Fixed drug eruption (FDE): changing scenario of incriminating drugs

Sehgal, Virendra; Srivastava, Govind

doi:10.1111/j.1365-4632.2006.02853.x

Cited by 106 publications

(132 citation statements)

References 194 publications

(305 reference statements)

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“…Ingestion of the causative agent may occur via any route, including oral, rectal, or intravenous. 23 In this clinical situation, there was a temporal association between the administration of Ofloxacin and Ornidazole and the onset of eruptions. The manifestations reduced on discontinuing the offending agents.…”

Section: Discussionmentioning

confidence: 99%

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Ofloxacin/ornidazole induced fixed drug eruptions: a case report

Manchukonda¹,

Ramakrishna²

2016

Int J Basic Clin Pharmacol

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Section: Discussionmentioning

confidence: 99%

“…22,23 Further questioning may reveal prior episodes of fixed drug eruption, atopic disease, or other past drug reactions. Family history may render a history of atopy, drug reactions, or diabetes mellitus.…”

Section: Discussionmentioning

confidence: 99%

Ofloxacin/ornidazole induced fixed drug eruptions: a case report

Manchukonda¹,

Ramakrishna²

2016

Int J Basic Clin Pharmacol

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“…Lesion can appear on any part of the skin or mucous membranes within a day to a few weeks after administering the causative drug. It resolves with residual hyperpigmentation (8,9). Generalized bullous drug eruption is severe form of FDE with mortality rate of 22% (10).…”

Section: Discussionmentioning

confidence: 99%

Pulmonary tuberculosis with fixed drug eruption to all first-line anti-tuberculosis drugs

Amanda¹,

Nurwidya²,

Isbaniyah³

2017

Respir Case Rep

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Tuberculosis (TB) is still one of the leading causes of mortality worldwide. Treatment with anti-TB drugs sometimes results in side effects for patients, including drug reactions, both allergic and non-allergic. Cutaneous adverse drug reaction is the most common side effect of anti-TB drugs, but severe reaction is rare. Here, we report rare case of a 34-year-old male who presented with pulmonary TB and fixed drug eruption to all first-line anti-TB therapies. After ingesting anti-TB regimen, multiple skin erosions and blisters occurred. Skin biopsy was performed and result was epidermis with subepidermal bullous. The patient's condition deteriorated, he developed severe hypoxemia, and unfortunately, he died during fixed drug eruption treatment.

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“…İlaç, travma veya visserokutanöz refleksle ilişkili olup olmadığı ile ilgili çalışmalar yapılmaktadır. 1,2 Tedavide öncelikli olan sorumlu ilacın kesilmesidir. Bunun dışında hafif olgular topikal kortikosteroid, şiddetli olgular sistemik kortikosteroid ve erode lezyonlar ıslak pansuman tedavisi ile kısa sürede genellikle postinflamatuar hiperpigmentasyon bırakarak iyileşir.…”

Section: 8unclassified