Ofloxacin/ornidazole induced fixed drug eruptions: a case report

Manchukonda, Ravi Shankar; Ramakrishna, Manjushree

doi:10.18203/2319-2003.ijbcp20160776

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2019

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“…[17][18][19] FDE due to other antibiotic FDCs like fluoroquinolone with nitroimidazole combinations have been reported. 20,21 The present case was presented to document an uncommon side effect of a commonly prescribed FDC, particularly in India. Cross reactions can also occur with structurally similar compound like tinidazole and cephalosporin combination.…”

Section: Discussionmentioning

confidence: 99%

Cefixime and ornidazole combination induced fixed drug eruption: a case report

Murugesan

Raj

Adhimoolam

2019

Int J Basic Clin Pharmacol

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Cefixime, a third generation cephalosporin and ornidazole, a nitroimidazole is used for a wide variety of conditions like urinary tract infections, otitis media, pharyngitis, uncomplicated gonorrhea and anaerobic infections. Fixed drug eruption (FDE) is commonly associated with anticonvulsants, antimicrobials and NSAIDs. Here we report a case of a rare cefixime and ornidazole combination induced fixed drug eruption. A 39 year old male developed hyper-pigmented patches over both forearms and left thigh after consuming fixed dose combination of cefixime and ornidazole tablet for the treatment of urinary tract infection.

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Section: Discussionmentioning

confidence: 99%