Hard calcified intrasellar schwannoma mimicking pituitary adenoma: A case report and review of the literature

Sharifi, Guive; Bakhtevari, Mehrdad Hosseinzadeh; Alghasi, Mohsen; Saberi, Masood; Dehghan, Mahmood; Bidari, Farahnaz; Rezaei, Omidvar

doi:10.1016/j.clineuro.2015.06.001

Cited by 11 publications

(10 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…As with pituitary adenomas, intrasellar schwannomas often present as a mass lesion with an iso-to-hypointense signal on T1WI with homogeneous contrast enhancement; whereas on T2WI, they commonly show a more hyperintense signal than pituitary adenomas. In a study conducted by Sharifi et al, 1 the MRI findings of a intrasellar schwannoma showed the lesion was hard calcified. In our case, the MRI signals were quite mixed, indicating the internal components were complex and various.…”

Section: Discussionmentioning

confidence: 98%

“…Recently, Sharifi et al performed a literature review of intrasellar schwannomas reported before, all of which presented a suprasellar or parasellar extension similar to that of the present case. 1 …”

Section: Discussionmentioning

confidence: 99%

“…In fact, only 24 cases of intrasellar schwannoma have been reported in the literature up to now. 1 Partly because of the diversity and visual similarity of intrasellar or perasellar lesions, neurosurgeons and endocrinologists are often hard-pressed to make accurate preoperative diagnoses. Here, we present an unusual case of schwannoma in the sellar region in a patient who presented with symptoms of headache, hypothyroidism, and visual disturbance.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Schwannoma in Sellar Region Mimics Invasive Pituitary Macroadenoma

Kong

Ma³

et al. 2016

Medicine

View full text Add to dashboard Cite

In central nervous system, schwannomas, as ubiquitous tumors, mostly originate from sensory nerves like auditory and trigeminal nerves. However, intrasellar schwannomas are extremely rare. They are often misdiagnosed as pituitary adenomas.We report a rare case of schwannoma in the sellar region—a challenging diagnosis guided by clinical presentations, radiological signs, and postoperative pathological test.We represent a 65-year-old woman who had suffered from headaches, hypothyroidism, and visual disturbance. Her MRI revealed an abnormal sellar region mixed-signal mass lesion with suprasellar, left parasellar, and sellar floor invasiveness. We present detailed analysis of the patient's disease course and review relevant literatures. Written informed consent was obtained from the patient for publication of this article. A copy of the written consent is available for review by the editors of MEDICINE. Because this article does not involve any human or animal trials, there is no need to conduct special ethic review and the ethical approval is not necessary.When surgically treated, her specimen revealed a typical histopathology pattern of schwannoma. The patient's symptoms improved a lot after surgery and he continues to be under observation.Despite its rarity, intrasellar schwannoma should be considered in the differential diagnosis of sellar lesions that mimic pituitary adenomas.

show abstract

Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Schwannoma in Sellar Region Mimics Invasive Pituitary Macroadenoma

Kong

Ma³

et al. 2016

Medicine

View full text Add to dashboard Cite

show abstract

“…A total of 21 English-language articles documenting calcified lesions of the sellar region, published from 1961 to 2015, were retrieved from the database. 4,[6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25] Pathologies included cerebral aneurysm, 16 chondroid chordoma, 20 chondroma, 13 craniopharyngiomas, 19,22 OCs, [6][7][8][9][10][11] odontome, 18 osteoma, 17 pituitary adenomas, 15,21 pituitary stone, 25 Rathke cleft cyst, 23 retinoblastoma, 14 schwannoma, 24 and xanthogranuloma. 12 Among them, six patients were documented as OC cases.…”

Section: Demographic Datamentioning

confidence: 99%

“…Besides OCs, diverse pathologies have been reported as calcified lesions in the sellar region. [12][13][14][15][16][17][18][19][20][21][22][23][24][25] These are, except for craniopharyngiomas, reports of extremely rare instances, and each case is ranked at a lower probability than OCs among the differential diagnoses. OCs comprised 29% (6/21) of all the reported calcified masses of the sellar region.…”

Section: Studymentioning

confidence: 99%

Osteochondroma Presenting as a Calcified Mass in the Sellar Region and Review of the Literature

Sekiguchi

Tsutsumi

Arai

et al. 2016

J Neurol Surg A Cent Eur Neurosurg

View full text Add to dashboard Cite

Osteochondroma (OC) is the most common benign bone neoplasm. It infrequently occurs in the cranial cavity as a calcified lesion and very rarely presents in the sellar region. The present study summarizes the knowledge about OCs of the sellar region. We searched the literature search for the clinical appearance of OCs and other calcified pathologies occurring in the sellar region. A total of 21 English-language articles published from 1961 to 2015 documented cases of calcified lesions in the sellar region including cerebral aneurysm, chondroid chordoma, chondroma, craniopharyngioma, OC, odontome, osteoma, pituitary adenoma, pituitary stone, Rathke cleft cyst, retinoblastoma, schwannoma, and xanthogranuloma. Among them, six were OC cases: three in the parasellar region and three in the sellar-suprasellar region. Patients with sellar-suprasellar OCs presented with visual loss and hypopituitarism; patients with parasellar OCs did not show these symptoms. OCs appeared as irregular and multilobulated calcifications on X-ray and computed tomography. On magnetic resonance imaging, OCs showed variable intensity on T1-weighted sequences and consistently heterogenous intensity on T2. Four patients underwent transcranial tumor resection, and the transsphenoidal route was selected for one. Five of the six resulted in a partial resection or internal decompression with a satisfactory outcome. Calcified tumors occurring in the sellar region may be OCs, especially if they appear as irregular multilobulated calcification.

show abstract

Intra-Suprasellar Schwannoma Presumably Originating from the Internal Carotid Artery Wall

et al. 2017

View full text Add to dashboard Cite

Intracranial schwannomas are common but intra-suprasellar schwannomas are extremely rare. We represent the case of a 57-year-old woman with an intra-suprasellar tumor that was presurgically diagnosed as an anterior clinoidal meningioma. Intraoperatively it adhered tightly to the internal carotid artery wall and could not easily be dissected, possibly leading to profuse hemorrhage and sacrifice of the carotid artery with coil embolization. Histopathology demonstrated a schwannoma. We reviewed and summarized the clinical, imaging, and intraoperative findings of previously reported intra-suprasellar schwannomas.

show abstract

Hard calcified intrasellar schwannoma mimicking pituitary adenoma: A case report and review of the literature

Cited by 11 publications

References 22 publications

Schwannoma in Sellar Region Mimics Invasive Pituitary Macroadenoma

Schwannoma in Sellar Region Mimics Invasive Pituitary Macroadenoma

Osteochondroma Presenting as a Calcified Mass in the Sellar Region and Review of the Literature

Intra-Suprasellar Schwannoma Presumably Originating from the Internal Carotid Artery Wall

Contact Info

Product

Resources

About