Patients in Serbia demonstrated ocular sarcoidosis as the first most common site of extrapulmonary sarcoid manifestations, with more often neuro-ophthalmologic lesions than in other European populations.

Purpose To analyze the clinical pattern of ocular toxoplasmosis (OT) in a referral centre in Serbia.Patients and methods The medical records of consecutive patients admitted for OT to the single referral centre for uveitis in Serbia between 2006 and 2010 were retrospectively analyzed. OT was diagnosed on the basis of typical fundus lesions and positive serology for Toxoplasma.

Background/Aim. Rhegmatogenous retinal detachment is a potentially blinding condition of the posterior segment of the eye. Currently, the only treatment modality is surgery and surgical options include scleral buckling, pars plana vitrectomy and pneumoretinopexy. Many factors may influence the outcome of the surgery. Well defined indications are essential for achieving the best postoperative results. The aim of this study was to assess anatomical and functional outcome of treatment with scleral buckling for macula-off rhegmatogenous retinal detachments. Methods. This prospective, nonrandomized, interventional study included consecutive patients underwent scleral buckling for macula-off retinal detachment in the tertiary centre for vitreoretinal surgery. Results. A total of 168 consecutive patients (mean age 58.2 ± 13.9 years) were included in the study. Postoperatively, anatomical success was achieved in 152 (90.5%) of the patients. Parameters that influenced the anatomical success included the number of retinal breaks

UVODUveitisi su grupa zapaljenjskih bolesti očiju, koje primarno zahvataju uvealni trakt (dužicu, cilijarno telo i sudovnjaču), mada se termin uveitis nekad koristi i u širem smislu, za zapaljenja koja pored uvealnog trakta zahvataju i retinu i optički nerv (1). Uveitisi se najčešće javljaju kod radno sposobne populacije, uzrasta od 20 do 50 godina. ređe se javljaju kod dece, ali su kod njih u čak 75% slučajeva praćeni komplikacijama (2, 3). komplikacije uveitisa mogu trajno oštetiti vid, te stoga uveitisi imaju veliki socio-ekonomsko-medicinski značaj (4). naime, uveitisi su uzrok slepila kod 10% slepih širom sveta i nalaze se na četvrtom mestu svih uzročnika slepila (4, 5).Prema poreklu uveitisi se dele na egzogene i endogene. egzogeni uveitisi nastaju posle povrede oka ili hirurške intervencije na oku kada patogeni agensi, najčešće bakterije ili gljivice prodru u njega (4). endogeni uveitisi mogu da budu udruženi sa drugim bolestima kao što su sarkoidoza, multipla skleroza, Behčetova bolest, Vogtkojanagi-Harada sindrom i juvenilni idiopatski artritis. Opisana je i udruženost endogenih uveitisa sa infekcijama, moguće usled sličnosti (molekulske mimikrije) između pojedinih komponenti mikroorganizama i struktura uvealnog trakta. Pored toga, endogeni uveitisi mogu biti i idiopatski. U osnovi endogenih uveitisa leže imunski mehanizmi, pri čemu imunski odgovor mogu da pokrenu kako strani, tako i sopstveni antigeni (npr. S-antigen) koji interleukin-4, interleukin-5, interleukin-12, interleukin-17, interleukin-23, interferon-gamma and other