Interventions for replacing missing teeth: maintaining and recovering soft tissue health around dental implants

Grusovin, Maria Gabriella; Coulthard, Paul; Worthington, Helen V; George, P Renjith; Esposito, Marco

doi:10.1002/14651858.cd003069.pub4

Cited by 26 publications

(11 citation statements)

References 42 publications

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“…6,7 However, because of their inability to efficiently antagonize the infection, 8 the therapeutic efficacy of these approaches is limited. 9 In addition, local and systemic administration of antibiotics may result in hypersensitivity reactions in allergic patients, as well as the development of antibiotic-resistant strains of pathogenic…”

Section: Introductionmentioning

confidence: 99%

An Antimicrobial Dental Light Curable Bioadhesive Hydrogel for Treatment of Peri-Implant Diseases

Sani

Portillo-Lara

Aldawood

et al. 2019

Matter

102

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Dental implants are the current solution for replacement of missing teeth. However, the majority of patients with implants suffer from implant diseases caused by microbial infection and bone loss. There is an unmet need for the treatment of dental diseases. We developed a safe, cheap, and fast applicable glue with antimicrobial properties, designed for the treatment of periodontal diseases. This material can be delivered in liquid form around the implant and solidified by using a dental light to prevent infection and promote bone healing.

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Section: Introductionmentioning

confidence: 99%

An Antimicrobial Dental Light Curable Bioadhesive Hydrogel for Treatment of Peri-Implant Diseases

Sani

Portillo-Lara

Aldawood

et al. 2019

Matter

102

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“…There is currently no definitive means for controlling or eliminating the bacterial biofilm on implants. 19 – 21 Current state-of-the-art treatments for implants are similar to those for periodontal disease and include mechanical debridement and/or medicinal means intended to retard the biofilm. For implant surfaces, these include abrasive cup polishing, abrasive air blasting, titanium brushes with cleansing agents such as sodium hypochlorite or povidone-iodine, chlorohexidine rinses, antibiotics, and antimicrobials.…”

Section: Introductionmentioning

confidence: 99%

Repeatedly Applied Peptide Film Kills Bacteria on Dental Implants

Wisdom

Chen

Yuca

et al. 2019

JOM

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The rising use of titanium dental implants has increased the prevalence of peri-implant disease that shortens their useful life. A growing view of peri-implant disease suggests that plaque accumulation and microbiome dysbiogenesis trigger a host immune inflammatory response that destroys soft and hard tissues supporting the implant. The incidence of peri-implant disease is difficult to estimate, but with over 3 million implants placed in the USA alone, and the market growing by 500,000 implants/year, such extensive use demands additional interceptive approaches. We report a water-based, nonsur-gical approach to address peri-implant disease using a bifunctional peptide film, which can be applied during initial implant placement and later reapplied to existing implants to reduce bacterial growth. Bifunctional peptides are based upon a titanium binding peptide (TiBP) optimally linked by a spacer peptide to an antimicrobial peptide (AMP). We show herein that dental implant surfaces covered with a bifunctional peptide film kill bacteria. Further, using a simple protocol for cleaning implant surfaces fouled by bacteria, the surface can be effectively recoated with TiBP-AMP to regain an antimicrobial state. Fouling, cleansing, and rebinding was confirmed for up to four cycles with minimal loss of binding efficacy. After fouling, rebinding with a water-based peptide film extends control over the oral microbiome composition, providing a novel nonsurgical treatment for dental implants.

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“…Seven studies fulfilled all the inclusion criteria, respectively three RCTs [19 -21], one Consensus report [22], one cohort study [23], one systematic review [24] and one Chochrane review [25].…”

Section: Resultsmentioning

confidence: 99%

“…A consensus report in 2019 concerning homecare maintenance stated that manual and powered toothbrushes are both equally useful in peri-implant health maintenance and that interdental brushes and dental floss are effective differently from the use of antiseptic mouthwashes [22]. Louropoulou et al ended their systematic review concluding that there was still a lack of evidence for the best homecare maintenance practice [24].…”

Section: Resultsmentioning

confidence: 99%

Role of Dental Implant Homecare in Mucositis and Peri-implantitis Prevention: A Literature Overview

Checchi¹,

Racca²,

Bencivenni³

et al. 2019

TODENTJ

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Background: Correlation between high plaque index and inflammatory lesions around dental implants has been shown and this highlights the importance of patient plaque control. Until now, knowledge of peri-implant home care practices has been based on periodontal devices. Objective: The aim of this overview is to identify the presence of scientific evidence that peri-implant homecare plays a role in mucositis and peri-implantitis prevention. Methods: Different databases were used in order to detect publications reflecting the inclusion criteria. The search looked into peri-implant homecare studies published from 1991 to 2019 and the terms used for the identification of keywords were: Dental implants, Brush, Interproximal brushing, Interdental brushing, Power toothbrush, Cleaning, Interdental cleaning, Interspace cleaning, Flossing, Super floss, Mouth rinses, Chlorhexidine. The type of studies included in the selection for this structured review were Randomized Clinical Trials, Controlled Clinical Trials, Systematic Reviews, Reviews, Cohort Studies and Clinical cases. Results: Seven studies fulfilled all the inclusion criteria: 3 RCTs, one Consensus report, one cohort study, one systematic review and one review. Other 14 studies that partially met the inclusion criteria were analyzed and classified into 3 different levels of evidence: good evidence for RCTs, fair evidence for case control and cohort studies and poor evidence for expert opinion and case report. Conclusion: Not much research has been done regarding homecare implant maintenance. Scientific literature seems to show little evidence regarding these practices therefore most of the current knowledge comes from the periodontal literature. Manual and powered toothbrushes, dental floss and interdental brushes seem to be useful in maintaining peri-implant health. The use of antiseptic rinses or gels does not seem to have any beneficial effects. It can be concluded that to better understand which are the most effective home care practices to prevent mucositis and peri-implantitis in implant-rehabilitated patients, new specific high evidence studies are needed.

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Interventions for replacing missing teeth: maintaining and recovering soft tissue health around dental implants

Abstract: Interventions for replacing missing teeth: maintaining and recovering so tissue health around dental implants.

Cited by 26 publications

References 42 publications

An Antimicrobial Dental Light Curable Bioadhesive Hydrogel for Treatment of Peri-Implant Diseases

An Antimicrobial Dental Light Curable Bioadhesive Hydrogel for Treatment of Peri-Implant Diseases

Repeatedly Applied Peptide Film Kills Bacteria on Dental Implants

Role of Dental Implant Homecare in Mucositis and Peri-implantitis Prevention: A Literature Overview

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