Interrater reliability of schizoaffective disorder compared with schizophrenia, bipolar disorder, and unipolar depression – A systematic review and meta-analysis

Santelmann, Hanno; Franklin, Jeremy; Bußhoff, Jana; Baethge, Christopher

doi:10.1016/j.schres.2016.07.012

Cited by 29 publications

(17 citation statements)

References 48 publications

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“…In one out of three patients with SAD at first assessment, the diagnoses will change over time. This finding is in line with a systematic literature review and meta-analysis in which we found a Cohen's kappa reliability of 0.5 for SAD, compared to about 0.7 for its three main differential diagnoses (schizophrenia, bipolar disorder, and unipolar depression) (20). Clinically, this finding is important because treatment needs to be adjusted according to diagnostic change.…”

Section: Shift From Sadsupporting

confidence: 90%

“…The search algorithm has been described elsewhere in depth (20). In short, we searched Medline (via PubMed), Embase (via Ovid), and PsycINFO (via Ebsco host) databases from their inception until 28 May 2014, for rediagnosis studies of patients with SAD.…”

Section: Search Algorithmmentioning

confidence: 99%

“…In 2015, in a systematic review and meta-analysis, we demonstrated that the test-retest (t1-t2) reliability of SAD is considerably lower than that of its main differential diagnoses (20), indicating that diagnostic shift is frequent. We did not, however, analyze the direction(s) of diagnostic shift.…”

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confidence: 99%

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Diagnostic shift in patients diagnosed with schizoaffective disorder: a systematic review and meta‐analysis of rediagnosis studies

et al. 2016

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Diagnostic shift in SAD patients is substantial. Psychiatrists need to reassess the diagnosis during the course of the illness and to adjust treatment. Slightly more diagnoses of SAD are changed to schizophrenia than to affective disorders, and among patients rediagnosed with SAD, fewer have been diagnosed with schizophrenia than with affective disorders. Thus, at the diagnostic level, there seems to be a slight trend toward schizophrenia during the course of functional psychoses.

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Section: Shift From Sadsupporting

confidence: 90%

Section: Search Algorithmmentioning

confidence: 99%

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Diagnostic shift in patients diagnosed with schizoaffective disorder: a systematic review and meta‐analysis of rediagnosis studies

et al. 2016

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“…Diagnosis of schizoaffective disorder has been frequently used as a distinct psychiatric diagnosis in clinical practice [1]. But it is one of the most discussed topics since it has first defined by Kasasin in nosological terms because diagnostic criteria for schizoaffective disorder were derived from schizophrenia and bipolar disorder [2][3][4].…”

Section: Introductionmentioning

confidence: 99%

Oxidative parameters, oxidative DNA damage, and urotensin-II in schizoaffective disorder patients

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Aksoy

Elboğa

et al. 2018

Psychiatry and Clinical Psychopharmacology

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OBJECTIVE: Complexity of schizoaffective disorder makes the identification of its pathophysiology a great challenge and there are very limited published data about the role of oxidative stress. Oxidative DNA damage has not been investigated in schizoaffective disorder. Therefore, we aimed to evaluate oxidative DNA damage together with oxidative stress and urotensin-II in patients with schizoaffective disorder. METHODS: Fifty-four patients who were diagnosed as schizoaffective disorder bipolar type (27 of them were in symptomatic remission and 27 of them were not) and 27 healthy volunteers were included in the study. Total antioxidant status (TAS), total oxidant status (TOS), oxidative stress index (OSI), serum 8-hydroxy-2'-deoxyguanosine (8-OHdG), and urotensin-II (U-II) levels were calculated and evaluated. RESULTS: TAS and U-II levels were found to be lower in the patient group with and without remission when compared with the control group separately. There were no significant difference in terms of TOS, OSI, and 8-OHdG. Similar results were obtained when those in symptomatic remission and non-remission patient groups were combined and compared with the control group. CONCLUSION: TAS levels in schizoaffective disorder patients were lower than controls, which may mean a vulnerability to the oxidative stress but there were no differences in terms of oxidative DNA damage. U-II levels in schizoaffective disorder patients were significantly lower than controls in contrast with our previous study. ARTICLE HISTORY

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“…Santelmann et al (1) recently presented solid meta-analytical findings on the test-retest reliability of schizoaffective disorder (SZA). Since its introduction in 1933, the nosological definition of SZA has known contrasting conceptualizations (2)(3)(4).…”

Section: Diagnostic Reliability In Schizoaffective Disordermentioning

confidence: 99%

Diagnostic reliability in schizoaffective disorder

et al. 2016

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Interrater reliability of schizoaffective disorder compared with schizophrenia, bipolar disorder, and unipolar depression – A systematic review and meta-analysis

Cited by 29 publications

References 48 publications

Diagnostic shift in patients diagnosed with schizoaffective disorder: a systematic review and meta‐analysis of rediagnosis studies

Diagnostic shift in patients diagnosed with schizoaffective disorder: a systematic review and meta‐analysis of rediagnosis studies

Oxidative parameters, oxidative DNA damage, and urotensin-II in schizoaffective disorder patients

Diagnostic reliability in schizoaffective disorder

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