Intralesional Laser Treatment for Dermal Filler Complications

Schelke, Leonie; Decates, Tom; Lugt, Claudia I M van der; Pelzer, Levi; Mey, Gabrielle de; Velthuis, Peter

doi:10.1097/prs.0000000000004428

Cited by 12 publications

(19 citation statements)

References 14 publications

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“…A new technique for nodules/granuloma treatment was developed in recent years as an option before surgery: the intralesional laser treatment (ILT) to help remove the product; the area is treated by local introduction of a micro-optic laser fiber several times at different places in the target area. [119][120][121] Several hundred cases involving different types of fillers, especially permanent dermal fillers were treated by ILT. 119,120 This technique applied to the PCL filler showed benefit in the very few treated cases given the extremely low AE incidence.…”

Section: Treatment Guidelines For Pcl Filler Complicationsmentioning

confidence: 99%

<p>Polycaprolactone: How a Well-Known and Futuristic Polymer Has Become an Innovative Collagen-Stimulator in Esthetics</p>

Christen¹,

Vercesi²

2020

CCID

101

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Compared to other domains, tissue engineering and esthetics have dramatically expanded in recent years, leading to both major biomedical advances and futuristic perspectives. The two share a common approach based on biomaterials, especially polymers. This paper illustrates this with the example of polycaprolactone (PCL), a polymer synthesized in the early 1930s, and one of its most recent applications, a PCL-based collagen stimulator, a filler used in esthetics. PCL is biocompatible and biodegradable. Its specific physicochemical and mechanical properties, viscoelasticity and ease of shaping led to the production of PCL-based products with various shapes and durations dependent on its biodegradation kinetics. PCL has been safely used in the biomedical field for more than 70 years, from sutures to tissue and organ replacement by 3D printing. The PCL-based collagen stimulator is composed of PCL microspheres suspended in a carboxymethyl-cellulose gel carrier providing immediate and sustained volumizing effects when injected; the morphology, the biocompatibility of the PCL microspheres embedded with the collagen fibers produced all contribute to the creation of a unique 3D scaffold for a sustained effect. Its safety has been investigated in clinical studies and vigilance surveys. Recently published experts' recommendations on injection modalities and techniques should help further optimize treatment outcome and safety. This paper also integrates reviews and recommendations on the prevention and management of adverse events related to dermal and subdermal fillers including the PCL-based collagen stimulator. In addition, in terms of efficacy and safety, this product benefits from its daily clinical use in esthetics worldwide and continuous extensive fundamental and clinical research, both on it and the PCL polymer. Forthcoming data from further investigations will reinforce knowledge of the product and procedures in the field.

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Section: Treatment Guidelines For Pcl Filler Complicationsmentioning

confidence: 99%

<p>Polycaprolactone: How a Well-Known and Futuristic Polymer Has Become an Innovative Collagen-Stimulator in Esthetics</p>

Christen¹,

Vercesi²

2020

CCID

101

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“…Of 219 patients treated, a complete disappearance of nodules and lumps was observed in 62% and a partial improvement in 30% of patients (Cassuto et al, 2016). Schelke et al (2018) combined an 810 nm diode laser with a 1,470 nm diode laser in continuous-wave mode. They used fiber diameters between 200 μm and 600 μm for intralesional treatment of nodules and granulomas in 242 patients.…”

Section: Pmma-associated Adverse Events After Lip Augmentationmentioning

confidence: 99%

“…They used fiber diameters between 200 μm and 600 μm for intralesional treatment of nodules and granulomas in 242 patients. In 92% of cases they achieved an improvement (Schelke et al, 2018). We employed a subdermal, intralesional 1,064 nm neodymium-doped yttrium aluminum garnet (Nd:YAG) laser in combination with suction using a blunt liposuction cannula of 2.0-2.5 mm of diameter.…”

Section: Pmma-associated Adverse Events After Lip Augmentationmentioning

confidence: 99%

“…Schelke et al (2018) combined an 810 nm diode laser with a 1,470 nm diode laser in continuous-wave mode. They used fiber diameters between 200 μm and 600 μm for intralesional treatment of nodules and granulomas in 242 patients.…”

mentioning

confidence: 99%

“…Schelke et al (2018) combined an 810 nm diode laser with a 1,470 nm diode laser in continuous-wave mode. In 92% of cases they achieved an improvement(Schelke et al, 2018). In 92% of cases they achieved an improvement(Schelke et al, 2018).…”

mentioning

confidence: 99%

See 2 more Smart Citations

Polymethylmethacrylate-induced nodules of the lips: Clinical presentation and management by intralesional neodymium:YAG laser therapy

Goldman

Wollina

2018

Dermatologic Therapy

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The lips are essential part of the beauty and attractiveness of the human face. Lip augmentation has become an increasingly used method to improve appearance. Soft tissue fillers are the most commonly used tools. Permanent fillers, however, have been associated with unwanted side effects after lip augmentation. In the present article the present authors will focus on permanent fillers based on polymethylmethacrylate (PMMA). The present authors provide a short review on PMMA fillers and known associated adverse events. The present authors provide a critical review of treatment options. Illustrated by clinical cases The present authors report our preferred treatment of PMMA nodules on lips by intralesional neodymium:YAG laser and blunt suction cannula with or without minor surgery. K E Y W O R D Sintralesional laser therapy, lip augmentation, nodules, permanent fillers, polymethylmethacrylate

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