“…Past notable attempts to shorten orthodontic treatment time included Corticotomy Assisted Orthodontics (CAO) (Gantes, Rathbun & Anholm, 1990;Chung, Oh & Ko, 2001;Wilcko, Wilcko, Bouquot & Ferguson, 2001;Long, Pyakurel, Wang, Liao, Zhou & Lai, 2013) which is based on the principle of Regional Acceleratory Phenomenon, a term first coined by Frost (1981). Physiologically, this theory proposes that when the bone is decorticated, an exuberant bone remodelling phase occurs in which teeth can be rapidly moved through demineralized bone due to an enhancement in cell-mediated tooth movement.…”