Intramammary Propolis Formulation for Prevention and Treatment of Mastitis in Dairy Ruminants (RC.2.2.08–0003)

Bačić, Goran; Mačešić, Nino; Radin, Lada; Aladrović, Jasna; Matanović, Krešimir; Mašek, Tomislav; Brozić, Diana; Benić, Miroslav; Radic, Bozo; Bačić, Iva; Šuran, Jelena

doi:10.5958/2277-940x.2015.00165.5

Cited by 4 publications

(9 citation statements)

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“…In 17 cows, different staphylococci strains were identified. In descending order of prevalence, the strains were S. epidermidis (in 11 cows), S. aureus ( 3 ), S. schleiferi ( 2 ), and S. hominis ( 1 ). Other identified Gram-positive cocci belonged to the Micrococcus ( 3 ), Streptococcus ( 1 ), and Aerococcus ( 1 ) genera.…”

Section: Resultsmentioning

confidence: 99%

“…In descending order of prevalence, the strains were S. epidermidis (in 11 cows), S. aureus ( 3 ), S. schleiferi ( 2 ), and S. hominis ( 1 ). Other identified Gram-positive cocci belonged to the Micrococcus ( 3 ), Streptococcus ( 1 ), and Aerococcus ( 1 ) genera. Gram-positive bacilli were identified in only three samples, being two Bacillus spp.…”

Section: Resultsmentioning

confidence: 99%

“…( 30 ). Similarly, ethanolic extract of propolis can be used against Gram-negative bacteria such as K. pneumoniae , E. coli , or P. aeruginosa ( 1 , 8 , 26 ). An antimicrobial effect of Rosmarinus officinalis and Moringa oleifera was also recorded for Gram-negative microorganisms isolated from milk ( 4 , 20 ).…”

Section: Discussionmentioning

confidence: 99%

“…Although there are several studies focused on the antimicrobial effects of plant products ( 10 , 22 , 30 ) or bee products ( 1 , 8 , 26 ) on pathogens isolated from milk from mastitic cows, there are only few data regarding in vivo testing. In the context of increased multidrug resistance and demand for organic products, the high costs of treating mastitis and of the development of efficient new synthetic drugs, the low manufacturing cost of plant products, and the apparent lack of antimicrobial resistance to these phytochemicals, the aim of this study was to test in vivo two plant-based and propolis-containing products with previously proven in vitro efficacy ( 21 ).…”

Section: Introductionmentioning

confidence: 99%

“… Financial Disclosure Statement : The study received the financial support of the ( 1 ) Project Partnerships in Priority Areas Programme - PN II, developed with the support of MEN-UEFISCDI, project no. 148/2014; ( 2 ) Programme 2: Competitiveness of the Romanian economy through research, development and innovation: PN-III-P2-2.1-CI-2018-1472 no.…”

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confidence: 99%

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Efficacy of natural formulations in bovine mastitis pathology: alternative solution to antibiotic treatment

Pașca

Mărghitaș

Dezmirean

et al. 2020

Journal of Veterinary Research

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IntroductionBovine mastitis is an inflammatory disease of the udder that causes important economic losses in the animal breeding and dairy product industries. Nowadays, the conventional livestock antibiotic treatments are slowly being replaced by alternative treatments. In this context, the main aim of this study was to evaluate the efficacy of natural products in alternative treatment of bovine mastitis.Material and MethodsTwo natural formulations with previously suggested in vitro antimicrobial effect were tested in vivo on mastitic cows. Animals with a positive diagnosis for mastitis (n = 20) were divided into three treatment groups: two groups (n = 8) were administered formulations of propolis, alcoholic extracts of Brewers Gold and Perle hops, plum lichen, common mallow, marigold, absinthe wormwood, black poplar buds, lemon balm, and essential oils of oregano, lavender, and rosemary designated R4 and R7 (differing only in the latter being more concentrated) and one group (n = 4) a conventional antibiotic mixture. In vivo efficacy of treatments was evaluated by somatic cell and standard plate counts, the treatment being considered efficacious when both parameters were under the maximum limit.ResultsR7 was effective in the most cases, being therapeutically bactericidal in six out of eight cows, while R4 gave good results in three out of eight cows, and conventional antibiotics cured one out of four.ConclusionThese results suggest the possible therapeutic potential of these natural products in bovine mastitis.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

mentioning

confidence: 99%

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Efficacy of natural formulations in bovine mastitis pathology: alternative solution to antibiotic treatment

Pașca

Mărghitaș

Dezmirean

et al. 2020

Journal of Veterinary Research

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Intramammary honey preparation for treatment of subclinical bovine mastitis: a preliminary study

2019

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Pharmacoeconomic Analysis of the Different Therapeutic Approaches in Control of Bovine Mastitis: Phytotherapy and Antimicrobial Treatment

et al. 2022

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Mastitis in dairy cows is responsible for major economic losses on dairy farms worldwide as the most expensive and prevalent disease in dairy cattle. In spite of the fact that antibiotic therapy still remains the main treatment strategy for bovine mastitis, concerns about the shortcomings of this treatment approach are continuously raised. Hence, research on alternative treatments with increased effectiveness and reduced costs is needed. Therefore, we conducted a pharmacoeconomic analysis of conventional antibiotic vs. a proposed Phyto-Bomat treatment based on essential oils in bovine mastitis therapy. Treatments were compared from the farmer’s perspective in the domain of costs (expressed in total, direct and indirect, cost differences) and effectiveness (expressed in daily milk yield differences). Economic calculations were based on data from a dairy farm in Serbia. The average cost of conventional antibiotic treatment was estimated at EUR 80.32 consisting of therapy costs, veterinary services and milk rejection costs at EUR 16.54, EUR 17.68 and EUR 46.10, respectively. The average cost of Phyto-Bomat treatment was estimated at EUR 76.34 with therapy costs of EUR 34.34, veterinary costs of EUR 32.00 and rejection of milk costs of only EUR 10.00. Therefore, Phyto-Bomat results in cost savings approximating EUR 4 per each mastitis episode with the highest cost reductions obtained in milk rejection costs. This estimation of Phyto-Bomat’s economic benefits could be used as a starting point for the inclusion of this formulation as an alternative treatment approach with a focus on subclinical mastitis since it contributes to most of the financial losses.

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Intramammary Propolis Formulation for Prevention and Treatment of Mastitis in Dairy Ruminants (RC.2.2.08–0003)

Cited by 4 publications

References 0 publications

Efficacy of natural formulations in bovine mastitis pathology: alternative solution to antibiotic treatment

Efficacy of natural formulations in bovine mastitis pathology: alternative solution to antibiotic treatment

Intramammary honey preparation for treatment of subclinical bovine mastitis: a preliminary study

Pharmacoeconomic Analysis of the Different Therapeutic Approaches in Control of Bovine Mastitis: Phytotherapy and Antimicrobial Treatment

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