults, sellar schwannomas have not been reported in [16] 2010 M 38 Acromegalia Elevated growth hormone TSA Normalized pituitary function Boj-carcellar et al [3] 2012 F 56 HA Normal TSA+TCA Hypopituitarism…”

Section: Outcomementioning

confidence: 99%

Ectopic schwannoma of the sellar region in a 1-year-old child: A case report and review of literature

Sadiqo¹,

Abdulsada

Ismail

et al. 2022

Surgical Neurology International

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“…The remaining neoplasms are benign tumors (craniopharyntgiomas and meningiomas), malignant tumors (primary germ cell tumors, chordomas, lymphomas, and pituitary adenocarcinomas, or metastatic disease mainly from breast and lung cancer), and other uncommon conditions (cysts, abscesses, arteriovenous fistulas, lymphocytic hypophysitis) [3]. As mentioned before, schwannoma accounts for up to 8% of primary brain tumors [4], and is usually associated with the cranial nerves and shows a special predilection for the vestibular portion of the 8th cranial nerve at the cerebellopontine angle, while intrasellar localization is exceptional.…”

Section: Discussionmentioning

confidence: 99%

Hard calcified intrasellar schwannoma mimicking pituitary adenoma: A case report and review of the literature

Sharifi¹,

Bakhtevari²,

Alghasi³

et al. 2015

Clinical Neurology and Neurosurgery

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“…Sin em-bargo, otras lesiones no adenomatosas pueden estar presentes, dentro de ellas los schwannomas, con comportamiento similar al de los adenomas no funcionales (ANF) 3,4 . Representan un 8 a 10% de los tumores primarios intracraneales, y su localización selar es muy infrecuente 5,6 . Al momento del diagnóstico suelen ser grandes y con extensión supra-y paraselar, dando lugar a síntomas compresivos.…”

Section: Introductionunclassified

“…Al momento del diagnóstico suelen ser grandes y con extensión supra-y paraselar, dando lugar a síntomas compresivos. El diagnóstico diferencial requiere, en muchos casos, inmunohistoquímica [6][7][8] . Se presenta un caso de un schwannoma selar con sus características clínicas, imagenológicas y probables complicaciones quirúrgicas.…”

Section: Introductionunclassified

Schwannoma como diagnóstico diferencial de masas selares: reporte de un caso y revisión de la literatura

Loto¹

2020

RFEM

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Los schwannomas representan un 8% de los tumores intracraneales; los intraselares son extremadamente infrecuentes. Se presenta un caso interpretado inicialmente como macroadenoma no funcionante. Paciente masculino referido por hallazgo incidental de tumor selar. Sin signos de disfunción pituitaria ni alteraciones visuales. La resonancia magnética nuclear evidencia lesión heterogénea de 15 mm, que refuerza con gadolinio, en contacto con el quiasma óptico. El campo visual, al igual que la función pituitaria, resultan normales en la evaluación basal. Con diagnóstico presuntivo de macroadenoma no funcionante, se decide intervención por vía transesfenoidal, lográndose la resección completa de la masa. Luego de la cirugía presenta múltiples complicaciones. La anatomía patológica revela schwannoma, con inmunohistoquímica positiva para proteína S100. Los schwannomas, si bien infrecuentes, deben ser considerados dentro de los diagnósticos diferenciales de las masas intraselares. La marcada brosis e hipervascularización complejizan la cirugía y predispone a complicaciones.

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Intrasellar schwannoma: A rare case of pituitary incidentaloma

Cited by 4 publications

References 8 publications

Ectopic schwannoma of the sellar region in a 1-year-old child: A case report and review of literature

Ectopic schwannoma of the sellar region in a 1-year-old child: A case report and review of literature

Hard calcified intrasellar schwannoma mimicking pituitary adenoma: A case report and review of the literature

Schwannoma como diagnóstico diferencial de masas selares: reporte de un caso y revisión de la literatura

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