Intraocular Inflammation Associated with Ocular Toxoplasmosis: Relationships at Initial Examination

Clinical pattern of ocular toxoplasmosis treated in a referral centre in Serbia

“…22,26 However, the rate of vitritis was lower than generally reported, 22,26,29,30 which may suggest that the level of vitreous haze was not always reliably recorded, particularly if low.…”

“…The 1.7% of cataract was similar to the findings of Balasundaram et al 30 and Tugal-Tutkun et al, 26 but considerably lower than the 13% reported by Bosch-Driessen et al; 5 the comparatively high rate of complications in the latter series is presumably due to the longer follow-up. Interestingly, although raised IOP is often associated with an OT episode 23,29,30 glaucoma as a complication is rare; that is, in the study of TugalTutkun et al, although an IOP rise was seen in 8% patients during active OT, there was no case of glaucoma as a complication, 26 nor was it seen in the series of Balasundaram et al 30 In our series, one case was complicated by glaucoma secondary to OT.…”

Ocular toxoplasmosis: the influence of patient age

“…Mets et al (1996) showed that 52 (58%) of 89 newborns with congenital T. gondii infection and ocular disease had macular lesions, which is substantially higher than the number expected if lesions were distributed randomly, considering the fact that the anatomic macula comprises only approximately 5% of the total retinal area. Other investigators have also shown a disproportionately high frequency of macular lesions among patients with ocular toxoplasmosis (Hogan et al 1964, Friedman & Knox 1969, Dodds et al 2008). Congenital T. gondii infection at an early stage of retinal development could favor macular involvement (before vascularization of the peripheral retina is complete).…”

Visual Outcome in Ocular Toxoplasmosis: A Case Series of 30 Patients from Ghana

“…They also found a relationship between the size of retinal lesion and age of patient, with older patients having larger lesions [15]. Dodds et al [21] have also reported that signs of increased inflammation leading to marked reduction of visual acuity in patients with toxoplasmic retinochoroiditis were related to older patient age and larger retinal lesions. These observations may be explained by the fact of a possible multiple recurrences of ocular toxoplasmosis that makes the scars larger in elder patients and also by reason of declining immunity with advancing age [20].…”