Interplay of coronary angiography and intravascular ultrasound in predicting long-term outcomes after heart transplantation

Suppressive effects of conversion from mycophenolate mofetil to everolimus for the development of cardiac allograft vasculopathy in maintenance of heart transplant recipients

“…Additionally, Potena et al showed that a greater increase in MIT (N0.35 mm) 1 to 5 years post-HTx was associated with poor clinical outcomes more than 5 years after post-HTx [19]. Based on our results that the MMF group exhibited a greater incidence of a larger increase in MIT (MIT ≥ 0.3 mm at the 1-year follow-up) than did the EVL group, EVL conversion from MMF may contribute to improvements in long-term outcome after HTx.…”

“…2.1, Terumo, Tokyo, Japan). Using cross-sectional IVUS images, we compared changes in the MIT, which is known to impact long-term outcome after HTx [17][18][19], and coronary vessel, plaque, and lumen volumes based on 3D-IVUS images in both the EVL and MMF groups.…”

Risk Stratification for Cardiac Allograft Vasculopathy in Heart Transplant Recipients – Annual Intravascular Ultrasound Evaluation –

“…The progression of intimal thickening≥0.5 mm in the first year after HTx is a reliable marker for adverse cardiac events, 9,11 and late MIT increase on IVUS was also recently reported as an additional sensitive marker for cardiovascular events and longterm prognosis. 25 Thus, continuous monitoring and the earliest possible intervention to reduce factors that will exacerbate CAV are important for improving late prognosis.…”

Current state of pediatric cardiac transplantation

“…Initial optimism has been tempered by technical issues, cost, and lack of meaningful end-points for management and/or prognosis. It is presently being used in a handful of centers on older children due to the size of the available catheters, and most often plays a secondary role (51). MRI is being trialed in a few centers but has yet to reach the level of replacing angiography, either from an imaging perspective or, more recently, microcirculation assessment (52).…”