Intraoral Fixed Drug Eruption Following Tetracycline Administration

Murray, Virginia Klute; DeFeo, Charles P.

doi:10.1902/jop.1982.53.4.267

Cited by 11 publications

(6 citation statements)

References 5 publications

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“…Commonly incriminated drugs for bullous FDE are rifampicin, 53 metronidazole, 58 paracetamol, 57 paclitaxel, 56 vinburnine, 55 erythromycin, 54 and ibuprofen 52 . The involvement of the oral mucous membrane 59,60 /lips, glans penis/genitals, 45,61–63 perineal area, 64,65 and tongue 66 is fairly common. Abrupt appearance of bullous lesions and/or erosions is the presenting morphology, 65 and may or may not be accompanied by lesions elsewhere on the skin 60 .…”

Section: Clinical Featuresmentioning

confidence: 99%

Fixed drug eruption (FDE): changing scenario of incriminating drugs

Sehgal¹,

Srivastava²

2006

Int J Dermatology

106

115

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Section: Clinical Featuresmentioning

confidence: 99%

Fixed drug eruption (FDE): changing scenario of incriminating drugs

Sehgal¹,

Srivastava²

2006

Int J Dermatology

106

115

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“…To the best of our knowledge, we could find only seven cases of intraoral involvement of FDE in the English literature [Table 1]. [151617181920]…”

Section: Discussionmentioning

confidence: 99%

Fixed drug eruptions with intraoral presentation

Srivastava

Bihari²,

Jyoti

et al. 2015

Indian J Dent

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“…The encrusted appearance of the lips and the intraoral erythematous appearance are indicative of active phase of FDE [6] whereas the violet macular rash over the trunk and forearm imply recovery phase, which is characterized by hyper pigmented areas. [7] The assessment of ADR is done by means of Naranjo's ADR scale. A score of >9 is indicative of defi nite ADR.…”

Section: Discussionmentioning

confidence: 99%

Paracetamol induced fi xed drug eruptions: A case report

Santosh¹,

Nagaraj²,

Bose³

2014

IJMDCR

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To report a case of fi xed drug eruption (FDE) due to paracetamol intake. FDE is cutaneous reactions in already sensitized individuals. The characteristic of FDE is recurrence at same site on repeated insults with the off ending drug. Paracetamol induced FDE is widely reported in children and adolescents but not among elderly individuals. A 62-year-old male patient had a chief complaint of burning sensation in lips and oral cavity since 3 days. History revealed intake of paracetamol. Encrusted lesions were present on the cutaneous surfaces of lips, and erythematous areas were present on the anterior third of the hard palate. Based on Naranjo's casualty assessment scale, provisional diagnosis of adverse drug reaction (ADR) was given. All drugs were stopped, but the patient had a similar episode of such lesions on the same site after 8 weeks. This establishes the diagnosis of FDE due to paracetamol ingestion. Though paracetamol is widely used and is considered a safe drug, ADR to it are possible and reported earlier. Clinical signifi cance: Reporting of FDE to dentist is uncommon. But on encountering such a situation, the dentist should be able to identify FDE and isolate the causative drug by means of history. A simple clinical assessment scale like Naranjo's casualty assessment scale can establish the presence of ADR.

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Intraoral Fixed Drug Eruption Following Tetracycline Administration

Cited by 11 publications

References 5 publications

Fixed drug eruption (FDE): changing scenario of incriminating drugs

Fixed drug eruption (FDE): changing scenario of incriminating drugs

Fixed drug eruptions with intraoral presentation

Paracetamol induced fi xed drug eruptions: A case report

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