Intracranial Arterial Stenosis

Carvalho, Márcia; Oliveira, Ana; Azevedo, Elsa; Bastos-Leite, António J.

doi:10.1016/j.jstrokecerebrovasdis.2013.06.006

Cited by 45 publications

(40 citation statements)

References 97 publications

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“…This may suggest that the prevalence of ICAS has been increased and ICAS has become more important for public health in China over time. As in the previous studies by Carvalho et al [17] and by Nahab et al [18], we found that arterial hypertension was an independent indicator of ICAS. So we focus on these blood pressure indexes to find out which index is the most sensitive indicator of ICAS.…”

Section: Discussionsupporting

confidence: 89%

Different blood pressure indexes on intracranial arterial stenosis in Asymptomatic Polyvascular Abnormalities in Community study in China

Wang

Zhou

et al. 2015

Journal of Hypertension

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Section: Discussionsupporting

confidence: 89%

Different blood pressure indexes on intracranial arterial stenosis in Asymptomatic Polyvascular Abnormalities in Community study in China

Wang

Zhou

et al. 2015

Journal of Hypertension

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“…In cases with no defined aetiology of stroke, or if there was doubt whether imaging with non-invasive cerebral angiography showed an IAS or simply artefacts, a DSA was performed in order to confirm or infirm the presence of the stenosis. Indeed, DSA is considered as the confirmation standard for the diagnosis of IAS [28]. Although this technique is invasive, there were no following complications in our study.…”

Section: Discussionmentioning

confidence: 62%

High Frequency of Intracranial Arterial Stenosis and Cannabis Use in Ischaemic Stroke in the Young

et al. 2014

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Background: Leading aetiologies of ischaemic stroke in young adults are cervico-cerebral arterial dissections and cardio-embolism, but the causes remain undetermined in a considerable proportion of cases. In a few reports, intracranial arterial stenosis has been suggested to be a potential cause of ischaemic stroke in young adults. The aim of our work was to evaluate the frequency, characteristics and risk factors of intracranial arterial stenosis in a prospective series of young ischaemic stroke patients. Methods: The study was based on a prospective consecutive hospital-based series of 159 patients aged 18-45 years who were admitted to our unit for an acute ischaemic stroke from October 2005 to December 2010. A structured questionnaire was used in order to assess common vascular risk factors such as hypertension, diabetes, hypercholesterolemia, use of tobacco, alcohol and illicit drugs, migraine, and, in women, oral contraceptive use. A systematic screening was performed, including the following: brain magnetic resonance imaging or, if not feasible, brain computed tomography scan, carotid and vertebral Duplex scanning and trans-cranial Doppler sonography, 3D time-of-flight magnetic resonance cerebral angiography or cerebral computed tomography angiography. Long-duration electrocardiography, trans-thoracic and trans-oesophageal echocardiography were performed and laboratory blood investigations were extensive. Urine samples were screened for cannabinoids, cocaine, amphetamine and methylene-dioxy-methamphetamine. When this initial work-up was inconclusive, trans-femoral intra-arterial selective digital subtraction angiography with reconstructed 3D images was performed. Results: In this series, 49 patients (31%) had intracranial arterial stenosis. Other defined causes were found in 91 patients (57%), including cardio-embolism in 32 (20%), cervical dissection in 23 (14%), extracranial atherosclerosis in 7 (4%), haematological disorders in 7 (4%), small vessel disease in 1, and isolated patent foramen ovale in 21 (13%); in 19 patients (12%), ischaemic stroke was related to an undetermined aetiology. Comparing risk factors between patients with intracranial arterial stenosis and those with other definite causes showed that there were only two significant differences: a lower age and a higher frequency of vasoactive substances (especially cannabis) in patients with intracranial arterial stenosis. All intracranial arterial stenosis in patients who used vasoactive substances were located in several intracranial vessels. Conclusions: Intracranial arterial stenosis may be an important mechanism of stroke in young patients and it should be systematically investigated using vascular imaging. Strong questioning about illicit drug consumption (including cannabis) or vasoactive medication use should also be performed. It should be emphasized for health prevention in young adults that cannabis use might be associated with critical consequences such as stroke.

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“…This can occur from atherosclerosis, infection, radiation exposure, or inflammatory conditions that cause vasculitis, or it can be idiopathic in cases such as Moyamoya disease. 2,3,11 The most common of these causes is atherosclerosis. The development of ICAD shares many of the same risk factors as coronary atherosclerosis.…”

Section: Pathophysiology and Diagnosis Of Intracranial Atherosclerotimentioning

confidence: 99%

Internal Carotid Artery Stenting for Intracranial Atherosclerosis

Osbun¹,

Kim

2014

Methodist DeBakey Cardiovascular Journal

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Intracranial Arterial Stenosis

Cited by 45 publications

References 97 publications

Different blood pressure indexes on intracranial arterial stenosis in Asymptomatic Polyvascular Abnormalities in Community study in China

Different blood pressure indexes on intracranial arterial stenosis in Asymptomatic Polyvascular Abnormalities in Community study in China

High Frequency of Intracranial Arterial Stenosis and Cannabis Use in Ischaemic Stroke in the Young

Internal Carotid Artery Stenting for Intracranial Atherosclerosis

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