Internal Carotid Artery Stenting for Intracranial Atherosclerosis

Intracranial atherosclerotic disease

“…Endovascular intervention is a minimally invasive method to recanalize an occluded vessel, and it can reduce the incidence of watershed infarcts secondary to chronic cerebral ischemia caused by hypoperfusion (Osbun and Kim, 2014). Several published trials have now proven the benefit of endovascular treatment of acute ischemic stroke (Berkhemer et al, 2015; Campbell et al, 2015; Goyal et al, 2015; Jovin et al, 2015; Saver et al, 2015).…”

“…Third, morphological features may influence the outcomes of endovascular procedure, and lesions with negative remodeling may be prone to vessel injury, resulting in vessel dissection or hemorrhage (Zhu et al, 2016). The criteria eligible for angioplasty and stenting may include severe symptomatic intracranial stenosis (> 70%), at least two strokes caused by intracranial stenosis despite maximal medical management, and an interval from the most recent stroke of > 7 days (Osbun and Kim, 2014). The China Angioplasty and Stenting for Symptomatic Intracranial Severe Stenosis (CASSISS) trial, an ongoing, prospective, multicenter and randomized trial with experienced operators and qualified patient selection, aims to determine whether intracranial stenting demonstrates a benefit over medical management for patients with severe symptomatic ICAS (Gao et al, 2015).…”